Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Monther F Mahdi"'
Publikováno v:
Journal of Advanced Pharmaceutical Technology & Research, Vol 14, Iss 3, Pp 213-219 (2023)
Lung cancer is the most common malignancy worldwide, with approximately 1.8 million new cases yearly. Cytotoxic drugs are frequently used in cancer treatment. Even though the medicine enhances patients' quality of life, several drawbacks diminish its
Externí odkaz:
https://doaj.org/article/5be226ce9b144751b520a7f16c4a357d
Autor:
Marwan I Jihad, Monther F Mahdi
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 15, Iss 6, Pp 1023-1026 (2023)
Cancer is a disease triggered by an uncontrolled growth of a group of cells usually from a single cell. Chemotherapy is a common and systematic therapy that involves the use of anticancer drugs also known as chemotherapeutical agents to treat cancer.
Externí odkaz:
https://doaj.org/article/86a08fcafd6a45aeb9bd5ab201bac810
Publikováno v:
Pharmacia, Vol 71, Iss , Pp 1-10 (2024)
This work studied the anti-breast cancer activities of pyrazoline-containing benzenesulfonamides (6–10) in vitro and silico. The GOLD suite performed molecular docking on the target human estrogen receptor and the PARPA1 antagonist crystal structur
Externí odkaz:
https://doaj.org/article/82591976a2924c698fa12f4f99de5e3a
Publikováno v:
Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 24, Iss 3 (2024)
A novel series of pyrazole, oxadiazole and thiadiazole bearing Nabumetone moiety were designed, synthesized, and evaluated for their anti-inflammatory activity against cyclooxygenase enzyme 2, after Insilico assay (by molecular docking study) a best
Externí odkaz:
https://doaj.org/article/45bd5d8613284b2ea50368238a1f76fb
Autor:
Samer Tareq Jasim, Monther F. Mahdi
Publikováno v:
Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 24, Iss 2 (2024)
New benzene sulfonamide compounds 4–10 was modeled at the molecular level to reveal binding opportunities, bond length, angle, and energy scores in the CA II, CAXII, and CAIX active sites. To test their cytotoxic effect against the AMJ-13 Iraqi bre
Externí odkaz:
https://doaj.org/article/2109f954bd214130b5b1625a380ca71c
Publikováno v:
Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 24, Iss 1 (2024)
Lung cancer is the most prevalent worldwide. In addition, it is also the most common cause of cancer-related deaths worldwide, with around 1.8 million new cases annually. With a 5-year survival rate of fewer than 20%. Cytotoxic medicines are common
Externí odkaz:
https://doaj.org/article/07b4760edc8244fcbb4c2481fc6ba864
Publikováno v:
Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 23, Iss 4 (2023)
New series of 4-aminophenyl quinazolinone attached to an aromatic aldehyde moiety has been designed. Compound (ZA) was synthesized by a reaction of benzene-1,4-diamine with 2-aminobenzoic acid. The reaction between (ZA) intermediate and different
Externí odkaz:
https://doaj.org/article/1d295273ff344305931d7e4dc60c7072
Publikováno v:
Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 23, Iss 3 (2023)
In this work the pharmacological study and synthesis of new thiadiazine bearing on triazole which obtained from hippuric acid , indomethacin and mefenamic acid that have carboxylic acid moiety, Drugs with carboxylic groups and thiocarbohydrazide inte
Externí odkaz:
https://doaj.org/article/be5bcd06990c47da88dcafcc1c1c5208
Publikováno v:
INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY. 12:1733-1741
A series of nine novel 4, 5-dihydro-1H- pyrazole-1-yl acetate derivatives (IVa-i) by Shahla et al. were investigated in-vitro for their ability to prohibit arachidonic acid (AA) from becoming prostaglandin H2 (PGH2), the inhibitory effects were found
Publikováno v:
Al-Mustansiriyah Journal of Pharmaceutical Sciences, Vol 20, Iss 2 (2020)
New compounds containing 4-thiazolidinone pharmacophore 5(a) and (5b) have been synthesized. The chemical structures of the intermediate and final compounds were characterized and confirmed by using FT-IR and 1H-NMR spectroscopy. All final compounds
Externí odkaz:
https://doaj.org/article/4ddbcf0691274bcfa7754385d35abe95