Signal Transduction by Epidermal Growth Factor Occurs through the Subclass of High Affinity Receptors

Autor: Defize, L. H. K., Boonstra, J., Meisenhelder, J., Kruijer, W., Tertoolen, L. G. J., Tilly, B. C., Hunter, T., Moolenaar, W. H., de Laat, S. W.

Publikováno v: The Journal of Cell Biology, 1989 Nov 01. 109(5), 2495-2507.

Externí odkaz: https://www.jstor.org/stable/1613746

The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein

Autor: Giepmans, B N, Moolenaar, W H

Publikováno v: Current Biology, 8(16), 931-4. CELL PRESS

Gap junctions mediate cell-cell communication in almost all tissues and are composed of channel-forming integral membrane proteins, termed connexins [1-3]. Connexin43 (Cx43) is the most widely expressed and the most well-studied member of this family

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::e1f637c4205f102a1d41de4e7326944a
https://research.rug.nl/en/publications/6c7ecad7-456c-4dd6-9fd4-ab70bd0d77c8

Protein tyrosine phosphorylation induced by lysophosphatidic acid in rat- 1 fibroblasts. Evidence that phosphorylation of map kinase is mediated by the G(i)-p21(ras) pathway

Autor: Hordijk, P. L., Verlaan, I., Van Corven, E. J., Moolenaar, W. H.

Publikováno v: Journal of Biological Chemistry, 269(1), 645-651. American Society for Biochemistry and Molecular Biology Inc.
Hordijk, P L, Verlaan, I, Van Corven, E J & Moolenaar, W H 1994, ' Protein tyrosine phosphorylation induced by lysophosphatidic acid in rat-1 fibroblasts. Evidence that phosphorylation of map kinase is mediated by the G(i)-p21(ras) pathway ', Journal of Biological Chemistry, vol. 269, no. 1, pp. 645-651 .

Lysophosphatidic acid (LPA) is a platelet-derived phospholipid that serves as a mitogen for fibroblasts. LPA activates its own G protein-coupled receptor(s) leading to stimulation of phospholipase C and inhibition of adenylate cyclase. Furthermore, L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::442a5c50562110dbe1304b670cc8ab38
https://research.vumc.nl/en/publications/7dab5623-b267-4640-9d5e-36465f4b1de8

G(i)-mediated activation of the p21(ras)-mitogen-activated protein kinase pathway by α2-adrenergic receptors expressed in fibroblasts

Autor: Alblas, J., Van Corven, E. J., Hordijk, P. L., Milligan, G., Moolenaar, W. H.

Publikováno v: Journal of Biological Chemistry, 268(30), 22235-22238. American Society for Biochemistry and Molecular Biology Inc.

The α2-adrenergic receptors are linked to inhibition of adenylylcyclase and, under certain circumstances, to stimulation of phospholipid hydrolysis via pertussis toxin-sensitive G proteins. Here we show that α2-adrenergic receptors can couple to an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::a5c08d618278610fa3fd3de69d5a01a7
https://research.vumc.nl/en/publications/8c88971d-64e0-4455-b561-0dbc110ea6db

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