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Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.

Autor: Park YJ; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA., Pinto D; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Walls AC; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA., Liu Z; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., De Marco A; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Benigni F; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Zatta F; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Silacci-Fregni C; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Bassi J; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Sprouse KR; Department of Biochemistry, University of Washington, Seattle, WA, USA., Addetia A; Department of Biochemistry, University of Washington, Seattle, WA, USA., Bowen JE; Department of Biochemistry, University of Washington, Seattle, WA, USA., Stewart C; Department of Biochemistry, University of Washington, Seattle, WA, USA., Giurdanella M; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Saliba C; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Guarino B; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Schmid MA; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Franko NM; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA., Logue JK; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA., Dang HV; Vir Biotechnology, San Francisco, CA, USA., Hauser K; Vir Biotechnology, San Francisco, CA, USA., di Iulio J; Vir Biotechnology, San Francisco, CA, USA., Rivera W; Vir Biotechnology, San Francisco, CA, USA., Schnell G; Vir Biotechnology, San Francisco, CA, USA., Rajesh A; Vir Biotechnology, San Francisco, CA, USA., Zhou J; Vir Biotechnology, San Francisco, CA, USA., Farhat N; Vir Biotechnology, San Francisco, CA, USA., Kaiser H; Vir Biotechnology, San Francisco, CA, USA., Montiel-Ruiz M; Vir Biotechnology, San Francisco, CA, USA., Noack J; Vir Biotechnology, San Francisco, CA, USA., Lempp FA; Vir Biotechnology, San Francisco, CA, USA., Janer J; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., Abdelnabi R; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium., Maes P; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium., Ferrari P; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.; Division of Nephrology, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Clinical School, University of New South Wales, Sydney, New South Wales, Australia., Ceschi A; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.; Clinical Trial Unit, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Division of Clinical Pharmacology and Toxicology, Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, Lugano, Switzerland.; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, Zurich, Switzerland., Giannini O; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.; Department of Medicine, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., de Melo GD; Institut Pasteur, Université Paris Cité, Lyssavirus Epidemiology and Neuropathology Unit, F-75015 Paris, France., Kergoat L; Institut Pasteur, Université Paris Cité, Lyssavirus Epidemiology and Neuropathology Unit, F-75015 Paris, France., Bourhy H; Institut Pasteur, Université Paris Cité, Lyssavirus Epidemiology and Neuropathology Unit, F-75015 Paris, France., Neyts J; KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium., Soriaga L; Vir Biotechnology, San Francisco, CA, USA., Purcell LA; Vir Biotechnology, San Francisco, CA, USA., Snell G; Vir Biotechnology, San Francisco, CA, USA., Whelan SPJ; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA., Lanzavecchia A; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Virgin HW; Vir Biotechnology, San Francisco, CA, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA., Piccoli L; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Chu HY; Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA., Pizzuto MS; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Corti D; Humabs Biomed SA, Subsidiary of Vir Biotechnology, Bellinzona, Switzerland., Veesler D; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2022 Nov 11; Vol. 378 (6620), pp. 619-627. Date of Electronic Publication: 2022 Oct 20.

Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape.

Autor: Starr TN; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Czudnochowski N; Vir Biotechnology, San Francisco, CA 94158, USA., Zatta F; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Park YJ; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Liu Z; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Addetia A; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Pinto D; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Beltramello M; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Hernandez P; Vir Biotechnology, San Francisco, CA 94158, USA., Greaney AJ; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA., Marzi R; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Glass WG; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Zhang I; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Tri-Institutional PhD Program in Computational Biology and Medicine, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., Dingens AS; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Bowen JE; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Wojcechowskyj JA; Vir Biotechnology, San Francisco, CA 94158, USA., De Marco A; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Rosen LE; Vir Biotechnology, San Francisco, CA 94158, USA., Zhou J; Vir Biotechnology, San Francisco, CA 94158, USA., Montiel-Ruiz M; Vir Biotechnology, San Francisco, CA 94158, USA., Kaiser H; Vir Biotechnology, San Francisco, CA 94158, USA., Tucker H; Vir Biotechnology, San Francisco, CA 94158, USA., Housley MP; Vir Biotechnology, San Francisco, CA 94158, USA., di Iulio J; Vir Biotechnology, San Francisco, CA 94158, USA., Lombardo G; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Agostini M; Vir Biotechnology, San Francisco, CA 94158, USA., Sprugasci N; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Culap K; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Jaconi S; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Meury M; Vir Biotechnology, San Francisco, CA 94158, USA., Dellota E; Vir Biotechnology, San Francisco, CA 94158, USA., Cameroni E; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Croll TI; Cambridge Institute for Medical Research, Department of Haematology, University of Cambridge, Cambridge, CB2 0XY, UK., Nix JC; Molecular Biology Consortium, Advanced Light Source, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Havenar-Daughton C; Vir Biotechnology, San Francisco, CA 94158, USA., Telenti A; Vir Biotechnology, San Francisco, CA 94158, USA., Lempp FA; Vir Biotechnology, San Francisco, CA 94158, USA., Pizzuto MS; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Chodera JD; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Hebner CM; Vir Biotechnology, San Francisco, CA 94158, USA., Whelan SPJ; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Virgin HW; Vir Biotechnology, San Francisco, CA 94158, USA.; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX 75390, USA., Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Corti D; Humabs BioMed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland., Bloom JD; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.; Howard Hughes Medical Institute, Seattle, WA 98109, USA., Snell G; Vir Biotechnology, San Francisco, CA 94158, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2021 Apr 08. Date of Electronic Publication: 2021 Apr 08.