Incremental value of serum neurofilament light chain and glial fibrillary acidic protein as blood-based biomarkers for predicting functional outcome in severe acute ischemic stroke.

Autor: Vollmuth C; University Hospital Würzburg, Department of Neurology, Würzburg, Germany., Fiessler C; University of Würzburg, Institute for Clinical Epidemiology and Biometry, Würzburg, Germany., Montellano FA; University Hospital Würzburg, Department of Neurology, Würzburg, Germany.; University of Würzburg, Institute for Clinical Epidemiology and Biometry, Würzburg, Germany., Kollikowski AM; University Hospital Würzburg, Department of Neuroradiology, Würzburg, Germany., Essig F; University Hospital Würzburg, Department of Neurology, Würzburg, Germany., Oeckl P; University Hospital Ulm, Department of Neurology, Ulm, Germany.; German Center for Neurodegenerative Diseases e.V. (DZNE) Ulm, Ulm, Germany., Barba L; Martin-Luther-University of Halle-Wittenberg, Department of Neurology, Halle (Saale), Germany., Steinacker P; Martin-Luther-University of Halle-Wittenberg, Department of Neurology, Halle (Saale), Germany., Schulz C; University Hospital Würzburg, Department of Neurology, Würzburg, Germany., Ungethüm K; University of Würzburg, Institute for Clinical Epidemiology and Biometry, Würzburg, Germany., Wolf J; University Hospital Würzburg, Department of Neurology, Würzburg, Germany., Pham M; University Hospital Würzburg, Department of Neuroradiology, Würzburg, Germany., Schuhmann MK; University Hospital Würzburg, Department of Neurology, Würzburg, Germany., Heuschmann PU; University of Würzburg, Institute for Clinical Epidemiology and Biometry, Würzburg, Germany.; Institute for Medical Data Science, University Hospital Würzburg, Würzburg, Germany.; Clinical Trial Centre, University Hospital Würzburg, Würzburg, Germany., Haeusler KG; University Hospital Würzburg, Department of Neurology, Würzburg, Germany., Stoll G; University Hospital Würzburg, Department of Neurology, Würzburg, Germany., Otto M; Martin-Luther-University of Halle-Wittenberg, Department of Neurology, Halle (Saale), Germany., Neugebauer H; University Hospital Würzburg, Department of Neurology, Würzburg, Germany.

Publikováno v: European stroke journal [Eur Stroke J] 2024 Sep; Vol. 9 (3), pp. 751-762. Date of Electronic Publication: 2024 Feb 24.

Biomarkers to improve functional outcome prediction after ischemic stroke: Results from the SICFAIL, STRAWINSKI, and PREDICT studies.

Autor: Montellano FA; Institute of Clinical Epidemiology and Biometry, Julius-Maximilians-Universität (JMU) Würzburg, Würzburg, Germany.; Department of Neurology, University Hospital Würzburg, Würzburg, Germany.; Interdisciplinary Center for Clinical Research, University Hospital Würzburg, Würzburg, Germany., Rücker V; Institute of Clinical Epidemiology and Biometry, Julius-Maximilians-Universität (JMU) Würzburg, Würzburg, Germany., Ungethüm K; Institute of Clinical Epidemiology and Biometry, Julius-Maximilians-Universität (JMU) Würzburg, Würzburg, Germany.; Institute of Medical Data Science, University Hospital Würzburg, Würzburg, Germany., Penalba A; Neurovascular Research Laboratory, Vall d'Hebron Institute of Research, Universitat Autònoma de Barcelona, Barcelona, Spain., Hotter B; Department of Neurology and Experimental Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Center for Stroke Research Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany.; NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany., Giralt M; Department of Biochemistry, Vall d'Hebron University Hospital, Barcelona, Spain., Wiedmann S; Institute of Clinical Epidemiology and Biometry, Julius-Maximilians-Universität (JMU) Würzburg, Würzburg, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany., Mackenrodt D; Institute of Clinical Epidemiology and Biometry, Julius-Maximilians-Universität (JMU) Würzburg, Würzburg, Germany.; Department of Neurology, University Hospital Würzburg, Würzburg, Germany., Morbach C; Department Clinical Research & Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.; Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany., Frantz S; Department Clinical Research & Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany., Störk S; Department Clinical Research & Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.; Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany., Whiteley WN; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., Kleinschnitz C; Department of Neurology and Center for Translational Neuroscience and Behavioural Science (C-TNBS), University Hospital Essen, Essen, Germany., Meisel A; Department of Neurology and Experimental Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Center for Stroke Research Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany.; NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany., Montaner J; Neurovascular Research Laboratory, Vall d'Hebron Institute of Research, Universitat Autònoma de Barcelona, Barcelona, Spain.; Stroke Research Program, Instituto de Biomedicina de Sevilla/Hospital Universitario Virgen del Rocío/Consejo Superior de Investigaciones Científicas/University of Seville, Seville, Spain.; Department of Neurology, Hospital Universitario Virgen Macarena, Seville, Spain., Haeusler KG; Department of Neurology, University Hospital Würzburg, Würzburg, Germany., Heuschmann PU; Institute of Clinical Epidemiology and Biometry, Julius-Maximilians-Universität (JMU) Würzburg, Würzburg, Germany.; Institute of Medical Data Science, University Hospital Würzburg, Würzburg, Germany.; Clinical Trial Center Würzburg, University Hospital Würzburg, Würzburg, Germany.

