Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mookwang Kwon"'
Autor:
Ju Hyun Lee, Mookwang Kwon, Woo Young Lim, Chae Rin Yoo, Youngik Yoon, Dasol Han, Jin-Hyun Ahn, Keejung Yoon
Publikováno v:
PLoS Pathogens, Vol 18, Iss 12, p e1011007 (2022)
YES-associated protein (YAP), a critical actor of the mammalian Hippo signaling pathway involved in diverse biological events, has gained increased recognition as a cellular factor regulated by viral infections, but very few studies have investigated
Externí odkaz:
https://doaj.org/article/0850100e478b45e78f8df08ae5469deb
Publikováno v:
EMBO reports. 24
Growing evidence suggests that the corticotropin-releasing hormone (CRH) signaling pathway, mainly known as a critical initiator of humoral stress responses, has a role in normal neuronal physiology. However, despite the evidence of CRH receptor (CRH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5405ccfe84b55cd9f0af5c97093eaac
https://doi.org/10.15252/embr.202255313
https://doi.org/10.15252/embr.202255313
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports
Although astrocytes have gained increased recognition as an important regulator in normal brain function and pathology, the mechanisms underlying their genesis are not well understood. In this study, we show that constitutive YAP activation by in ute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e47e8fbff1ff6805e82c8571b19a22e
http://link.springer.com/article/10.1038/s41598-020-63890-z
http://link.springer.com/article/10.1038/s41598-020-63890-z
Publikováno v:
Biochemical and Biophysical Research Communications. 513:392-397
The protein activator of protein kinase R (PKR) (PACT) is known to play important roles in PKR regulation and microRNA biogenesis. Based on the observation that PACT is specifically expressed in the ventricular zone (VZ) at the mid-neurogenic period,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd2eb408bf30294aa872544cf4ee38e
https://doi.org/10.1016/j.bbrc.2019.04.010
https://doi.org/10.1016/j.bbrc.2019.04.010
Autor:
Ju Hyun Lee, Dasol Han, Jae Youl Cho, Keejung Yoon, Mookwang Kwon, Sun Min Lee, Youngik Yoon, Hogyun Noh
Publikováno v:
Stem cells and development. 29(18)
The Hippo signaling pathway regulates cell proliferation and organ growth, and its activation is mainly reflected by the phosphorylation levels of Yes-associated protein (YAP). In this study, we show that YAP facilitates embryonic neural stem cell pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8c73a4cc9804a67b9449899b9c5e84
https://pubmed.ncbi.nlm.nih.gov/32669047
https://pubmed.ncbi.nlm.nih.gov/32669047
Autor:
Dasol Han, Mookwang Kwon, Jin-Hyun Ahn, Ju Hyun Lee, Keejung Yoon, Sun Min Lee, Youngik Yoon, Jae Youl Cho, Hogyun Noh
Publikováno v:
Antiviral research. 183
Due to diverse pathogenic potentials, there is a growing need for anti-HCMV agents. In this study, we show that treatment with DAPT, a γ-secretase inhibitor (GSI), impairs HCMV replication as assessed by a progeny assay based on immunostaining. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906f8017c12a106776b3725ef5bccb01
https://pubmed.ncbi.nlm.nih.gov/32755660
https://pubmed.ncbi.nlm.nih.gov/32755660
Autor:
Sung-Hyun Byun, Keejung Yoon, Dasol Han, Samuel J. Pleasure, Juwan Kim, Mookwang Kwon, Jae Youl Cho
Publikováno v:
EMBO reports, vol 19, iss 11
Despite growing evidence linking Drosophila melanogaster tweety‐homologue 1 (Ttyh1) to normal mammalian brain development and cell proliferation, its exact role has not yet been determined. Here, we show that Ttyh1 is required for the maintenance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0fb8a19659ec921b878ba406a8d295
https://doi.org/10.15252/embr.201745472
https://doi.org/10.15252/embr.201745472
Autor:
Dasol Han, Soobong Ha, Soojeong Park, Mookwang Kwon, Inhee Kim, Wonil Oh, Keejung Yoon, Sung-Hyun Byun, Nayeon Lee, Dae-Hyuk Kweon, Hong Bae Jeon, Juwan Kim, Jae Youl Cho
Publikováno v:
Stem Cells and Development. 24:983-994
Creatine is a nitrogenous organic acid known to function in adenosine triphosphate (ATP) metabolism. Recent evidence indicates that creatine regulates the differentiation of mesenchymal stem cells (MSCs) in processes such as osteogenesis and myogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c4e0cd777458509b999af61c3f5e06
https://doi.org/10.1089/scd.2014.0130
https://doi.org/10.1089/scd.2014.0130
Autor:
Inhee Kim, Dasol Han, Soojeong Park, Keejung Yoon, Sung-Hyun Byun, Soobong Ha, Juwan Kim, Mookwang Kwon
Publikováno v:
Biochemical and Biophysical Research Communications. 458:110-116
Mammalian brain development is regulated by multiple signaling pathways controlling cell proliferation, migration and differentiation. Here we show that YAP/TAZ enhance embryonic neural stem cell characteristics in a cell autonomous fashion using div
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dea51f5a92818792ed8f6452a90d382
https://doi.org/10.1016/j.bbrc.2015.01.077
https://doi.org/10.1016/j.bbrc.2015.01.077
Autor:
Inhee Kim, Woo-Jae Chung, Dasol Han, Keejung Yoon, Sung-Hyun Byun, Mookwang Kwon, Jiwon Jang, J.M. Lee, Dae-Hyuk Kweon, Nayeon Lee, Soojeong Park, Juwan Kim, Soobong Ha, Jyhyun Ahn, Sun-Young Kim, Jae Youl Cho
Publikováno v:
Stem Cells and Development. 23:2841-2850
Notch has a broad range of regulatory functions in many developmental processes, including hematopoiesis, neurogenesis, and angiogenesis. Notch has several key functional regions such as the RBP-Jκ/CBF1 association module (RAM) domain, nuclear local
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88fb486b2c4efbe7a3d854ec837010d
https://doi.org/10.1089/scd.2014.0031
https://doi.org/10.1089/scd.2014.0031