Zobrazeno 1 - 10
of 973
pro vyhledávání: '"Montserrat Garcia"'
Autor:
Jie Ping, Guochong Jia, Qiuyin Cai, Xingyi Guo, Ran Tao, Christine Ambrosone, Dezheng Huo, Stefan Ambs, Mollie E. Barnard, Yu Chen, Montserrat Garcia-Closas, Jian Gu, Jennifer J. Hu, Esther M. John, Christopher I. Li, Katherine Nathanson, Barbara Nemesure, Olufunmilayo I. Olopade, Tuya Pal, Michael F. Press, Maureen Sanderson, Dale P. Sandler, Toshio Yoshimatsu, Prisca O. Adejumo, Thomas Ahearn, Abenaa M. Brewster, Anselm J. M. Hennis, Timothy Makumbi, Paul Ndom, Katie M. O’Brien, Andrew F. Olshan, Mojisola M. Oluwasanu, Sonya Reid, Song Yao, Ebonee N. Butler, Maosheng Huang, Atara Ntekim, Bingshan Li, Melissa A. Troester, Julie R. Palmer, Christopher A. Haiman, Jirong Long, Wei Zheng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract African-ancestry (AA) participants are underrepresented in genetics research. Here, we conducted a transcriptome-wide association study (TWAS) in AA female participants to identify putative breast cancer susceptibility genes. We built geneti
Externí odkaz:
https://doaj.org/article/b9834eb3a0344dc2a7b7b629b0f35afc
Autor:
Naomie Olivos, Jim E. Banta, Rhonda Spencer-Hwang, Daniel Ansong, Laura E. Beane Freeman, Joe-Nat Clegg-Lamptey, Beatrice Wiafe-Addai, Lawrence Edusei, Ernest Adjei, Nicholas Titiloye, Florence Dedey, Francis Aitpillah, Joseph Oppong, Verna Vanderpuye, Ernest Osei-Bonsu, Thomas U. Ahearn, Richard Biritwum, Joel Yarney, Baffour Awuah, Kofi Nyarko, Montserrat Garcia-Closas, Mustapha Abubakar, Louise A. Brinton, Jonine D. Figueroa, Seth Wiafe
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Epidemiologic data on insecticide exposures and breast cancer risk are inconclusive and mostly from high-income countries. Using data from 1071 invasive pathologically confirmed breast cancer cases and 2096 controls from the Ghana Breast Hea
Externí odkaz:
https://doaj.org/article/94b2953df8c247bb8cf4915736b18174
Autor:
Hormuzd A. Katki, Sonja I. Berndt, Mitchell J. Machiela, Douglas R. Stewart, Montserrat Garcia-Closas, Jung Kim, Jianxin Shi, Kai Yu, Nathaniel Rothman
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background The rule of thumb that there is little gain in statistical power by obtaining more than 4 controls per case, is based on type-1 error α = 0.05. However, association studies that evaluate thousands or millions of associations use
Externí odkaz:
https://doaj.org/article/bd7386a1b9c44bb5b7f00af13cfc3223
Autor:
Elle S. Kim, Robert B. Scharpf, Montserrat Garcia-Closas, Kala Visvanathan, Victor E. Velculescu, Nilanjan Chatterjee
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-7 (2023)
Abstract Our proof-of-concept study reveals the potential of risk stratification by the combined effects of age, polygenic risk scores (PRS), and non-genetic risk factors in increasing the risk-benefit balance of rapidly emerging non-invasive multica
Externí odkaz:
https://doaj.org/article/bde85f08b8884f9a91692c4aa0947e36
Autor:
Hela Koka, Clara Bodelon, Steve Horvath, Priscilla Ming Yi Lee, Difei Wang, Lei Song, Tongwu Zhang, Amber N. Hurson, Jennifer Lyn Guida, Bin Zhu, Maeve Bailey-Whyte, Feng Wang, Cherry Wu, Koon Ho Tsang, Yee-Kei Tsoi, W. C. Chan, Sze Hong Law, Ray Ka Wai Hung, Gary M. Tse, Karen Ka-wan Yuen, Eric Karlins, Kristine Jones, Aurelie Vogt, Amy Hutchinson, Belynda Hicks, Montserrat Garcia-Closas, Stephen Chanock, Jill Barnholtz-Sloan, Lap Ah Tse, Xiaohong R. Yang
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Few studies have examined epigenetic age acceleration (AA), the difference between DNA methylation (DNAm) predicted age and chronological age, in relation to somatic genomic features in paired cancer and normal tissue, with less w
Externí odkaz:
https://doaj.org/article/26004ade06e44b32b2c9dc4cc4986412
Autor:
Mitchell J. Machiela, Wen-Yi Huang, Wendy Wong, Sonja I. Berndt, Joshua Sampson, Jonas De Almeida, Mustapha Abubakar, Jada Hislop, Kai-Ling Chen, Casey Dagnall, Norma Diaz-Mayoral, Mary Ferrell, Michael Furr, Alex Gonzalez, Belynda Hicks, Aubrey K. Hubbard, Amy Hutchinson, Kevin Jiang, Kristine Jones, Jia Liu, Erikka Loftfield, Jennifer Loukissas, Jerome Mabie, Shannon Merkle, Eric Miller, Lori M. Minasian, Ellen Nordgren, Brian Park, Paul Pinsky, Thomas Riley, Lorena Sandoval, Neeraj Saxena, Aurelie Vogt, Jiahui Wang, Craig Williams, Patrick Wright, Meredith Yeager, Bin Zhu, Claire Zhu, Stephen J. Chanock, Montserrat Garcia-Closas, Neal D. Freedman
