End-to-End Automation Enables High Throughput Spleen Volume Assessment for Computed Tomography Clinical Trials

Autor: Moon, Hyeonsoo

Delineation of CT abdominal anatomical structure, especially spleen segmentation is essential for measuring tissue volume and biomarkers, so that it can be utilized not only as liver diseases and infection diagnosis purposes, but also as computer-bas

Externí odkaz: http://etd.library.vanderbilt.edu/available/etd-04042018-144711/

SynSeg-Net: Synthetic Segmentation Without Target Modality Ground Truth

Autor: Huo, Yuankai, Xu, Zhoubing, Moon, Hyeonsoo, Bao, Shunxing, Assad, Albert, Moyo, Tamara K., Savona, Michael R., Abramson, Richard G., Landman, Bennett A.

Publikováno v: "Synseg-net: Synthetic segmentation without target modality ground truth." IEEE transactions on medical imaging 38, no. 4 (2018): 1016-1025

A key limitation of deep convolutional neural networks (DCNN) based image segmentation methods is the lack of generalizability. Manually traced training images are typically required when segmenting organs in a new imaging modality or from distinct d

Externí odkaz: http://arxiv.org/abs/1810.06498

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PI3K Inhibition Restores and Amplifies Response to Ruxolitinib in Patients with Myelofibrosis.

Autor: Moyo TK; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee.; Levine Cancer Institute, Charlotte, North Carolina., Kishtagari A; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Villaume MT; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee., McMahon B; University of Colorado, Denver, Colorado., Mohan SR; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Stopczynski T; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.; Center for Quantitative Sciences, Vanderbilt University, Nashville, Tennessee., Chen SC; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.; Center for Quantitative Sciences, Vanderbilt University, Nashville, Tennessee., Fan R; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.; Center for Quantitative Sciences, Vanderbilt University, Nashville, Tennessee., Huo Y; Department of Electrical and Computer Engineering, Vanderbilt University School of Medicine, Nashville, Tennessee., Moon H; Department of Electrical and Computer Engineering, Vanderbilt University School of Medicine, Nashville, Tennessee., Tang Y; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee., Bejan CA; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee., Childress M; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee., Anderson I; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Rawling K; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Simons RM; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Moncrief A; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Caza R; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Dugger L; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Collins A; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Dudley CV; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Ferrell PB; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee.; Program in Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee.; Center for Immunobiology, Vanderbilt University School of Medicine, Nashville, Tennessee., Byrne M; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Strickland SA; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee., Ayers GD; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.; Center for Quantitative Sciences, Vanderbilt University, Nashville, Tennessee., Landman BA; Department of Electrical and Computer Engineering, Vanderbilt University School of Medicine, Nashville, Tennessee.; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee., Mason EF; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee., Mesa RA; Wake Forest Baptist Cancer Center, Winston-Salem, North Carolina., Palmer JM; Department of Internal Medicine, Mayo Clinic, Scottsdale, Arizona., Michaelis LC; Medical College of Wisconsin, Madison, Wisconsin., Savona MR; Department of Internal Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee.; Program in Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee.; Center for Immunobiology, Vanderbilt University School of Medicine, Nashville, Tennessee.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Jul 05; Vol. 29 (13), pp. 2375-2384.