Clostridioides difficile uses amino acids associated with gut microbial dysbiosis in a subset of patients with diarrhea.

Autor: Battaglioli EJ; Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Hale VL; Department of Surgery, Mayo Clinic, Rochester, MN, USA.; Department of Veterinary Preventive Medicine, Ohio State University, Columbus, OH, USA., Chen J; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Jeraldo P; Department of Surgery, Mayo Clinic, Rochester, MN, USA., Ruiz-Mojica C; Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Schmidt BA; Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Rekdal VM; Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Till LM; Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Huq L; Department of Surgery, Mayo Clinic, Rochester, MN, USA., Smits SA; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA., Moor WJ; Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Jones-Hall Y; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA., Smyrk T; Department of Laboratory Medicine and Pathology, Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA., Khanna S; Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Pardi DS; Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Grover M; Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Patel R; Department of Laboratory Medicine and Pathology, Division of Clinical Microbiology, Mayo Clinic, Rochester, MN, USA., Chia N; Department of Surgery, Mayo Clinic, Rochester, MN, USA., Nelson H; Department of Surgery, Mayo Clinic, Rochester, MN, USA., Sonnenburg JL; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA., Farrugia G; Division of Gastroenterology, Mayo Clinic, Jacksonville, FL, USA., Kashyap PC; Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA. kashyap.purna@mayo.edu.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2018 Oct 24; Vol. 10 (464).