Zobrazeno 1 - 10 of 35 pro vyhledávání: '"Montemiglio LC"'
1
Investigating the structural plasticity of a cytochrome P450: 3D structure of EryK and binding to its physiological substrate and inhibitors
Autor: Montemiglio, LC [ 1 ], Vallone, B [ 1 ], Gianni, S [ 2 ], Savino, C
Publikováno v: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine, pp. 120–120, Torino, ITALY, JUN 25-30, 2011
info:cnr-pdr/source/autori:Montemiglio, LC [ 1 ] ; Vallone, B [ 1 ] ; Gianni, S [ 2 ] ; Savino, C/congresso_nome:36th FEBS Congress of the Biochemistry for Tomorrows Medicine/congresso_luogo:Torino, ITALY/congresso_data:JUN 25-30, 2011/anno:2011/pagina_da:120/pagina_a:120/intervallo_pagine:120–120
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6f8749df35c30579a6bc3489cf8a1228
http://hdl.handle.net/11573/468966
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2
Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate
Autor: Savino C, Montemiglio LC, Sciara G, Miele AE, Kendrew SG, Jemth P, Gianni S, Vallone B.
Publikováno v: The Journal of biological chemistry
284 (2009): 29170–29179. doi:10.1074/jbc.M109.003590
info:cnr-pdr/source/autori:Savino C; Montemiglio LC; Sciara G; Miele AE; Kendrew SG; Jemth P; Gianni S; Vallone B./titolo:Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate/doi:10.1074%2Fjbc.M109.003590/rivista:The Journal of biological chemistry (Print)/anno:2009/pagina_da:29170/pagina_a:29179/intervallo_pagine:29170–29179/volume:284
Cytochrome P450s are heme-containing proteins that catalyze the oxidative metabolism of many physiological endogenous compounds. Because of their unique oxygen chemistry and their key role in drug and xenobiotic metabolism, particular attention has b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::38a29ac4b78264b9b57e269e37b44a1f
https://publications.cnr.it/doc/11751
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3
Akademický článek
Binding of steroid substrates reveals the key to the productive transition of the cytochrome P450 OleP.
Autor: Costanzo A; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, P. le Aldo Moro, 5, 00185 Rome, Italy; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Fata F; Institute of Molecular Biology and Pathology c/o Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, National Research Council, P.le Aldo Moro, 5, 00185 Rome, Italy., Freda I; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, P. le Aldo Moro, 5, 00185 Rome, Italy., De Sciscio ML; Department of Chemistry, University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Gugole E; Institute of Molecular Biology and Pathology c/o Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, National Research Council, P.le Aldo Moro, 5, 00185 Rome, Italy., Bulfaro G; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, P. le Aldo Moro, 5, 00185 Rome, Italy; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Di Renzo M; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, P. le Aldo Moro, 5, 00185 Rome, Italy., Barbizzi L; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, P. le Aldo Moro, 5, 00185 Rome, Italy., Exertier C; Institute of Molecular Biology and Pathology c/o Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, National Research Council, P.le Aldo Moro, 5, 00185 Rome, Italy., Parisi G; Department of Basic and Applied Sciences for Engineering (SBAI), Sapienza, University of Rome, Via Antonio Scarpa, 16, 00161 Rome, Italy., D'Abramo M; Department of Chemistry, University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Vallone B; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, P. le Aldo Moro, 5, 00185 Rome, Italy; Institute of Molecular Biology and Pathology c/o Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, National Research Council, P.le Aldo Moro, 5, 00185 Rome, Italy. Electronic address: beatrice.vallone@uniroma1.it., Savino C; Institute of Molecular Biology and Pathology c/o Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, National Research Council, P.le Aldo Moro, 5, 00185 Rome, Italy. Electronic address: carmelinda.savino@cnr.it., Montemiglio LC; Institute of Molecular Biology and Pathology c/o Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, National Research Council, P.le Aldo Moro, 5, 00185 Rome, Italy. Electronic address: lindaceleste.montemiglio@cnr.it.
