Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Montserrat, Andreu"'
Autor:
Maria Gonzalez-Vivo, Minna K. Lund Tiirikainen, Montserrat Andreu, Agnes Fernandez-Clotet, Alicia López-García, Francisca Murciano Gonzalo, Lourdes Abril Rodriguez, Carmen de Jesús-Gil, Ester Ruiz-Romeu, Lídia Sans-de San Nicolàs, Lluis F. Santamaria-Babí, Lucía Márquez-Mosquera
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundVedolizumab is a humanized monoclonal antibody targeting the α4β7 integrin used for the treatment of ulcerative colitis. Few biomarkers related to vedolizumab response have been identified. The aim of this work was to assess whether basel
Externí odkaz:
https://doaj.org/article/4bd969502cc64794b7b0b9b1956b7e70
Autor:
Fausto Riu Pons, Montserrat Andreu, Dolores Naranjo, Marco Antonio Álvarez-González, Agustín Seoane, Josep Maria Dedeu, Luis Barranco, Xavier Bessa
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background It is unknown whether narrow-band imaging (NBI) could be more effective than high-definition white-light endoscopy (HD-WLE) in detecting serrated lesions in patients with prior serrated lesions > 5 mm not completely fulfilling ser
Externí odkaz:
https://doaj.org/article/d834902e259f4e3d84188af2041baecb
Autor:
Erika López-Arribillaga, Bing Yan, Teresa Lobo-Jarne, Yolanda Guillén, Silvia Menéndez, Montserrat Andreu, Anna Bigas, Mar Iglesias, Lluís Espinosa
Publikováno v:
Cells, Vol 10, Iss 11, p 2928 (2021)
Background: Previous studies in mice indicated that Paneth cells and c-Kit-positive goblet cells represent the stem cell niche of the small intestine and colon, respectively, partly by supporting Wnt and Notch activation. Whether these cell populatio
Externí odkaz:
https://doaj.org/article/a2b2abc47bf94a33859ea7afe20bbba6
Autor:
Ajay Goel, C. Richard Boland, Antoni Castells, Xavier Llor, Montserrat Andreu, Francesc Balaguer, Cristina Alenda, Estefania Rojas, Eva Hernández-Illán, Miriam Juárez, Lucia Perez-Carbonell, Cecilia Egoavil, Rodrigo Jover, Oscar Murcia
Purpose: A recent study reported that 5-fluorouracil (5-FU)-based chemotherapy is less effective in treating patients with advanced colorectal cancer demonstrating hypermethylation of the TFAP2E gene. The aim of our study was to confirm and validate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64dbea501a83cf50f8b529096f5ce5b8
https://doi.org/10.1158/1078-0432.c.6525716.v1
https://doi.org/10.1158/1078-0432.c.6525716.v1
Autor:
Ajay Goel, C. Richard Boland, Antoni Castells, Xavier Llor, Montserrat Andreu, Francesc Balaguer, Cristina Alenda, Estefania Rojas, Eva Hernández-Illán, Miriam Juárez, Lucia Perez-Carbonell, Cecilia Egoavil, Rodrigo Jover, Oscar Murcia
Supplementary Figure 4. Epicolon I. Overall Survival Stage IV Patients: TFAP2E IHC Expression. Disease Free Survival Stage II and III Patients: TFAP2E IHC Expression. (A) Overall survival of patients with stage IV disease, according to TFAP2E express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c18a5718bed4aba2394cfb10756257d
https://doi.org/10.1158/1078-0432.22464425
https://doi.org/10.1158/1078-0432.22464425
Autor:
Ajay Goel, C. Richard Boland, Antoni Castells, Xavier Llor, Montserrat Andreu, Francesc Balaguer, Cristina Alenda, Estefania Rojas, Eva Hernández-Illán, Miriam Juárez, Lucia Perez-Carbonell, Cecilia Egoavil, Rodrigo Jover, Oscar Murcia