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-12 (2023)
Abstract The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial is a prospective cohort study of nearly 155,000 U.S. volunteers aged 55–74 at enrollment in 1993–2001. We developed the PLCO Atlas Project, a large resource for mul
Externí odkaz:
https://doaj.org/article/18e9cf5db56e4fb2a19dac1e5bed4a75
Autor:
Pierre-Antoine Dugué, Clara Bodelon, Felicia F. Chung, Hannah R. Brewer, Srikant Ambatipudi, Joshua N. Sampson, Cyrille Cuenin, Veronique Chajès, Isabelle Romieu, Giovanni Fiorito, Carlotta Sacerdote, Vittorio Krogh, Salvatore Panico, Rosario Tumino, Paolo Vineis, Silvia Polidoro, Laura Baglietto, Dallas English, Gianluca Severi, Graham G. Giles, Roger L. Milne, Zdenko Herceg, Montserrat Garcia-Closas, James M. Flanagan, Melissa C. Southey
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-9 (2022)
Abstract Background DNA methylation in blood may reflect adverse exposures accumulated over the lifetime and could therefore provide potential improvements in the prediction of cancer risk. A substantial body of research has shown associations betwee
Externí odkaz:
https://doaj.org/article/3d246a97622448d390bd92141db5bf5a
Autor:
Zeni Wu, Ruth M. Pfeiffer, Doratha A. Byrd, Yunhu Wan, Daniel Ansong, Joe-Nat Clegg-Lamptey, Beatrice Wiafe-Addai, Lawrence Edusei, Ernest Adjei, Nicholas Titiloye, Florence Dedey, Francis Aitpillah, Joseph Oppong, Verna Vanderpuye, Ernest Osei-Bonsu, Casey L. Dagnall, Kristine Jones, Amy Hutchinson, Belynda D. Hicks, Thomas U. Ahearn, Rob Knight, Richard Biritwum, Joel Yarney, Seth Wiafe, Baffour Awuah, Kofi Nyarko, Montserrat Garcia-Closas, Rashmi Sinha, Jonine D. Figueroa, Louise A. Brinton, Britton Trabert, Emily Vogtmann
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT The human fecal and oral microbiome may play a role in the etiology of breast cancer through modulation of endogenous estrogen metabolism. This study aimed to investigate associations of circulating estrogens and estrogen metabolites with th
Externí odkaz:
https://doaj.org/article/7910c0285efa4e909fd0c1af4c22781f
Autor:
Isabel Graupera, Maja Thiele, Ann T. Ma, Miquel Serra-Burriel, Judit Pich, Núria Fabrellas, Llorenç Caballeria, Robert J. de Knegt, Ivica Grgurevic, Mathias Reichert, Dominique Roulot, Jörn M. Schattenberg, Juan M. Pericas, Paolo Angeli, Emmanuel A. Tsochatzis, Indra Neil Guha, Montserrat Garcia-Retortillo, Rosa M. Morillas, Rosario Hernández, Jordi Hoyo, Matilde Fuentes, Anita Madir, Adrià Juanola, Anna Soria, Marta Juan, Marta Carol, Alba Diaz, Sönke Detlefsen, Pere Toran, Guillem Pera, Céline Fournier, Anne Llorca, Phillip N. Newsome, Michael Manns, Harry J. de Koning, Feliu Serra-Burriel, Fernando Cucchietti, Anita Arslanow, Marko Korenjak, Laurens van Kleef, Josep Lluis Falcó, Patrick S. Kamath, Tom H. Karlsen, Laurent Castera, Frank Lammert, Aleksander Krag, Pere Ginès, for the LiverScreen Consortium investigators
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background The development of liver cirrhosis is usually an asymptomatic process until late stages when complications occur. The potential reversibility of the disease is dependent on early diagnosis of liver fibrosis and timely targeted tre
Externí odkaz:
https://doaj.org/article/190002eb7b394df3af13c8d603576ee0
Autor:
Amber N. Hurson, Mustapha Abubakar, Alina M. Hamilton, Kathleen Conway, Katherine A. Hoadley, Michael I. Love, Andrew F. Olshan, Charles M. Perou, Montserrat Garcia-Closas, Melissa A. Troester
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract TP53 and estrogen receptor (ER) are essential in breast cancer development and progression, but TP53 status (by DNA sequencing or protein expression) has been inconsistently associated with survival. We evaluated whether RNA-based TP53 class
Externí odkaz:
https://doaj.org/article/529696f68a5e470a94d527f453ee537a