Publikováno v: Structure (London, England : 1993) [Structure] 2024 Sep 05; Vol. 32 (9), pp. 1465-1476.e3. Date of Electronic Publication: 2024 Jul 05.
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4
Akademický článek
Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1.
Autor: Spizzichino S; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Di Fonzo F; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Marabelli C; Department of Molecular Medicine, University of Pavia, Via Forlanini 3, 27100 Pavia, Italy., Tramonti A; Institute of Molecular Biology and Pathology, National Research Council, P.le A. Moro 5, 00185 Rome, Italy., Chaves-Sanjuan A; Department of Biosciences, University of Milan, Via Celoria 26, 20133 Milano, Italy; Fondazione Romeo e Enrica Invernizzi and NOLIMITS, University of Milan, Via Celoria 26, 20133 Milan, Italy., Parroni A; Institute of Molecular Biology and Pathology, National Research Council, P.le A. Moro 5, 00185 Rome, Italy., Boumis G; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Liberati FR; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Paone A; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy; Department of Biochemical Sciences, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, P.le A. Moro 5, 00185 Rome, Italy., Montemiglio LC; Institute of Molecular Biology and Pathology, National Research Council, P.le A. Moro 5, 00185 Rome, Italy., Ardini M; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy., Jakobi AJ; Department of Bionanoscience, Kavli Institute of Nanoscience Deft, Delft University of Technology, Van der Maasweg, 92629 HZ Delft, the Netherlands., Bharadwaj A; Department of Bionanoscience, Kavli Institute of Nanoscience Deft, Delft University of Technology, Van der Maasweg, 92629 HZ Delft, the Netherlands., Swuec P; CryoElectron Microscopy Facility, Human Technopole, Viale Rita Levi-Montalcini 1, 20157 Milan, Italy., Tartaglia GG; Centre for Human Technologies (CHT), Istituto Italiano di Tecnologia (IIT), Via Enrico Melen, 83, 16152 Genova, Italy; Department of Biology 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy., Paiardini A; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Contestabile R; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Mai A; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Rotili D; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Fiorentino F; Department of Drug Chemistry and Technologies, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Macone A; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Giorgi A; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Tria G; CNR Institute of Crystallography - URT Caserta c/o Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche (DiSTABiF), Università degli Studi della Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy., Rinaldo S; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy., Bolognesi M; Department of Biosciences, University of Milan, Via Celoria 26, 20133 Milano, Italy; Fondazione Romeo e Enrica Invernizzi and NOLIMITS, University of Milan, Via Celoria 26, 20133 Milan, Italy., Giardina G; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy. Electronic address: giorgio.giardina@uniroma1.it., Cutruzzolà F; Department of Biochemical Sciences, Sapienza University of Rome, P. le Aldo Moro 5, 00185 Rome, Italy; Department of Biochemical Sciences, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, P.le A. Moro 5, 00185 Rome, Italy. Electronic address: francesca.cutruzzola@uniroma1.it.
Publikováno v: Molecular cell [Mol Cell] 2024 Jul 25; Vol. 84 (14), pp. 2682-2697.e6. Date of Electronic Publication: 2024 Jul 11.
