Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Moona Sakari"'
Autor:
Katharina Ernst, Ann-Katrin Mittler, Veronika Winkelmann, Carolin Kling, Nina Eberhardt, Anna Anastasia, Michael Sonnabend, Robin Lochbaum, Jan Wirsching, Moona Sakari, Arto T. Pulliainen, Ciaran Skerry, Nicholas H. Carbonetti, Manfred Frick, Holger Barth
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Whooping cough is caused by Bordetella pertussis that releases pertussis toxin (PT) which comprises enzyme A-subunit PTS1 and binding/transport B-subunit. After receptor-mediated endocytosis, PT reaches the endoplasmic reticulum from where u
Externí odkaz:
https://doaj.org/article/ffe6325e744642199e112ed599bf0f26
Publikováno v:
ACS Infectious Diseases. 8:433-456
The paradigm of antivirulence therapy dictates that bacterial pathogens are specifically disarmed but not killed by neutralizing their virulence factors. Clearance of the invading pathogen by the immune system is promoted. As compared to antibiotics,
Autor:
Moona, Sakari, Mai T, Tran, Jamie, Rossjohn, Arto T, Pulliainen, Travis, Beddoe, Dene R, Littler
Publikováno v:
The Journal of biological chemistry. 298(5)
Bordetella pertussis is the causative agent of whooping cough, a highly contagious respiratory disease. Pertussis toxin (PT), a major virulence factor secreted by B. pertussis, is an AB5-type protein complex topologically related to cholera toxin. Th
Autor:
Moona Sakari, Mai T. Tran, Jamie Rossjohn, Arto T. Pulliainen, Travis Beddoe, Dene R. Littler
Bordetella pertussis is the causative agent of whooping cough, a highly contagious respiratory disease. Pertussis toxin (PT), a major virulence factor secreted by B. pertussis, is an AB5-type protein complex topologically related to cholera toxin. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d6714830f26eabf742f2f58ac408af