Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Moon-Jeong Ko"'
Autor:
Hee Jung Shin, Hye Soo Kim, Joon-Ik Ahn, Hye Joo Chung, Kyung Ji Jeong, Ho-Sang Jeong, Moon-Jeong Ko
Publikováno v:
Molecular & Cellular Toxicology. 6:169-177
Epigallocatechin gallate (EGCG), a major type of green tea polyphenol, has been reported to cause hepatotoxicity when used in excess. Micro-RNAs (miRNAs) are small non-coding RNA molecules that functions as negative regulators of gene expression. The
Publikováno v:
Genomics & Informatics. 8:41-49
Statins are competitive inhibitors of hydroxy-3-methyl glutaryl coenzyme A (HMG-CoA) reductase and used most frequently to reduce plasma cholesterol levels and to decrease cardiovascular events. However, statins al-so have been reported to have undes
Publikováno v:
Genomics & Informatics. 8:50-57
Mercuric chloride, a model nephrotoxicant was used to elucidate time- and dose- dependent global gene expression changes associated with proximal tubular toxicity. Rat kidney cell lines NRK-52E cells were exposed for 2, 6 and 12 hours and with 3 diff
Publikováno v:
Genomics & Informatics. 7:85-96
The differentiation of neural precursor cells (NPCs) into neurons and astrocytes is a process that is tightly controlled by complicated and ill-defined gene networks. To extend our knowledge to gene networks, we performed a temporal analysis of gene
Publikováno v:
Genomics & Informatics. 7:97-106
Epigallocatechin gallate (EGCG), a well-known antioxidant molecule, has been reported to cause hepatotoxicity when used in excess. However, the mechanism underlying EGCG-induced hepatotoxicity is still unclear. To better understand the mode of action
Publikováno v:
Genomics & Informatics. 6:117-125
Recently, obesity has become a worldwide public health concern and the use of anorectic drugs has drastically increased. In this study, sibutramine and phendimetrazine, representative marketed anorectics, were repeatedly administered per os on a dail
Publikováno v:
NeuroReport. 16:1647-1653
Collapsin response mediator protein-2 is highly expressed in the adult brain and it has been speculated to play roles in nervous system diseases. Studies determined for the first time whether collapsin response mediator protein-2 expression is altere
Publikováno v:
The Journal of biological chemistry. 281(18)
G(q/11) protein-coupled muscarinic receptors are known to regulate the release of soluble amyloid precursor protein (sAPPalpha) produced by alpha-secretase processing; however, their signaling mechanisms remain to be elucidated. It has been reported
Publikováno v:
Toxicology Letters. 180:S120
Autor:
Shinkyu Choi1, Un Hyoung Kim1,2, Eun-Jihn Roh1, Moon-Jeong Ko1, Ji-Eun Jung1, Hwa-Jung Kim1 hjkim@ewha.ac.kr
Publikováno v:
Journal of Biological Chemistry. 5/5/2006, Vol. 281 Issue 18, p12722-12728. 7p. 3 Diagrams, 2 Graphs.