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5
Akademický článek
Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Autor: Freda I; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza, University of Rome, Rome 00185, Italy., Exertier C; Institute of Molecular Biology and Pathology, National Research Council, Rome 00185, Italy., Barile A; Institute of Molecular Biology and Pathology, National Research Council, Rome 00185, Italy., Chaves-Sanjuan A; Department of Biosciences, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi and NOLIMITS, University of Milano, Milano 20133, Italy., Vega MV; School of Biochemistry, University of Bristol, University Walk, BS8 1TD Bristol, UK., Isupov MN; Geoffrey Pope Building, University of Exeter, Stocker Road, Exeter EX4 4QD, UK., Harmer NJ; Living Systems Institute, University of Exeter, Stocker Road, Exeter EX4 4QD, UK., Gugole E; Institute of Molecular Biology and Pathology, National Research Council, Rome 00185, Italy., Swuec P; Cryo-Electron Microscopy Core Facility, Human Technopole, Milano 20157, Italy., Bolognesi M; Department of Biosciences, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi and NOLIMITS, University of Milano, Milano 20133, Italy., Scipioni A; Department of Chemistry, Sapienza, University of Rome, Rome 00185, Italy., Savino C; Institute of Molecular Biology and Pathology, National Research Council, Rome 00185, Italy., Di Salvo ML; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza, University of Rome, Rome 00185, Italy., Contestabile R; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza, University of Rome, Rome 00185, Italy.; Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza, University of Rome, Rome 00185, Italy., Vallone B; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza, University of Rome, Rome 00185, Italy.; Institute of Molecular Biology and Pathology, National Research Council, Rome 00185, Italy., Tramonti A; Institute of Molecular Biology and Pathology, National Research Council, Rome 00185, Italy., Montemiglio LC; Institute of Molecular Biology and Pathology, National Research Council, Rome 00185, Italy.
Publikováno v: Nucleic acids research [Nucleic Acids Res] 2023 Aug 25; Vol. 51 (15), pp. 8237-8254.
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6
Akademický článek
Effect of Salts on the Conformational Dynamics of the Cytochrome P450 OleP.
Autor: De Sciscio ML; Department of Chemistry, University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Nardi AN; Department of Chemistry, University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Parisi G; Center for Life Nano & Neuro-Science, Fondazione Istituto Italiano di Tecnologia, IIT, 00185 Rome, Italy., Bulfaro G; Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy.; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Costanzo A; Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy.; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy.; Institute of Molecular Biology and Pathology, CNR c/o Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Gugole E; Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Exertier C; Institute of Molecular Biology and Pathology, CNR c/o Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Freda I; Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Savino C; Institute of Molecular Biology and Pathology, CNR c/o Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Vallone B; Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Montemiglio LC; Institute of Molecular Biology and Pathology, CNR c/o Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., D'Abramo M; Department of Chemistry, University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy.
Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2023 Jan 13; Vol. 28 (2). Date of Electronic Publication: 2023 Jan 13.
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7
Akademický článek
Probing the Role of Murine Neuroglobin CDloop-D-Helix Unit in CO Ligand Binding and Structural Dynamics.
Autor: Exertier C; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza, Università di Roma, Piazzale A. Moro 5, I-00185 Rome, Italy., Sebastiani F; Dipartimento di Chimica ″Ugo Schiff″, Università di Firenze, Via della Lastruccia 3-13, I-50019 Sesto Fiorentino, Italy., Freda I; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza, Università di Roma, Piazzale A. Moro 5, I-00185 Rome, Italy., Gugole E; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza, Università di Roma, Piazzale A. Moro 5, I-00185 Rome, Italy., Cerutti G; Zuckerman Mind Brain Behavior Institute, Columbia University, 3227 Broadway, New York, New York 10027, United States., Parisi G; Center for Life Nanoscience, Istituto Italiano di Tecnologia, Viale Regina Elena, 291, I-00161 Rome, Italy., Montemiglio LC; Institute of Molecular Biology and Pathology, National Research Council, Piazzale A. Moro 5, 00185 Rome, Italy., Becucci M; Dipartimento di Chimica ″Ugo Schiff″, Università di Firenze, Via della Lastruccia 3-13, I-50019 Sesto Fiorentino, Italy., Viappiani C; Department of Mathematical, Physical and Computer Sciences, University of Parma, Parco Area delle Scienze, 7/A, I-43124 Parma, Italy., Bruno S; Department of Food and Drugs, University of Parma, Parco Area delle Scienze 27/A, I-43124 Parma, Italy., Savino C; Institute of Molecular Biology and Pathology, National Research Council, Piazzale A. Moro 5, 00185 Rome, Italy., Zamparelli C; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza, Università di Roma, Piazzale A. Moro 5, I-00185 Rome, Italy., Anselmi M; Theoretical Physics and Center for Biophysics, Saarland University, Campus E2 6, 66123 Saarbrücken, Germany., Abbruzzetti S; Department of Mathematical, Physical and Computer Sciences, University of Parma, Parco Area delle Scienze, 7/A, I-43124 Parma, Italy., Smulevich G; Dipartimento di Chimica ″Ugo Schiff″, Università di Firenze, Via della Lastruccia 3-13, I-50019 Sesto Fiorentino, Italy., Vallone B; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza, Università di Roma, Piazzale A. Moro 5, I-00185 Rome, Italy.
