Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Mookkan Prabakaran"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Mucosal immunity plays a critical role in the protection of teleost fish against infection, but mucosal immunoglobulin of important aquaculture species unique to Southeast Asia remained greatly understudied. In this study, the sequence of immunoglobu
Externí odkaz:
https://doaj.org/article/621346af0a2e484a9080bc934c769d53
Publikováno v:
Viruses, Vol 14, Iss 6, p 1195 (2022)
The poultry industry is the largest source of meat and eggs for human consumption worldwide. However, viral outbreaks in farmed stock are a common occurrence and a major source of concern for the industry. Mortality and morbidity resulting from an ou
Externí odkaz:
https://doaj.org/article/6bd1053110b0411bbd9ab6fb2e4d763b
Autor:
Tasnim Saifudin Zakir, Tao Meng, Lee Ching Pei Carmen, Justin Jang Hann Chu, Raymond Tzer Pin Lin, Mookkan Prabakaran
Publikováno v:
Viruses, Vol 14, Iss 2, p 230 (2022)
The constant mutation of SARS-CoV-2 has led to the emergence of new variants, which call for urgent effective therapeutic interventions. The trimeric spike (S) protein of SARS-CoV-2 is highly immunogenic with the receptor-binding domain (RBD) that bi
Externí odkaz:
https://doaj.org/article/5eca232af3674fd5b24d84b0622d2f73
Autor:
Yishi Xu, Carla Bianca Luena Victorio, Qimei Ng, Mookkan Prabakaran, Yee-Joo Tan, Kaw Bing Chua
Publikováno v:
Emerging Microbes and Infections, Vol 5, Iss 1, Pp 1-11 (2016)
The Saffold virus (SAFV) genome is translated as a single long polyprotein precursor and co-translationally cleaved to yield 12 separate viral proteins. Little is known about the activities of SAFV proteins although their homologs in other picornavir
Externí odkaz:
https://doaj.org/article/82de74eaade74b30908c4ed5a895e684
Publikováno v:
Viruses, Vol 10, Iss 6, p 298 (2018)
Vaccination is an efficient way to prevent the occurrence of many infectious diseases in humans. To date, several viral vectors have been utilized for the generation of vaccines. Among them, baculovirus—categorized as a nonhuman viral vector—has
Externí odkaz:
https://doaj.org/article/65f9a3b100b144c79a8cd7e04c519d7d
Publikováno v:
Viruses, Vol 10, Iss 1, p 2 (2017)
The highly pathogenic avian influenza (HPAI) H5N1 virus remains to be one of the world’s largest pandemic threats due to the emergence of new variants. The rapid evolution of new sub-lineages is currently the greatest challenge in vaccine developme
Externí odkaz:
https://doaj.org/article/00f283ba12cd4ac5afa81b9947ce0e4f
Autor:
Subaschandrabose Rajesh Kumar, Mookkan Prabakaran, Kattur Venkatachalam Ashok Raj, Fang He, Jimmy Kwang
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128940 (2015)
Avian influenza A H7N7/NL/219/03 virus creates a serious pandemic threat to human health because it can transmit directly from domestic poultry to humans and from human to human. Our previous vaccine study reported that mice when immunized intranasal
Externí odkaz:
https://doaj.org/article/2a25559a70014396a013e9213af6d597
Autor:
Mookkan Prabakaran, Sonja Leyrer, Fang He, Sebastian Auer, Subaschandrabose R Kumar, Kathrin Kindsmueller, Nutan Mytle, Joerg Schneider, Stephen Lockhart, Jimmy Kwang
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107316 (2014)
The rapid evolution of new sublineages of H5N1 influenza poses the greatest challenge in control of H5N1 infection by currently existing vaccines. To overcome this, an MVAtor vector expressing three H5HA antigens A/Vietnam/1203/04, A/Indonesia/669/06
Externí odkaz:
https://doaj.org/article/15c8c13a432546d1b3517bbcbe5b79cc
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55536 (2013)
BACKGROUND: Human enterovirus 71 (HEV71) is one of the major pathogen responsible for hand, foot and mouth disease (HFMD). Currently no effective vaccine or antiviral drugs are available. Like poliovirus, EV71 is transmitted mainly by the feco-oral r
Externí odkaz:
https://doaj.org/article/eaf13f1889d340c9aa3def122d7dbf5c
Publikováno v:
Viruses, Vol 8, Iss 2, p 24 (2016)
Saffold Virus (SAFV) is a human cardiovirus that has been suggested to cause severe infection of the central nervous system (CNS). Compared to a similar virus, Theiler’s murine encephalomyelitis virus (TMEV), SAFV has a truncated Leader (L) protein
Externí odkaz:
https://doaj.org/article/c35aefe189a64fcd82a0747ec264c259