Supplementary Figure 3. Correlation between TFAP2E intron 3 methylation and IHC expression. When methylation was analysed as a continuous variable using linear regression analysis, we observed a trend towards negative correlation with IHC protein exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401cff78e7eb3cedf405838fb60cafba
https://doi.org/10.1158/1078-0432.22464428
https://doi.org/10.1158/1078-0432.22464428
Autor:
Ajay Goel, C. Richard Boland, Antoni Castells, Xavier Llor, Montserrat Andreu, Francesc Balaguer, Cristina Alenda, Estefania Rojas, Eva Hernández-Illán, Miriam Juárez, Lucia Perez-Carbonell, Cecilia Egoavil, Rodrigo Jover, Oscar Murcia
Supplementary data Supplementary Methods Supplementary Table 1. Characteristics of Epicolon I patients (n=532) Supplementary Table 2. Characteristics of Clinical cohort patients (n=251) Supplementary Table 3. Primer sequences Supplementary Figure 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a32c0f927b95957ba14fa43bf37bed3
https://doi.org/10.1158/1078-0432.22464437.v1
https://doi.org/10.1158/1078-0432.22464437.v1
Autor:
Ajay Goel, C. Richard Boland, Antoni Castells, Xavier Llor, Montserrat Andreu, Francesc Balaguer, Cristina Alenda, Estefania Rojas, Eva Hernández-Illán, Miriam Juárez, Lucia Perez-Carbonell, Cecilia Egoavil, Rodrigo Jover, Oscar Murcia
Supplementary Figure 1. Schematic representation of TFAP2E gene. The gene encoding transcription factor AP-2 epsilon (TFAP2E) is located on chromosome 1p34. In the schematic overview, exons are represented by blue boxes and introns with blue lines. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b4db557cc7027a8164e014566fe1b8
https://doi.org/10.1158/1078-0432.22464422
https://doi.org/10.1158/1078-0432.22464422
Autor:
Ajay Goel, C. Richard Boland, Antoni Castells, Xavier Llor, Montserrat Andreu, Francesc Balaguer, Cristina Alenda, Estefania Rojas, Eva Hernández-Illán, Miriam Juárez, Lucia Perez-Carbonell, Cecilia Egoavil, Rodrigo Jover, Oscar Murcia
Supplementary Figure 2. Methylation analysis of TFAP2E CpG islands in CRC tissues. Calculation of cutoff value of TFAP2E Intron 3 methylation. Results comparing methylation of the TFAP2E CpG1 (Promoter/Exon 1) and CpG2 (Intron 3) in CRC tissues (N=50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a934f2e61084649743df358d5f1f4f3b
https://doi.org/10.1158/1078-0432.22464434
https://doi.org/10.1158/1078-0432.22464434
Autor:
Silvio Danese, Jean-Frederic Colombel, Milan Lukas, Javier P Gisbert, Geert D'Haens, Bu'hussain Hayee, Remo Panaccione, Hyun-Soo Kim, Walter Reinisch, Helen Tyrrell, Young S Oh, Swati Tole, Akiko Chai, Kirsten Chamberlain-James, Meina Tao Tang, Stefan Schreiber, Nazimuddin Aboo, Tariq Ahmad, Xavier Aldeguer Mante, Matthieu Allez, Sven Almer, Romain Altwegg, Montserrat Andreu Garcia, Ramesh Arasaradnam, Sandro Ardizzone, Alessandro Armuzzi, Ian Arnott, Guy Aumais, Irit Avni-Biron, Peter Barrow, Ian Beales, Fernando Bermejo San Jose, Abraham Bezuidenhout, Livia Biancone, Michael Blaeker, Stuart Bloom, Bernd Bokemeyer, Fabrizio Bossa, Peter Bossuyt, Guillaume Bouguen, Yoram Bouhnik, Gerd Bouma, Raymond Bourdages, Arnaud Bourreille, Christian Boustiere, Tomas Brabec, Stephan Brand, Carsten Buening, Anthony Buisson, Guillaume Cadiot, Xavier Calvet Calvo, Franck Carbonnel, Daniel Carpio, Jae Hee Cheon, Naoki Chiba, Camelia Chioncel, Nicoleta-Claudia Cimpoeru, Martin Clodi, Gino Roberto Corazza, Rocco Cosintino, Jose Cotter, Thomas Creed, Fraser Cummings, Gian Luigi de' Angelis, Marc De Maeyer, Milind