Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Moon L. Shin"'
Publikováno v:
Journal of Biological Chemistry. 281:19009-19018
Migration and proliferation of aortic endothelial cells (AEC) are critical processes involved in angiogenesis, atherosclerosis, and postangioplasty restenosis. Activation of complement and assembly of the C5b-9 complement complex have been implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2f9b44b573f15a0c131c4c3e78021d
https://doi.org/10.1074/jbc.m602055200
https://doi.org/10.1074/jbc.m602055200
Autor:
Susanna Weerth, Teodora Niculescu, Florin Niculescu, Moon L. Shin, Lucian Soane, Cedric S. Raine, Violeta Rus, Horea Rus
Publikováno v:
Annals of the New York Academy of Sciences. 1010:530-533
Complement activation is involved in the initiation of inflammation and antibody-mediated demyelination in experimental autoimmune encephalomyelitis (EAE). We investigated the role of MAC in apoptosis in myelin-induced EAE in complement C5-deficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfaa9d9d534b675a3c895115cf76020
https://doi.org/10.1196/annals.1299.098
https://doi.org/10.1196/annals.1299.098
Autor:
Teodora Niculescu, Moon L. Shin, Jae-Hyun Park, Lucian Soane, Tudor Badea, Horea Rus, Florin Niculescu
Publikováno v:
Journal of Neuroimmunology. 142:58-66
Sublytic C5b-9 alters the molecular phenotype of myotubes by inhibiting muscle-specific gene expression. Here, we showed that C5b-9 induced c-fos mRNA and transcription. Using c-fos promoter-CAT constructs and electrophoretic mobility shift assay (EM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7441d21488fc4316fb9b82bbc047eb87
https://doi.org/10.1016/s0165-5728(03)00261-3
https://doi.org/10.1016/s0165-5728(03)00261-3
Publikováno v:
The American Journal of Pathology. 163:1069-1080
Activation of the classical complement system is known to play a central role in autoimmune demyelination. We have analyzed the role of complement component C5 in experimental autoimmune encephalomyelitis (EAE) using C5-deficient (C5-d) and C5-suffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0755b084a4d1e26352c87e31cd7e82
https://doi.org/10.1016/s0002-9440(10)63466-9
https://doi.org/10.1016/s0002-9440(10)63466-9
Autor:
Florin Niculescu, Hila Sorana, Violeta Rus, Horea Rus, Lucian Soane, Matthew Fosbrink, Tudor C. Badea, Moon L. Shin
Publikováno v:
Journal of Biological Chemistry. 277:502-508
Proliferation of aortic smooth muscle cells contributes to atherogenesis and neointima formation. Sublytic activation of complement, particularly C5b-9, induces cell cycle progression in aortic smooth muscle cells. RGC-32 is a novel protein that may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0c5b85561772cd72a91415f95b3b02
https://doi.org/10.1074/jbc.m109354200
https://doi.org/10.1074/jbc.m109354200
Publikováno v:
The Journal of Immunology. 167:2305-2311
Apoptosis of oligodendrocytes is induced by serum growth factor deprivation. We showed that oligodendrocytes and progenitor cells respond to serum withdrawal by a rapid decline of Bcl-2 mRNA expression and caspase-3-dependent apoptotic death. Sublyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f32b18a1427044ccfdf1d0b0407ed7
https://doi.org/10.4049/jimmunol.167.4.2305
https://doi.org/10.4049/jimmunol.167.4.2305
Publikováno v:
Immunological Reviews. 180:49-55
Summary: Assembly of C5b-9 on cell membranes results in transmembrane channels and causes cell death. When the number of C5b-9 molecules is limited, nucleated cells are able to escape cell death by endocytosis and by shedding of membranes bearing C5b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf86465af8fc2c77000c558dcee8faf1
https://doi.org/10.1034/j.1600-065x.2001.1800104.x
https://doi.org/10.1034/j.1600-065x.2001.1800104.x
Requirements for Measles Virus Induction of RANTES Chemokine in Human Astrocytoma-Derived U373 Cells
Publikováno v:
Journal of Virology. 73:3117-3124
Interferons and chemokines play a critical role in regulating the host response to viral infection. Measles virus, a member of the Paramyxoviridae family, induces RANTES expression by astrocytes. We have examined the mechanism of this induction in U3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188da21efa93c45c51a503d20aa88acc
https://doi.org/10.1128/jvi.73.4.3117-3124.1999
https://doi.org/10.1128/jvi.73.4.3117-3124.1999
Publikováno v:
Journal of Biological Chemistry. 273:26977-26981
Sublytic complement activation on oligodendrocytes (OLG) down-regulates expression of myelin genes and induces cell cycle in culture. Differential display (DD) was used to search for new genes whose expression is altered in response to complement and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c506de325ba6def00e27c415cc866b
https://doi.org/10.1074/jbc.273.41.26977
https://doi.org/10.1074/jbc.273.41.26977