Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers

Autor: Viens Patrice, Zemmour Christophe, Finetti Pascal, Geneix Jeannine, Esterni Benjamin, Gelsi-Boyer Véronique, Monville Florence, Cervera Nathalie, Ginestier Christophe, Sircoulomb Fabrice, Letessier Anne, Charafe-Jauffret Emmanuelle, Jacquemier Jocelyne, Birnbaum Daniel, Chaffanet Max

Publikováno v: BMC Cancer, Vol 6, Iss 1, p 245 (2006)

Abstract Background Oncogene amplification and overexpression occur in tumor cells. Amplification status may provide diagnostic and prognostic information and may lead to new treatment strategies. Chromosomal regions 8p12, 8q24, 11q13, 17q12 and 20q1

Externí odkaz: https://doaj.org/article/b9460cb0ab6b43c9ab2a59e96dfeebd5

Comprehensive biomarkers analysis to explain resistances to PD1-L1 ICIs: The precision immuno-oncology for advanced non-small cell lung cancer (PIONeeR) trial

Autor: Greillier, Laurent, Monville, Florence, Leca, Vanina, Vely, Frédéric, Garcia, Stephane, Ciccolini, Joseph, Sabatier, Florence, Ferrani, Gilbert, Boudai, Nawel, Ghezali, Lamia, Landri, Marcellin, Marin, Clémence, Hamimed, Mourad, Arnaud, Laurent, Karlsen, Melanie, Atsou, Kevin, Bokobza, Sivan, Fleury, Pauline, Boyer, Arnaud, Audigier-Valette, Clarisse, Martinez, Stéphanie, Pegliasco, Hervé, Ray, Patrice, Falchero, Lionel, Serre, Antoine, Cloarec, Nicolas, Lebas, Louisiane, Hominal, Stephane, Barre, Patricia, Zahi, Sarah, Frikha, Ahmed, Bory, Pierre, Ray, Maryannick Le, Laborde, Lilian, Martin, Virginie, Malkoun, Richard, Roumieux, Marie, Mazieres, Julien, Perol, Maurice, Vivier, Eric, Benzekry, Sébastien, Fieschi, Jacques, Barlesi, Fabrice

Publikováno v: Cancer Research
AACR
AACR, Apr 2022, New Orleans, United States. pp.LB120, ⟨10.1158/1538-7445.AM2022-LB120⟩

International audience; Abstract Background: Resistance to PD1/L1 immune checkpoint inhibitors (ICIs) in advanced NSCLC patients is observed in about 80% of individuals with no robust predictive biomarker yet. The PIONeeR trial (NCT03493581) aims to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::59fe0213bcc36291abf3c7f7805d54b9
https://hal.inria.fr/hal-03926538

Immunogram to decipher PD1/L1 ICI resistance: a proof of concept in advanced Non-small cell lung cancer patients of the PIONeeR Project

Autor: Monville, Florence, Vely, Frederic, Ciccolini, Joseph, Sabatier, Florence, Garcia, Stephane, Leca, Vanina, Fabre, Marion, Piperoglou, Christelle, Outters, Pernelle, Arnaud, Laurent, Vanhille, Laurent, Lauge, Caroline, Martirosyan, Anna, Collignon, Aurelie, Roumieux, Marie, Mazieres, Julien, Perol, Maurice, Dignat-George, Francoise, Eric Vivier, Barlesi, Fabrice, Fieschi, Jacques

Publikováno v: Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer, BMJ Publishing Group 2019, 7 (1), p117
Web of Science
Journal for Immunotherapy of Cancer, 2019, 7 (1), p117

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c70beafd4c8d62a1abcdbedf5c8eb675
https://hal-amu.archives-ouvertes.fr/hal-02863942

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Stem cells and epithelial cancers: the example of breast cancer

Autor: Charafe-Jauffret, Emanuelle, Ginestier, Christophe, Monville, Florence, Wicinski, Julien, Bertucci, François, Viens, Patrice, Xerri, Luc, Cabaud, Olivier, Dontu, Gabriela, Wicha, Max S., Birnbaum, Daniel

Publikováno v: Annales de Pathologie
Annales de Pathologie, 2008, 28, pp.S30-S32. ⟨10.1016/j.annpat.2008.09.005⟩
Annales de Pathologie, Elsevier Masson, 2008, 28, pp.S30-S32. ⟨10.1016/j.annpat.2008.09.005⟩

International audience; no abstract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::af3f626bb49458fc09bdc7530de978bc
https://hal.science/hal-01431960