Differential expression of CCR2 and CX3CR1 on CD16+ monocyte subsets is associated with asthma severity

Autor: Reem Al-Rashoudi, Gillian Moir, Mohamed S. Al-Hajjaj, Monther M. Al-Alwan, Heather M. Wilson, Isabel J. Crane

Publikováno v: Allergy, Asthma & Clinical Immunology, Vol 15, Iss 1, Pp 1-11 (2019)

Abstract Background Monocytes play an important role in immune and inflammatory diseases and monocyte subsets are predictors of disease in certain conditions. Expression of the chemokine receptors, CCR2 and CX3CR1 on monocyte subsets relates to their

Externí odkaz: https://doaj.org/article/c7bcd9c2630d41baa44d3a2e75f7c144

Severe Combined Immunodeficiency from a Homozygous DNA Ligase 1 Mutant with Reduced Catalytic Activity but Increased Ligation Fidelity.

Autor: Alajlan H; Translational Genomics, Centre for Genomic Medicine, King Faisal Specialist Hospital & Research Centre, MBC 3, P.O. Box 3354, 11211, Riyadh, Saudi Arabia., Raducanu VS; Bioscience Program, Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, 23955, Thuwal, Saudi Arabia., Lopez de Los Santos Y; Cell Migration and Signaling Laboratory, Bioscience Program, Division of Biological & Environmental Science & Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia., Tehseen M; Bioscience Program, Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, 23955, Thuwal, Saudi Arabia., Alruwaili H; Translational Genomics, Centre for Genomic Medicine, King Faisal Specialist Hospital & Research Centre, MBC 3, P.O. Box 3354, 11211, Riyadh, Saudi Arabia., Al-Mazrou A; Cell Therapy and Immunobiology Department, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia., Mohammad R; Pediatric Allergy & Immunology, Department of Pediatrics, King Faisal Specialist Hospital & Research Centre, MBC 3, P.O. Box 3354, 11211, Riyadh, Saudi Arabia., Al-Alwan M; Cell Therapy and Immunobiology Department, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., De Biasio A; Bioscience Program, Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, 23955, Thuwal, Saudi Arabia., Merzaban JS; Cell Migration and Signaling Laboratory, Bioscience Program, Division of Biological & Environmental Science & Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia., Al-Mousa H; Pediatric Allergy & Immunology, Department of Pediatrics, King Faisal Specialist Hospital & Research Centre, MBC 3, P.O. Box 3354, 11211, Riyadh, Saudi Arabia. hamoudalmousa@kfshrc.edu.sa.; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia. hamoudalmousa@kfshrc.edu.sa., Hamdan SM; Bioscience Program, Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, 23955, Thuwal, Saudi Arabia. samir.hamdan@kaust.edu.sa., Alazami AM; Translational Genomics, Centre for Genomic Medicine, King Faisal Specialist Hospital & Research Centre, MBC 3, P.O. Box 3354, 11211, Riyadh, Saudi Arabia. amalazami@kfshrc.edu.sa.

Publikováno v: Journal of clinical immunology [J Clin Immunol] 2024 Jun 19; Vol. 44 (7), pp. 151. Date of Electronic Publication: 2024 Jun 19.

A unique STK4 mutation truncating only the C-terminal SARAH domain results in a mild clinical phenotype despite severe T cell lymphopenia: Case report.

Autor: Al-Saud B; Section of Pediatric Allergy/Immunology, Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Alajlan H; Translational Genomics, Centre for Genomic Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Alruwaili H; Translational Genomics, Centre for Genomic Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Almoaibed L; Section of Pediatric Allergy/Immunology, Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia., Al-Mazrou A; Cell Therapy and Immunobiology Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Ghebeh H; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.; Cell Therapy and Immunobiology Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Al-Alwan M; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.; Cell Therapy and Immunobiology Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia., Alazami AM; Translational Genomics, Centre for Genomic Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Feb 01; Vol. 15, pp. 1329610. Date of Electronic Publication: 2024 Feb 01 (Print Publication: 2024).

Metabolic Alteration of MCF-7 Cells upon Indirect Exposure to E. coli Secretome: A Model of Studying the Microbiota Effect on Human Breast Tissue.

Autor: AlMalki RH; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia., Jaber MA; Pharmaceutical Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy and Medical Sciences, University of Petra, Amman 11196, Jordan., Al-Ansari MM; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia., Sumaily KM; Clinical Biochemistry Unit, Pathology Department, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia., Al-Alwan M; Cell Therapy and Immunobiology Department, King Faisal Specialist Hospital and Research Centre (KFSHRC), Riyadh 11211, Saudi Arabia., Sabi EM; Clinical Biochemistry Unit, Pathology Department, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia., Malkawi AK; Department of Chemistry and Biochemistry, Université Du Québec à Montréal, Montréal, QC H3C 3P8, Canada., Abdel Rahman AM; Metabolomics Section, Department of Clinical Genomics, Center for Genomics Medicine, King Faisal Specialist Hospital and Research Centre (KFSHRC), Riyadh 11211, Saudi Arabia.

Publikováno v: Metabolites [Metabolites] 2023 Aug 11; Vol. 13 (8). Date of Electronic Publication: 2023 Aug 11.

E. coli Secretome Metabolically Modulates MDA-MB-231 Breast Cancer Cells' Energy Metabolism.

Autor: AlMalki RH; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia., Sebaa R; Department of Medical Laboratories, College of Applied Medical Sciences, Shaqra University, Al-Dawadmi 17472, Saudi Arabia, Al-Ansari MM; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia., Al-Alwan M; Stem Cell and Tissue Re-Engineering Program, King Faisal Specialist Hospital and Research Centre (KFSHRC), Riyadh 11211, Saudi Arabia.; College of Medicine, Al-Faisal University, Riyadh 11533, Saudi Arabia., Alwehaibi MA; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia., Rahman AMA; Metabolomics Section, Department of Clinical Genomics, Center for Genomics Medicine, King Faisal Specialist Hospital and Research Centre (KFSHRC), Riyadh 11211, Saudi Arabia.; Department of Biochemistry and Molecular Medicine, College of Medicine, Al Faisal University, Riyadh 11533, Saudi Arabia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 20; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 20.