Desai, Etienne Desilets, Pierre Desreumaux, Olivier Dewit, Johanna Dinter, Ecaterina Daniela Dobru, Tomas Douda, Dan Lucian Dumitrascu, Matthias Ebert, Ana Echarri Piudo, Magdy Elkhashab, Chang Soo Eun, Brian Feagan, Roland Fejes, Catarina Fidalgo, Sigal Fishman, Bernard Flourié, Sharyle Fowler, Walter Fries, Csaba Fulop, Mathurin Fumery, Gyula G Kiss, Sonja Gassner, Daniel Gaya, Bastianello Germanà, Liliana Simona Gheorghe, Cyrielle Gilletta de Saint Joseph, Paolo Gionchetti, Adrian-Eugen Goldis, Raquel Gonçalves, Jean-Charles Grimaud, Tibor Gyökeres, Herve Hagege, Andrei Haidar, Heinz Hartmann, Peter Hasselblatt, Buhussain Hayee, Xavier Hebuterne, Per Hellström, Pieter Hindryckx, Helena Hlavova, Frank Hoentjen, Stefanie Howaldt, Ludek Hrdlicka, Kyu Chan Huh, Maria Isabel Iborra Colomino, Florentina Ionita-Radu, Peter Irving, Jørgen Jahnsen, ByungIk Jang, Jeroen Jansen, Seong Woo Jeon, Rodrigo Jover Martinez, Pascal Juillerat, Per Karlén, Arthur Kaser, Radan Keil, Deepak Kejariwal, Dan Keret, Reena Khanna, Dongwoo Kim, Duk Hwan Kim, Hyo-Jong Kim, Joo Sung Kim, Kueongok Kim, Kyung-Jo Kim, Sung Kook Kim, Young-Ho Kim, Jochen Klaus, Anna Kohn, Vladimir Kojecky, Ja Seol Koo, Robert Kozak, Milan Kremer, Tunde Kristof, Frederik Kruger, David Laharie, Adi Lahat-zok, Evgeny Landa, Jonghun Lee, Kang-Moon Lee, Kook Lae Lee, YooJin Lee, Frank Lenze, Wee Chian Lim, Jimmy Limdi, James Lindsay, Pilar Lopez Serrano, Edouard Louis, Stefan Lueth, Giovanni Maconi, Fazia Mana, Steven Mann, John Mansfield, Santino Marchi, Marco Marino, John Marshall, Maria Dolores Martin Arranz, Radu-Bogdan Mateescu, John McLaughlin, Simon McLaughlin, Ehud Melzer, Jessica Mertens, Paul Mitrut, Tamas Molnar, Vinciane Muls, Pushpakaran Munuswamy, Charles Murray, Timna Naftali, Visvakuren Naidoo, Yusuf Nanabhay, Lucian Negreanu, Augustin Nguyen, Thomas Ochsenkuehn, Ambrogio Orlando, Julian Panes Diaz, Maya Paritsky, Dong Il Park, Jihye Park, Luca Pastorelli, Markus Peck-Radosavljevic, Farhad Peerani, Javier Perez Gisbert, Laurent Peyrin-Biroulet, Laurence Picon, Marieke Pierik, Terry Ponich, Francisco Portela, Maartens Jeroen Prins, Istvan Racz, Khan Fareed Rahman, Jean-Marie Reimund, Max Reinshagen, Xavier Roblin, Rodolfo Rocca, Francesca Rogai, Gerhard Rogler, Agnes Salamon, Ennaliza Salazar, Zoltan Sallo, Sunil Samuel, Miquel de los Santos Sans Cuffi, Edoardo Vincenzo Savarino, Vincenzo Savarino, Guillaume Savoye, Andrada Seicean, Christian Selinger, David Martins Serra, Hang Hock Shim, SungJae Shin, Britta Siegmund, Jesse Siffledeen, Wayne Simmonds, Jan Smid, Jose Sollano, Geun Am Song, Alexander Speight, Ioan Sporea, Dirk Staessen, George Stancu, Alan Steel, David Stepek, Victor Stoica, Andreas Sturm, Gyorgy Szekely, Teck Kiang Tan, Carlos Taxonera Samso, John Thomson, Michal Tichy, Gabor Tamas Toth, Zsolt Tulassay, Marcello Vangeli, Marta Varga, Ana Vieira, Stephanie Viennot, Erica Villa, Petr Vitek, Harald Vogelsang, Petr Vyhnalek, Peter Wahab, Jens Walldorf, Byong Duk Ye, Christopher Ziady
Publikováno v:
Lancet Gastroenterology & Hepatology, 7, 118-127
Lancet Gastroenterology & Hepatology, 7, 2, pp. 118-127
Lancet Gastroenterology & Hepatology, 7, 2, pp. 118-127
Item does not contain fulltext BACKGROUND: Etrolizumab is a gut-targeted anti-β7 integrin monoclonal antibody. In a previous phase 2 induction study, etrolizumab significantly improved clinical remission versus placebo in patients with moderately to