3D Graph Contrastive Learning for Molecular Property Prediction

Autor: Moon, Kisung, Kwon, Sunyoung

Self-supervised learning (SSL) is a method that learns the data representation by utilizing supervision inherent in the data. This learning method is in the spotlight in the drug field, lacking annotated data due to time-consuming and expensive exper

Externí odkaz: http://arxiv.org/abs/2208.06360

METTL3 regulates alternative splicing of cell cycle-related genes via crosstalk between mRNA m(6)A modifications and splicing factors

Autor: Kim, Yeongjoo, Shin, Seungjae, Kwon, Sunyoung, Moon, Kisung, Baek, Su-Vin, Jo, Ahyoung, Kim, Hyung-Sik, Hwang, Gue-Ho, Bae, Sangsu, Kim, Yun Hak, Cho, Sung-Yup, Oh, Jung-Min

Publikováno v: Am J Cancer Res

N(6)-methyladenosine (m(6)A) modification in RNA affects various aspects of RNA metabolism and regulates gene expression. This modification is modulated by many regulatory proteins, such as m(6)A methyltransferases (writers), m(6)A demethylases (eras

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::39e4acc32c447b93e232d6444a54ee50
https://europepmc.org/articles/PMC10164804/

METTL3 regulates alternative splicing of cell cycle-related genes via crosstalk between mRNA m ⁶ A modifications and splicing factors.

Autor: Kim Y; Interdisplinary Program of Genomic Science, Pusan National University Yangsan, Korea.; Department of Biomedical Informatics, School of Medicine, Pusan National University Yangsan, Korea., Shin S; Department of Biomedical Sciences, Seoul National University College of Medicine Seoul, Korea., Kwon S; Department of Information Convergence Engineering, Pusan National University Yangsan, Korea.; School of Biomedical Convergence Engineering, Pusan National University Yangsan, Korea., Moon K; Department of Information Convergence Engineering, Pusan National University Yangsan, Korea., Baek SV; Department of Oral Biochemistry, Dental and Life Science Institute, School of Dentistry, Pusan National University Yangsan, Korea., Jo A; Department of Oral Biochemistry, Dental and Life Science Institute, School of Dentistry, Pusan National University Yangsan, Korea., Kim HS; Department of Oral Biochemistry, Dental and Life Science Institute, School of Dentistry, Pusan National University Yangsan, Korea.; Department of Life Science in Dentistry, School of Dentistry, Pusan National University Yangsan, Korea., Hwang GH; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine Seoul, Korea., Bae S; Department of Biomedical Sciences, Seoul National University College of Medicine Seoul, Korea.; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine Seoul, Korea., Kim YH; Department of Biomedical Informatics, School of Medicine, Pusan National University Yangsan, Korea.; Department of Anatomy, School of Medicine, Pusan National University Yangsan, Korea., Cho SY; Department of Biomedical Sciences, Seoul National University College of Medicine Seoul, Korea.; Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine Seoul, Korea.; Cancer Research Institute, Seoul National University Seoul, Korea., Oh JM; Department of Oral Biochemistry, Dental and Life Science Institute, School of Dentistry, Pusan National University Yangsan, Korea.; Department of Life Science in Dentistry, School of Dentistry, Pusan National University Yangsan, Korea.

Publikováno v: American journal of cancer research [Am J Cancer Res] 2023 Apr 15; Vol. 13 (4), pp. 1443-1456. Date of Electronic Publication: 2023 Apr 15 (Print Publication: 2023).