Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Moon-Jong Noh"'
Autor:
Moon Jong Noh1, Copeland, R. Ogden1, Youngsuk Yi1, Kyoung-Baek Choi2, Meschter, Carol3, Sally Hwang1, Chae-Lyul Lim2, Vivian Yip1, Jong-Pil Hyun2, Hyeon-Youl Lee2, Kwan Hee Lee1,4 ortholee@tissuegene.com
Publikováno v:
Cytotherapy (Taylor & Francis Ltd). Jun2010, Vol. 12 Issue 3, p384-393. 10p. 3 Color Photographs, 1 Diagram, 2 Graphs.
Publikováno v:
Current Gene Therapy
There have been major changes since the incidents of leukemia development in X-SCID patients after the treatments using retroviral gene therapy. Due to the risk of oncogenesis caused by retroviral insertional activation of host genes, most of the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45138cbc493a28c56dd71f39f3abba8e
http://europepmc.org/articles/PMC3182074
http://europepmc.org/articles/PMC3182074
Autor:
Hyeon-Youl Lee, Carol Meschter, Sally Hwang, Kwan Hee Lee, R. Ogden Copeland, Youngsuk Yi, Vivian Yip, Jong-Pil Hyun, Moon Jong Noh, Chae-Lyul Lim, Choi Kyoungbaek
Publikováno v:
Cytotherapy. 12:384-393
Background aims The aim was to evaluate cartilage regeneration in animal models involving induced knee joint damage. Through cell-mediated gene therapy methods, a cell mixture comprising a 3:1 ratio of genetically unmodified human chondrocytes and tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e6f51b88e7eb2bd007b5bb5150c882
https://doi.org/10.3109/14653240903470639
https://doi.org/10.3109/14653240903470639
Autor:
Vivian Yip, Youngsuk Yi, Sally Hwang, Moon Jong Noh, Chae-Lyul Lim, Lillian Yun, Hyeon-Youl Lee, Kun Bok Lee, Jong-Pil Hyun, Kwan Hee Lee, Asli Ayverdi, Kyoung Baek Choi
Publikováno v:
Tissue Engineering Part A. 15:2853-2863
Bone morphogenetic protein 2 (BMP2) was selected as a transgene to regenerate osteoporotic bone defects after several BMPs were tested using a bone formation study in nude mice. Human chondrocytes were transduced with a BMP2-containing retroviral vec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab9d1cd0bd43c0fca410b426a97e04f
https://doi.org/10.1089/ten.tea.2008.0578
https://doi.org/10.1089/ten.tea.2008.0578
Autor:
Youngsuk Yi, Hyun Joo Yoon, Dhara Somaiya, Yeon-Ju Lee, Chae-Lyul Lim, Choi Kyoungbaek, Kwan Hee Lee, Suk Bum Kim, Hyeon-Youl Lee, Moon Jong Noh
Publikováno v:
BMC Musculoskeletal Disorders
Background A localized non-surgical delivery of allogeneic human chondrocytes (hChonJ) with irradiated genetically modified chondrocytes (hChonJb#7) expressing transforming growth factor-β1 (TGF-β1) showed efficacy in regenerating cartilage tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8269fdf6503ea2cc18836c69f6091ad3
https://doi.org/10.1186/s12891-015-0599-x
https://doi.org/10.1186/s12891-015-0599-x
Autor:
Kyoung Baek Choi, Dug Keun Lee, Moon-Jong Noh, Guang Fan Chi, Youngsuk Yi, Chae-Lyul Lim, Seong-Jin Kim, In-Suk Oh, Young-Deog Cha, Hyeon-Youl Lee, Kwan Hee Lee, Jong-Pil Hyun, J. Kelly Ganjei, Sun U. Song, Jeoung-Uk Han
Publikováno v:
Tissue Engineering. 11:1516-1526
The purpose of this study was to investigate the efficacy of cartilage regeneration when using a mixture of transforming growth factor-beta1 (TGF-beta1)-producing human chondrocytes (hChon-TGF-beta1) and primary human chondrocytes (hChon) ("mixed cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d622a4eaf9b9e4f0f6ace9a85f567f
https://doi.org/10.1089/ten.2005.11.1516
https://doi.org/10.1089/ten.2005.11.1516
Autor:
Kyoung Baek Choi, Dug Keun Lee, Jeannie Kim, Chae-Lyul Lim, Guang Fan Chi, Eun Byul Lee, Kwan Hee Lee, In Suk Oh, Sally Hwang, Youngsuk Yi, Sun U. Song, Moon Jong Noh, Vivian Yip, Hyeon-Youl Lee, Jong-Pil Hyun
Publikováno v:
Tissue Engineering. 11:310-318
One of the most important factors in the production of cartilage is transforming growth factor beta1 (TGF-beta1). To obtain sustained release of TGF-beta1, a cell-mediated gene therapy technique was introduced. We infected chondrocytes with a retrovi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965d0293d7df5658ff9a1767f22d94a2
https://doi.org/10.1089/ten.2005.11.310
https://doi.org/10.1089/ten.2005.11.310
Autor:
Youngsuk Yi, Lillian Yun, Sung Ho Hahm, Kwan Hee Lee, Sally Hwang, Moon Jong Noh, Dug Keun Lee
Publikováno v:
Journal of Virological Methods. 121:127-136
Retroviral vectors have been widely used in gene therapy due to their simple genomic structure and high transduction efficiency. We report a construction of Moloney murine sarcoma virus (MoMSV) and Moloney murine leukemia virus (MoMLV) hybrid-based r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5708ad89a0bd1e7ac50bf1ee18a09dc2
https://doi.org/10.1016/j.jviromet.2004.05.014
https://doi.org/10.1016/j.jviromet.2004.05.014
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:483-486
A series of 5-fluorocytosine derivatives, 5'-deoxy-N-alkyloxycarbonyl-5-fluorocytosine-5'-carboxylic acid 6, were synthesized and evaluated for their antitumor activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97afe87f6c4818940322f7932acbabf
https://doi.org/10.1016/s0960-894x(01)00782-x
https://doi.org/10.1016/s0960-894x(01)00782-x
Publikováno v:
Journal of Bacteriology. 183:5937-5941
A lipase gene, lipK , and a lipase modulator gene, limK , of Pseudomonas sp. strain KFCC 10818 have been cloned, sequenced, and expressed in Escherichia coli . The limK gene is located immediately downstream of the lipK gene. Enzymatically active lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4720d1eb600332944f18001ae96dc48a
https://doi.org/10.1128/jb.183.20.5937-5941.2001
https://doi.org/10.1128/jb.183.20.5937-5941.2001