Publikováno v: ACS chemical biology [ACS Chem Biol] 2022 Aug 19; Vol. 17 (8), pp. 2099-2108. Date of Electronic Publication: 2022 Jul 07.
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8
Akademický článek
Neuroglobin, clues to function and mechanism.
Autor: Exertier C; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza, Università di Roma, P.le A. Moro 5, 00185, Rome, Italy., Montemiglio LC; Institute of Molecular Biology and Pathology, National Research Council, P.le A. Moro 5, 00185, Rome, Italy., Freda I; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza, Università di Roma, P.le A. Moro 5, 00185, Rome, Italy., Gugole E; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza, Università di Roma, P.le A. Moro 5, 00185, Rome, Italy., Parisi G; Center for Life Nanoscience, Istituto Italiano di Tecnologia, 00161, Rome, Italy., Savino C; Institute of Molecular Biology and Pathology, National Research Council, P.le A. Moro 5, 00185, Rome, Italy. Electronic address: carmelinda.savino@cnr.it., Vallone B; Dipartimento di Scienze Biochimiche 'A. Rossi Fanelli', Sapienza, Università di Roma, P.le A. Moro 5, 00185, Rome, Italy. Electronic address: beatrice.vallone@uniroma1.it.
Publikováno v: Molecular aspects of medicine [Mol Aspects Med] 2022 Apr; Vol. 84, pp. 101055. Date of Electronic Publication: 2021 Dec 06.
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9
Akademický článek
Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics.
Autor: Montemiglio LC; Institute of Molecular Biology and Pathology, CNR c/o Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Gugole E; Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Freda I; Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Exertier C; Institute of Molecular Biology and Pathology, CNR c/o Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., D'Auria L; Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Chen CG; Department of Chemistry, University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Nardi AN; Department of Chemistry, University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Cerutti G; Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Parisi G; Center for Life Nano & Neuro-Science, Fondazione Istituto Italiano di Tecnologia, IIT, 00185 Rome, Italy., D'Abramo M; Department of Chemistry, University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Savino C; Institute of Molecular Biology and Pathology, CNR c/o Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy., Vallone B; Department of Biochemical Sciences 'A. Rossi Fanelli', University of Rome, Sapienza, P.le A. Moro 5, 00185 Rome, Italy.
Publikováno v: Biomolecules [Biomolecules] 2021 Dec 31; Vol. 12 (1). Date of Electronic Publication: 2021 Dec 31.
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10
Akademický článek
The Nuts and Bolts of SARS-CoV-2 Spike Receptor-Binding Domain Heterologous Expression.
Autor: Maffei M; Evvivax Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Montemiglio LC; Institute of Molecular Biology and Pathology (IBPM), National Research Council, c/o Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, P. le Aldo Moro, 5, 00185 Rome, Italy., Vitagliano G; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Fedele L; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Sellathurai S; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Bucci F; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Compagnone M; Neomatrix Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Chiarini V; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Exertier C; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, P. le Aldo Moro, 5, 00185 Rome, Italy., Muzi A; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Roscilli G; Evvivax Biotech, Via di Castel Romano 100, 00128 Rome, Italy.; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy., Vallone B; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza, University of Rome, P. le Aldo Moro, 5, 00185 Rome, Italy., Marra E; Evvivax Biotech, Via di Castel Romano 100, 00128 Rome, Italy.; Takis Biotech, Via di Castel Romano 100, 00128 Rome, Italy.
Publikováno v: Biomolecules [Biomolecules] 2021 Dec 02; Vol. 11 (12). Date of Electronic Publication: 2021 Dec 02.
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