In vivo evaluation of a novel ¹⁸F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain.

Autor: Yan, Xuefeng, Siméon, Fabrice G., Liow, Jeih-San, Morse, Cheryl L., Montero Santamaria, Jose A., Jenkins, Madeline, Manly, Lester S., Van Buskirk, Maia, Zoghbi, Sami S., Pike, Victor W., Innis, Robert B., Zanotti-Fregonara, Paolo

Publikováno v: European Journal of Nuclear Medicine & Molecular Imaging; Aug2023, Vol. 50 Issue 10, p2962-2970, 9p, 1 Color Photograph, 1 Diagram, 1 Chart, 4 Graphs

Whole-body PET imaging in humans shows that ¹¹C-PS13 is selective for cyclooxygenase-1 and can measure the in vivo potency of nonsteroidal anti-inflammatory drugs.

Autor: Kim, Min-Jeong, Anaya, Fernanda Juarez, Manly, Lester S., Lee, Jae-Hoon, Hong, Jinsoo, Shrestha, Stal, Telu, Sanjay, Henry, Katharine, Montero Santamaria, Jose A., Liow, Jeih-San, Zanotti-Fregonara, Paolo, Umesha Shetty, H., Zoghbi, Sami S., Pike, Victor W., Innis, Robert B.

Publikováno v: Journal of Nuclear Medicine; Oct2022, Vol. 63 Issue 10, p1-44, 44p

In vivo evaluation of six analogs of ¹¹C-ER176 as candidate ¹⁸F-labeled radioligands for translocator protein 18 kDa (TSPO).

Autor: Jae-Hoon Lee, Siméon, Fabrice G., Liow, Jeih-San, Morse, Cheryl L., Gladding, Robert L., Montero Santamaria, Jose A., Henter, Ioline D., Zoghbi, Sami S., Pike, Victor W., Innis, Robert B.

Publikováno v: Journal of Nuclear Medicine; Oct2022, Vol. 63 Issue 10, Following p1-28, 37p

First-in-human evaluation of ¹⁸F-PF-06445974, a PET radioligand that preferentially labels phosphodiesterase-4B.

Autor: Wakabayashi, Yuichi, Stenkrona, Per, Arakawa, Ryosuke, Xuefeng Yan, Van Buskirk, Maia G., Jenkins, Madeline D., Montero Santamaria, Jose A., Maresca, Kevin P., Takano, Akihiro, Liow, Jeih-San, Chappie, Thomas A., Varrone, Andrea, Nag, Sangram, Lei Zhang, Hughes, Zoë A, Schmidt, Christopher J., Doran, Shawn D., Mannes, Andrew, Zanotti-Fregonara, Paolo, Ooms, Maarten

Publikováno v: Journal of Nuclear Medicine; Sep2022, Vol. 63 Issue 9, Following p1-25, 38p

Whole-body PET imaging in humans shows that ¹¹C-PS13 is selective for cyclooxygenase-1 and can measure the in vivo potency of nonsteroidal anti-inflammatory drugs.

Autor: Min-Jeong Kim, Anaya, Fernanda Juarez, Manly, Lester S., Jae-Hoon Lee, Jinsoo Hong, Shrestha, Stal, Telu, Sanjay, Henry, Katharine, Montero Santamaria, Jose A., Jeih-San Liow, Zanotti-Fregonara, Paolo, Shetty, H. Umesha, Zoghbi, Sami S., Pike, Victor W., Innis, Robert B.

Publikováno v: Journal of Nuclear Medicine; jul2022, Vol. 63 Issue 7, p1-26, 32p