Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Moona Miettinen"'
Autor:
Moona Miettinen, Leena Mattsson, Natalia Tong-Ochoa, Mika Lastusaari, Kari Kopra, Arto T. Pulliainen, Ville Eskonen, Harri Härmä
Publikováno v:
Analytical Chemistry
Post-translational modifications (PTMs) are one of the most important regulatory mechanisms in cells, and they play key roles in cell signaling both in health and disease. PTM catalyzing enzymes have become significant drug targets, and therefore, tr
Autor:
Arto T. Pulliainen, Lari Lehtiö, Michael O. Hottiger, Yashwanth Ashok, Avlokita Tiwari, Moona Miettinen, Mark S. Johnson, Mahlet Z. Tamirat, Danilo Kimio Hirabae de Oliveira, Katja Näreoja
Publikováno v:
ACS infectious diseases. 6(4)
Targeted pathogen-selective approach to antibiotic development holds promise to minimize collateral damage to the beneficial microbiome. The AB5-topology pertussis toxin (PtxS1-S5, 1:1:1:2:1) is a major virulence factor ofBordetella pertussis, the ca
Publikováno v:
Microbes and infection. 21(10)
Protein ADP-ribosylation is a reversible post-translational modification, which alters protein activity, localization, interactome or stability, leading to perturbation of cell signaling. This review summarizes the emerging data indicating that host