Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

Autor: Arloth, Janine, Bogdan, Ryan, Altmann, Andre, Lawson, William B, Lewis, Glyn, MacIntyre, Donald, Maier, Wolfgang, Mattheisen, Manuel, McGrath, Patrick J, McIntosh, Andrew, McLean, Alan, Middeldorp, Christel M, Middleton, Lefkos, Trümbach, Dietrich, Montgomery, Grant M, Murphy, Shawn N, Nauck, Matthias, Nolen, Willem A, Nyholt, Dale R, O'Donovan, Michael, Oskarsson, Högni, Pedersen, Nancy, Scheftner, William A, Schulz, Andrea, Wurst, Wolfgang, Schulze, Thomas G, Shyn, Stanley I, Sigurdsson, Engilbert, Slager, Susan L, Smit, Johannes H, Stefansson, Hreinn, Steffens, Michael, Thorgeirsson, Thorgeir, Tozzi, Federica, Treutlein, Jens, Mehta, Divya, Uhr, Manfred, van den Oord, Edwin J C G, Van Grootheest, Gerard, Völzke, Henry, Weilburg, Jeffrey B, Willemsen, Gonneke, Zitman, Frans G, Neale, Benjamin, Daly, Mark, Levinson, Douglas F, Sullivan, Patrick F, Klengel, Torsten, Erhardt, Angelika, Carey, Caitlin E, Conley, Emily Drabant, Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics, Weber, Peter, Ruepp, Andreas, Müller-Myhsok, Bertram, Hariri, Ahmad R, Binder, Elisabeth B, PGC, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Ripke, Stephan, Wray, Naomi R, Lewis, Cathryn M, Hamilton, Steven P, Weissman, Myrna M, Frishman, Goar, Breen, Gerome, Byrne, Enda M, Blackwood, Douglas H R, Boomsma, Dorret I, Cichon, Sven, Heath, Andrew C, Holsboer, Florian, Lucae, Susanne, Madden, Pamela A F, Martin, Nicholas G, Menke, Andreas, McGuffin, Peter, Muglia, Pierandrea, Noethen, Markus M, Penninx, Brenda P, Pergadia, Michele L, Potash, James B, Rietschel, Marcella, Lin, Danyu, Shi, Jianxin, Wagner, Klaus V, Steinberg, Stacy, Grabe, Hans J, Lichtenstein, Paul, Magnusson, Patrik, Perlis, Roy H, Preisig, Martin, Smoller, Jordan W, Stefansson, Kari, Uher, Rudolf, Kutalik, Zoltan, Balsevich, Georgia, Tansey, Katherine E, Teumer, Alexander, Viktorin, Alexander, Barnes, Michael R, Bettecken, Thomas, Breuer, René, Castro, Victor M, Churchill, Susanne E, Coryell, William H, Schmidt, Mathias V, Craddock, Nick, Craig, Ian W, Czamara, Darina, De Geus, Eco J, Degenhardt, Franziska, Farmer, Anne E, Fava, Maurizio, Frank, Josef, Gainer, Vivian S, Gallagher, Patience J, Karbalai, Nazanin, Gordon, Scott D, Goryachev, Sergey, Gross, Magdalena, Guipponi, Michel, Henders, Anjali K, Herms, Stefan, Hickie, Ian B, Hoefels, Susanne, Hoogendijk, Witte, Hottenga, Jouke Jan, Iosifescu, Dan V, Ising, Marcus, Jones, Ian, Jones, Lisa, Jung-Ying, Tzeng, Knowles, James A, Kohane, Isaac S, Kohli, Martin A, Korszun, Ania, Landen, Mikael

Publikováno v: Arloth, J, Bogdan, R, Weber, P, Frishman, G, Menke, A, Wagner, K V, Balsevich, G, Schmidt, M V, Karbalai, N, Czamara, D, Altmann, A, Trümbach, D, Wurst, W, Mehta, D, Uhr, M, Klengel, T, Erhardt, A, Carey, C E, Drabant Conley, E, Boomsma, D I, Penninx, B W J H, de Geus, E J C, Hottenga, J J, Middeldorp, C M, Willemsen, G, Smit, J H, Ruepp, A, Müller-Myhsok, B, Hariri, A & Binder, E B 2015, ' Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders ', Neuron, vol. 86, pp. 1189-1202 . https://doi.org/10.1016/j.neuron.2015.05.034
Neuron 86, 1189-1202 (2015)
Neuron, 86, 1189-1202. Cell Press
Neuron
Neuron 86(5), 1189-1202 (2015). doi:10.1016/j.neuron.2015.05.034
NEURON

Summary Depression risk is exacerbated by genetic factors and stress exposure; however, the biological mechanisms through which these factors interact to confer depression risk are poorly understood. One putative biological mechanism implicates varia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f8e3dd82fe25b350acb65eab97194b
https://eprints.worc.ac.uk/5045/1/1-s2.0-S0896627315004730-main.pdf

A mega-analysis of genome-wide association studies for major depressive disorder.

Autor: Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PA, Martin NG, McGuffin P, Muglia P, Noethen MM, Penninx BP, Pergadia ML, Potash JB, Rietschel M, Lin D, Müller-Myhsok B, Shi J, Steinberg S, Grabe HJ, Lichtenstein P, Magnusson P, Perlis RH, Preisig M, Smoller JW, Stefansson K, Uher R, Kutalik Z, Tansey KE, Teumer A, Viktorin A, Barnes MR, Bettecken T, Binder EB, Breuer R, Castro VM, Churchill SE, Coryell WH, Craddock N, Craig IW, Czamara D, De Geus EJ, Degenhardt F, Farmer AE, Fava M, Frank J, Gainer VS, Gallagher PJ, Gordon SD, Goryachev S, Gross M, Guipponi M, Henders AK, Herms S, Hickie IB, Hoefels S, Hoogendijk W, Hottenga JJ, Iosifescu DV, Ising M, Jones I, Jones L, Jung-Ying T, Knowles JA, Kohane IS, Kohli MA, Korszun A, Landen M, Lawson WB, Lewis G, Macintyre D, Maier W, Mattheisen M, McGrath PJ, McIntosh A, McLean A, Middeldorp CM, Middleton L, Montgomery GM, Murphy SN, Nauck M, Nolen WA, Nyholt DR, O'Donovan M, Oskarsson H, Pedersen N, Scheftner WA, Schulz A, Schulze TG, Shyn SI, Sigurdsson E, Slager SL, Smit JH, Stefansson H, Steffens M, Thorgeirsson T, Tozzi F, Treutlein J, Uhr M, van den Oord EJ, Van Grootheest G, Völzke H, Weilburg JB, Willemsen G, Zitman FG, Neale B, Daly M, Levinson DF, Sullivan PF

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2013 Apr; Vol. 18 (4), pp. 497-511. Date of Electronic Publication: 2012 Apr 03.