Publikováno v: European stroke journal [Eur Stroke J] 2024 May 06, pp. 23969873241250272. Date of Electronic Publication: 2024 May 06.

Persistent symptoms and risk factors predicting prolonged time to symptom-free after SARS‑CoV‑2 infection: an analysis of the baseline examination of the German COVIDOM/NAPKON-POP cohort.

Autor: Shi Y; Institute for Medical Information Processing, Biometry and Epidemiology (IBE), Faculty of Medicine, Ludwig-Maximilians-Universität München (LMU Munich), Marchioninistr. 15, 81377, Munich, Germany.; Pettenkofer School of Public Health, Munich, Germany., Strobl R; Institute for Medical Information Processing, Biometry and Epidemiology (IBE), Faculty of Medicine, Ludwig-Maximilians-Universität München (LMU Munich), Marchioninistr. 15, 81377, Munich, Germany.; German Center for Vertigo and Balance Disorders, University Hospital, Ludwig-Maximilians-Universität München (LMU Munich), Munich, Germany., Apfelbacher C; Institute of Social Medicine and Health Systems Research, Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany., Bahmer T; Internal Medicine Department I, University Hospital Schleswig-Holstein Campus Kiel (UKSH Kiel), Kiel, Germany., Geisler R; Department II of Internal Medicine, Hematology/Oncology, Goethe University, Frankfurt, Frankfurt Am Main, Germany., Heuschmann P; Institute for Clinical Epidemiology and Biometry, Julius-Maximilians-University, Würzburg, Würzburg, Germany.; Clinical Trial Center, University Hospital Würzburg, Würzburg, Germany., Horn A; Institute for Clinical Epidemiology and Biometry, Julius-Maximilians-University, Würzburg, Würzburg, Germany., Hoven H; Institute for Occupational and Maritime Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Keil T; Institute for Clinical Epidemiology and Biometry, Julius-Maximilians-University, Würzburg, Würzburg, Germany.; Institute of Social Medicine, Epidemiology and Health Economics, Charité-Universitätsmedizin Berlin, Berlin, Germany.; State Institute of Health I, Bavarian Health and Food Safety Authority, Erlangen, Germany., Krawczak M; Institute of Medical Informatics and Statistics, Kiel University, University Medical Center Schleswig-Holstein, Kiel, Germany., Krist L; Institute of Social Medicine, Epidemiology and Health Economics, Charité-Universitätsmedizin Berlin, Berlin, Germany., Lemhöfer C; Institute of Physical and Rehabilitation Medicine, University Hospital Jena, Jena, Germany., Lieb W; Institute of Epidemiology, Kiel University, University Medical Center Schleswig-Holstein, Kiel, Germany., Lorenz-Depiereux B; Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Center Munich, Munich, Germany., Mikolajczyk R; Institute for Medical Epidemiology, Biometrics, and Informatics, Interdisciplinary Center for Health Sciences, Medical Faculty of the Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.; German Centre for Mental Health, Site Jena-Magdeburg-Halle, Halle, Germany., Montellano FA; Institute for Clinical Epidemiology and Biometry, Julius-Maximilians-University, Würzburg, Würzburg, Germany.; Department of Neurology, University Hospital Würzburg, Würzburg, Germany., Reese JP; Institute for Clinical Epidemiology and Biometry, Julius-Maximilians-University, Würzburg, Würzburg, Germany., Schreiber S; Internal Medicine Department I, University Hospital Schleswig-Holstein Campus Kiel (UKSH Kiel), Kiel, Germany., Skoetz N; Evidence-Based Medicine, Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Störk S; Department of Clinical Research and Epidemiology, Comprehensive Heart Failure Center and Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany., Vehreschild JJ; Department II of Internal Medicine, Hematology/Oncology, Goethe University, Frankfurt, Frankfurt Am Main, Germany.; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; German Centre for Infection Research (DZIF), Partner Site Bonn‑Cologne, Cologne, Germany., Witzenrath M; Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Center for Lung Research (DZL), Giessen, Germany., Grill E; Institute for Medical Information Processing, Biometry and Epidemiology (IBE), Faculty of Medicine, Ludwig-Maximilians-Universität München (LMU Munich), Marchioninistr. 15, 81377, Munich, Germany. Eva.Grill@med.uni-muenchen.de.; German Center for Vertigo and Balance Disorders, University Hospital, Ludwig-Maximilians-Universität München (LMU Munich), Munich, Germany. Eva.Grill@med.uni-muenchen.de.

