Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Moonnoh R. Lee"'
Autor:
David J Hinton, Meghan E McGee-Lawrence, Moonnoh R Lee, Hoi K Kwong, Jennifer J Westendorf, Doo-Sup Choi
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88818 (2014)
Adenosine is known to regulate bone production and resorption in humans and mice. Type 1 equilibrative nucleoside transporter (ENT1) is responsible for the majority of adenosine transport across the plasma membrane and is ubiquitously expressed in bo
Externí odkaz:
https://doaj.org/article/2354df19d94f4c6ea264e4c3fc332f63
Autor:
Jeong-Hyun Kim, Victor M Karpyak, Joanna M Biernacka, Hyung Wook Nam, Moonnoh R Lee, Ulrich W Preuss, Peter Zill, Gihyun Yoon, Colin Colby, David A Mrazek, Doo-Sup Choi
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16331 (2011)
Adenosine is involved in several neurological and behavioral disorders including alcoholism. In cultured cell and animal studies, type 1 equilibrative nucleoside transporter (ENT1, slc29a1), which regulates adenosine levels, is known to regulate etha
Externí odkaz:
https://doaj.org/article/cf50ba33b545456389140e858a51d515
Publikováno v:
Brain and Behavior
Background Adenosine signaling has been implicated in several neurological and psychiatric disorders. Previously, we found that astrocytic excitatory amino acid transporter 2 (EAAT2) and aquaporin 4 (AQP4) are downregulated in the striatum of mice la
Autor:
Moonnoh R. Lee, Mark B. Consugar, Vicente E. Torres, Daniel G. Bichet, Eliecer Coto, Edgar Almeida, Jamie L. Sundsbak, Maurizio Clementi, Katharina Hopp, Vickie J. Kubly, Sandro Rossetti, Peter C. Harris, Nadja Bogdanova, Christina M. Heyer, Binu M. Paul
Publikováno v:
Kidney International. 85:383-392
Mutations to PKD1 and PKD2 are associated with autosomal dominant polycystic kidney disease (ADPKD). The absence of apparent PKD1/PKD2 linkage in five published European or North American families with ADPKD suggested a third locus, designated PKD3 .
Autor:
Doo Sup Choi, David J. Hinton, Moses Rodriguez, Istvan Pirko, Prasanna K. Mishra, Moonnoh R. Lee, Aleksandar Denic, Slobodan Macura
Publikováno v:
Bioanalysis. 4:1787-1804
The ongoing development of animal models of neurological and psychiatric disorders in combination with the development of advanced nuclear magnetic resonance (NMR) techniques and instrumentation has led to increased use of in vivo proton NMR spectros
Autor:
Doo Sup Choi, David A. Mrazek, David J. Hinton, Prasanna K. Mishra, Mark A. Frye, Slobodan Macura, Moonnoh R. Lee, Taylor L. Jacobson
Publikováno v:
Neuropharmacology. 62:2480-2488
Acamprosate is clinically used to treat alcohol-dependent patients. While the molecular and pharmacological mechanisms of acamprosate remain unclear, it has been shown to regulate γ-aminobutyric acid (GABA) or glutamate levels in the cortex and stri
Autor:
Nora Hammack, Doo Sup Choi, David J. Hinton, Yu Zhu, Hyung Wook Nam, Moonnoh R. Lee, Jerry C.P. Yin, Jinhua Wu, Sun Choi, Tae Hyun Kim
Publikováno v:
Biological Psychiatry. 69:1043-1051
Background Mice lacking type 1 equilibrative nucleoside transporter (ENT1 −/− ) exhibit increased ethanol-preferring behavior compared with wild-type littermates. This phenotype of ENT1 −/− mice appears to be correlated with increased glutama
Autor:
Sandy Johng, Suzanne E. Rohrback, Tae Hyun Kim, Doo Sup Choi, Nayoung Kang, Jinhua Wu, Moonnoh R. Lee
Publikováno v:
Biochemical and Biophysical Research Communications. 406:47-52
Adenosine-regulated glutamate signaling in astrocytes is implicated in many neurological and neuropsychiatric disorders. In this study, we examined whether adenosine A1 receptor regulates EAAT2 expression in astrocytes using pharmacological agents an
Autor:
Moonnoh R. Lee, Liana Asatryan, Doo Sup Choi, M. Saeed Dar, Daryl L. Davies, Hyung Wook Nam, Mahesh M. Thakkar
Publikováno v:
Alcoholism: Clinical and Experimental Research. 35:584-594
In the central nervous system, adenosine and adenosine 5'-triphosphate (ATP) play an important role in regulating neuronal activity as well as controlling other neurotransmitter systems, such as, GABA, glutamate, and dopamine. Ethanol increases extra
Publikováno v:
Alcoholism: Clinical and Experimental Research. 35:99-107
Background: Neurotensin receptors (NTS) regulate a variety of the biological functions of neurotensin (NT) in the central nervous system. Although NT and neurotensin receptors type 1 (NTS1) are implicated in some of the behavioral effects of ethanol,