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Akademický článek

Comparison of pharmaceutical properties and biological activities of prednisolone, deflazacort, and vamorolone in DMD disease models.

Autor: Liu G; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Lipari P; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Mollin A; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Jung S; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Teplova I; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Li W; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Ying L; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., More V; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Lennox W; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Yeh S; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., McGann E; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Moon YC; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Rice C; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Huarte E; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Gruszka B; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Ray B; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Goodwin E; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Buckendahl P; Rutgers University, Molecular Imaging Center, 41 Gordon Road, Piscataway, NJ 08854, United States., Yurkow E; Rutgers University, Molecular Imaging Center, 41 Gordon Road, Piscataway, NJ 08854, United States., Braughton B; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Narasimhan J; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Welch E; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Voronin G; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States., Weetall M; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, United States.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2024 Jan 20; Vol. 33 (3), pp. 211-223.

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Akademický článek

SAR studies toward discovery of emvododstat (PTC299), a potent dihydroorotate dehydrogenase (DHODH) inhibitor.

Autor: Baiazitov RY; PTC USA, NJ Center of Excellence Campus, 1013 Route 202/206, Bridgewater, NJ, 08807, USA. Electronic address: rbaiazitov@ptcbio.com., Qi H, Arasu T; Lachman Consultant Services, Inc., 1600 Stewart Ave, Suite 604, Westbury, NY, 11590, USA., Lennox W; PTC USA, Hopewell, 311 Pennington Rocky Hill Rd., Pennington, NJ, 08534, USA., Cao L; PTC USA, NJ Center of Excellence Campus, 1013 Route 202/206, Bridgewater, NJ, 08807, USA., Weetall M; PTC USA, NJ Center of Excellence Campus, 1013 Route 202/206, Bridgewater, NJ, 08807, USA., Furia B; PTC Therapeutics Inc, 100 Corporate Ct, South Plainfield, NJ, 07080, USA., Zhuo J; PTC Therapeutics Inc, 100 Corporate Ct, South Plainfield, NJ, 07080, USA., Choi S; Avelos Therapeutics, Inc., 21 Magokjungang 8-ro 7-gil, Gangseo-gu, Seoul, 07794, Republic of Korea., Kim MJ; PTC USA, NJ Center of Excellence Campus, 1013 Route 202/206, Bridgewater, NJ, 08807, USA., Sheedy J; PTC USA, NJ Center of Excellence Campus, 1013 Route 202/206, Bridgewater, NJ, 08807, USA., Davis T; Recludix Pharmaceuticals, 3545 John Hopkins Blvd, Suite 150, San Diego, CA, 92121, USA., Moon YC; PTC USA, NJ Center of Excellence Campus, 1013 Route 202/206, Bridgewater, NJ, 08807, USA.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2022 Dec 15; Vol. 244, pp. 114826. Date of Electronic Publication: 2022 Oct 05.

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Akademický článek

Guanidino quinazolines and pyrimidines promote readthrough of premature termination codons in cells with native nonsense mutations.

Autor: Morrill C; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA. Electronic address: cmorrill@ptcbio.com., Friesen WJ; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Babu S; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Baiazitov RY; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Du W; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Karloff DB; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Lee CS; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Moon YC; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Ren H; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Sierra J; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Tomizawa Y; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Vazirani P; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Welch EM; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Xue X; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA., Zhuo J; PTC Therapeutics, Inc., 100 Corporate Court, South Plainfield, NJ 07080, USA.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Nov 15; Vol. 76, pp. 128989. Date of Electronic Publication: 2022 Sep 20.

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