Publikováno v: Infection [Infection] 2023 Dec; Vol. 51 (6), pp. 1679-1694. Date of Electronic Publication: 2023 May 25.

Persisting chemosensory dysfunction in COVID-19 - a cross-sectional population-based survey.

Autor: Winkelmann S; Department of Otorhinolaryngology, Head and Neck Surgery, Kiel University, University Medical Centre Schleswig-Holstein, Kiel, Germany., Korth A; Department of Otorhinolaryngology, Head and Neck Surgery, Kiel University, University Medical Centre Schleswig-Holstein, Kiel, Germany., Voss B; Department of Otorhinolaryngology, Head and Neck Surgery, Kiel University, University Medical Centre Schleswig-Holstein, Kiel, Germany., Nasr MA; Department of Otorhinolaryngology, Head and Neck Surgery, Kiel University, University Medical Centre Schleswig-Holstein, Kiel, Germany., Behrend N; Department of Otorhinolaryngology, Head and Neck Surgery, Kiel University, University Medical Centre Schleswig-Holstein, Kiel, Germany., Pudszuhn A; Department of Otorhinolaryngology, Head and Neck Surgery, Charity-Universitatsmedizin Berlin, Corporate Member of Freie Universitat Berlin, Humboldt-Universitat zu Berlin and Berlin Institute of Health, Campus Benjamin Franklin, Berlin, Germany., Hofmann VM; Department of Otorhinolaryngology, Head and Neck Surgery, Charity-Universitatsmedizin Berlin, Corporate Member of Freie Universitat Berlin, Humboldt-Universitat zu Berlin and Berlin Institute of Health, Campus Benjamin Franklin, Berlin, Germany., Schendzielorz P; Department of Oto-Rhino-Laryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery and the Comprehensive Hearing Center, University of Wurzburg, Wurzburg, Germany., Maetzler C; Neurology Department, University Medical Center Schleswig-Holstein Campus Kiel, Kiel, Germany., Hermes A; Institute of Epidemiology, Kiel University, University Medical Center Schleswig-Holstein, Kiel, Germany., Borzikowsky C; Institute of Medical Informatics and Statistics, Kiel University, University Medical Centre Schleswig-Holstein, Kiel, Germany., Bahmer T; Division of Pneumology, Department of Medicine 1, Kiel University, University Medical Centre Schleswig-Holstein, Kiel, Germany., Lieb W; Institute of Epidemiology, Kiel University, University Medical Center Schleswig-Holstein, Kiel, Germany., Schreiber S; Internal Medicine Department I, University Medical Center Schleswig-Holstein Campus Kiel, Kiel, Germany., Stork S; Comprehensive Heart Failure Center and Dept. Internal Medicine I, University Hospital Wurzburg, Wurzburg, Germany., Montellano FA; Comprehensive Heart Failure Center and Dept. Internal Medicine I, University Hospital Wurzburg, Wurzburg, Germany; Institute of Clinical Epidemiology and Biometry, University of Wurzburg, Wurzburg, Germany; Department of Neurology, University Hospital Wurzburg, Wurzburg, Germany., Witzenrath M; Department of Infectious Diseases and Respiratory Medicine, Charity - Universitatsmedizin Berlin, Corporate Member of Freie Universitat Berlin and Humboldt-Universitat zu Berlin, Berlin, Germany., Keil T; Institute of Clinical Epidemiology and Biometry, University of Wurzburg, Wurzburg, Germany; Institute of Social Medicine, Epidemiology and Health Economics, Charity-Universitatsmedizin Berlin, Berlin, Germany., Krawczak M; Institute of Medical Informatics and Statistics, Kiel University, University Medical Centre Schleswig-Holstein, Kiel, Germany., Laudien M; Department of Otorhinolaryngology, Head and Neck Surgery, Kiel University, University Medical Centre Schleswig-Holstein, Kiel, Germany., On Behalf Of The Napkon Study Group NSG

Publikováno v: Rhinology [Rhinology] 2023 Feb 01; Vol. 61 (1), pp. 12-23.

Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries.

Autor: Mishra A; Bordeaux Population Health Research Center, University of Bordeaux, Inserm, UMR 1219, Bordeaux, France., Malik R; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Hachiya T; Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan., Jürgenson T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia., Namba S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan., Posner DC; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA., Kamanu FK; TIMI Study Group, Boston, MA, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Koido M; Division of Molecular Pathology, Institute of Medical Sciences, The University of Tokyo, Tokyo, Japan.; Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan., Le Grand Q; Bordeaux Population Health Research Center, University of Bordeaux, Inserm, UMR 1219, Bordeaux, France., Shi M; Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan., He Y; Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan., Georgakis MK; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Caro I; Bordeaux Population Health Research Center, University of Bordeaux, Inserm, UMR 1219, Bordeaux, France., Krebs K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Liaw YC; Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.; Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung, Taiwan., Vaura FC; Department of Internal Medicine, University of Turku, Turku, Finland.; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Turku, Finland., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Winsvold BS; Department of Research and Innovation, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.; Department of Neurology, Oslo University Hospital, Oslo, Norway., Srinivasasainagendra V; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA., Parodi L; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Bae HJ; Department of Neurology and Cerebrovascular Disease Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea., Chauhan G; Rajendra Institute of Medical Sciences, Ranchi, India., Chong MR; Thrombosis and Atherosclerosis Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Hamilton, Ontario, Canada.; Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada., Tomppo L; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Akinyemi R; Center for Genomic and Precision Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.; Neuroscience and Ageing Research Unit Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria., Roshchupkin GV; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Habib N; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Jee YH; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Thomassen JQ; Department of Clinical Biochemistry, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark., Abedi V; Department of Molecular and Functional Genomics, Weis Center for Research, Geisinger Health System, Danville, VA, USA.; Department of Public Health Sciences, College of Medicine, The Pennsylvania State University, State College, PA, USA., Cárcel-Márquez J; Stroke Pharmacogenomics and Genetics Laboratory, Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain.; Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain., Nygaard M; The Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark., Leonard HL; Center for Alzheimer's and Related Dementias, National Institutes of Health, Bethesda, MD, USA.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA., Yang C; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, USA., Yonova-Doing E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK., Knol MJ; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Lewis AJ; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Judy RL; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA., Ago T; Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Amouyel P; University of Lille, INSERM U1167, RID-AGE, LabEx DISTALZ, Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; CHU Lille, Public Health Department, Lille, France.; Institut Pasteur de Lille, Lille, France., Armstrong ND; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Bakker MK; UMC Utrecht Brain Center, Department of Neurology and Neurosurgery, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands., Bartz TM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Bordes C; Bordeaux Population Health Research Center, University of Bordeaux, Inserm, UMR 1219, Bordeaux, France., Børte S; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Research and Communication Unit for Musculoskeletal Health (FORMI), Department of Research and Innovation, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway., Cain A; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; MRC Population Health Research Unit, University of Oxford, Oxford, UK., Cruchaga C; Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, Saint Louis, MO, USA., Cole JW; VA Maryland Health Care System, Baltimore, MD, USA.; Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA., de Jager PL; Program in Medical and Population Genetics, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA.; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA., de Cid R; GenomesForLife-GCAT Lab Group, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Endres M; Klinik und Hochschulambulanz für Neurologie, Charité-Universitätsmedizin Berlin, Berlin, Germany.; Center for Stroke Research Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE), partner site Berlin, Berlin, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Berlin, Berlin, Germany., Ferreira LE; Post-Graduation Program on Health and Environment, Department of Medicine and Joinville Stroke Biobank, University of the Region of Joinville, Santa Catarina, Brazil., Geerlings MI; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Gasca NC; Department of Biostatistics, University of Washington, Seattle, WA, USA., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Hata J; Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., He J; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Heath AK; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Ho YL; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA., