Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Moo J, Cho"'
Publikováno v:
CISP-BMEI
A major component of risk management during deep sedation or anesthesia involves the monitoring of various physiological signals. The aim of this study was to develop a sensing module for monitoring breathing sounds from trachea in order to minimize
Publikováno v:
Advanced Drug Delivery Reviews. 65:1331-1339
Many drugs have decreased therapeutic activity due to issues with absorption, distribution, metabolism and excretion. The co-formulation or covalent attachment of drugs with fatty acids has demonstrated some capacity to overcome these issues by impro
Autor:
Dae-Jin Yun, Vojislava Grbic, Hyun Jin Chun, Markus Schmid, François Godard, Min C. Kim, Detlef Weigel, Oliver Bracko, Kyoung Mi Park, Sureshkumar Balasubramanian, Moo J. Cho, Mi S. Park, Rebecca Schwab, Jun S. Seo, Sung C. Koo, Sang Yup Lee
Publikováno v:
The Plant Journal. 62:807-816
MADS-domain transcription factors play pivotal roles in various developmental processes. The lack of simple loss-of-function phenotypes provides impediments to understand the biological function of some of the MADS-box transcription factors. Here we
Autor:
Moo J. Cho, Aravind Asokan
Publikováno v:
Journal of Controlled Release. 106:146-153
Drug carriers containing weak acids or bases can promote cytosolic delivery of macromolecules by exploiting the acidic pH of the endosome. We have prepared two pH-sensitive mono-stearoyl derivatives of morpholine, one with a (2-hydroxy) propylene (ML
Publikováno v:
Pharmaceutical Research. 22:122-127
To understand the structural requirements in designing epitope-bearing oligonucleotides with high antibody-binding affinity.Binding affinity (KA) and stoichiometry (n) of dinitrophenyl (DNP)-derivatized model 27-mer oligonucleotides (ODNs), GGG(AAA)7
Autor:
Mirielle Adam, Moo J. Cho, Peter Sazani, Richard Jude Samulski, Joseph M. DeSimone, Karen McAllister, Michael Rubinstein
Publikováno v:
Journal of the American Chemical Society. 124:15198-15207
Polymeric nanogel vectors were developed for cellular gene and antisense delivery. Inverse microemulsion polymerization was utilized to synthesize biocompatible nanogels with controlled size, morphology, and composition. The chemical composition, siz
Autor:
Aravind Asokan, Moo J. Cho
Publikováno v:
Journal of Pharmaceutical Sciences. 91:903-913
Most cellular components such as the cytoplasm, endosomes, lysosomes, endoplasmic reticulum, Golgi bodies, mitochondria, and nuclei are known to maintain their own characteristic pH values. These pH values range from as low as 4.5 in the lysosome to
Autor:
Hae W. Yoon, Min C. Kim, Moo J. Cho, Hyeong Cheol Park, Judith Müller, Candace E. Elliott, Ralph Panstruga, Paul Schulze-Lefert, Alessandra Devoto
Publikováno v:
Nature. 416:447-451
In plants, defence against specific isolates of a pathogen can be triggered by the presence of a corresponding race-specific resistance gene1, whereas resistance of a more broad-spectrum nature can result from recessive, presumably loss-of-regulatory
Autor:
Moo J. Cho, Bruce N. Rehlaender
Publikováno v:
Pharmaceutical Research. 18:753-760
Purpose. To evaluate the potential use of antibodies as a carrier for monovalent protein haptens.
Publikováno v:
Pharmaceutical Research. 16:494-502
This review critically examines current understanding of the kinetics and biodistribution of antisense oligonucleotides, both at the cellular level and at the level of the intact organism. The pharmacodynamic relationships between biodistribution and