Zobrazeno 1 - 10
of 248
pro vyhledávání: '"Moon H Nahm"'
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209657 (2018)
Among 98 serotypes of Streptococcus pneumoniae, only a small subset regularly causes invasive pneumococcal diseases (IPD). We previously demonstrated that serotype 11A binds to ficolin-2 and has low invasiveness in children. Epidemiologic data sugges
Externí odkaz:
https://doaj.org/article/6cf17bf27a4b416fa803250582cbec9f
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93477 (2014)
Even though the pathogenicity and invasiveness of pneumococcus largely depend on capsular types, the impact of serotypes on post-viral pneumococcal pneumonia is unknown.This study was performed to evaluate the impact of capsular serotypes on the deve
Externí odkaz:
https://doaj.org/article/b63e70f8440d4a5caf1c79dd95951ac0
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97825 (2014)
Since nasopharyngeal carriage of pneumococcus precedes invasive pneumococcal disease, characteristics of carriage isolates could be incorrectly assumed to reflect those of invasive isolates. While most pneumococci express a capsular polysaccharide, n
Externí odkaz:
https://doaj.org/article/6e6252fa74b04cdc9bead3ad0544016c
Autor:
Romina Camilli, Brady L Spencer, Monica Moschioni, Vittoria Pinto, Francesco Berti, Moon H Nahm, Annalisa Pantosti
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100722 (2014)
BACKGROUND: Recent studies have identified Streptococcus pneumoniae serotype 11E and serovariant 11Av among isolates previously typed as 11A by classical serotyping methods. Serotype 11E and serovariant 11Av differ from serotype 11A by having totally
Externí odkaz:
https://doaj.org/article/2a830a5311a74898b98546bcd16e97bb
Autor:
Saeyoung Park, Moon H Nahm
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83810 (2013)
Streptococcus pneumoniae is a major human pathogen which expresses more than 90 serologically distinct capsular polysaccharides (PS) on the surface. Since pneumococcal PSs elicit protective antibodies against pneumococcal diseases, it is important to
Externí odkaz:
https://doaj.org/article/9f9360c94e6748bcb9e9231a44717653
Autor:
Kristen Feemster, William P. Hausdorff, Natalie Banniettis, Heather Platt, Priscilla Velentgas, Alejandra Esteves-Jaramillo, Robert L. Burton, Moon H. Nahm, Ulrike K. Buchwald
Publikováno v:
Vaccines, Vol 12, Iss 9, p 974 (2024)
Pneumococcal vaccines are a cornerstone for the prevention of pneumococcal diseases, reducing morbidity and mortality in children and adults worldwide. Pneumococcal vaccine composition is based on the polysaccharide capsule of Streptococcus pneumonia
Externí odkaz:
https://doaj.org/article/df5b5512f0a1450c8b212eea935fbaaf
Autor:
Shang-Chuen Wu, Hau-Ming Jan, Mary L. Vallecillo-Zúniga, Matthew F. Rathgeber, Caleb S. Stowell, Kaleb L. Murdock, Kashyap R. Patel, Hirotomo Nakahara, Carter J. Stowell, Moon H. Nahm, Connie M. Arthur, Richard D. Cummings, Sean R. Stowell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Microbial glycan microarrays (MGMs) populated with purified microbial glycans have been used to define the specificity of host immune factors toward microbes in a high throughput manner. However, a limitation of such arrays is that glycan pr
Externí odkaz:
https://doaj.org/article/c4280ad7b7c745f8a5a8f62ba788f3bd
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Reports conflict regarding which lectin-microbial ligand interactions elicit a protective response from the lectin pathway (LP) of complement. Using fluorescent microscopy, we demonstrate the human lectin ficolin-2 binds to Streptococcus pneumoniae s
Externí odkaz:
https://doaj.org/article/b82294322a3e495bbbdc1d3b3e49d6e3
Autor:
Hideki Sakatani, Masamitsu Kono, Gen Sugita, Denisa Nanushaj, Masayoshi Hijiya, Takuro Iyo, Tatsuya Shiga, Daichi Murakami, Norihito Kaku, Katsunori Yanagihara, Moon H. Nahm, Muneki Hotomi
Publikováno v:
Journal of Infection and Chemotherapy. 28:1452-1458
Since the introduction of pneumococcal conjugate vaccine, there have been warnings of an increase in infections caused by non-vaccine type of Streptococcus pneumoniae strains. Among them, nonencapsulated Streptococcus pneumoniae (NESp) has been repor
Autor:
Feroze A. Ganaie, Jamil S. Saad, Stephanie W. Lo, Lesley McGee, Stephen D. Bentley, Andries J. van Tonder, Paulina Hawkins, Jeremy D. Keenan, Juan J. Calix, Moon H. Nahm
Publikováno v:
Journal of Clinical Microbiology. 61
Streptococcus pneumoniae can produce a wide breadth of antigenically diverse capsule types, a fact that poses a looming threat to the success of vaccines that target pneumococcal polysaccharide (PS) capsule. Yet, many pneumococcal capsule types remai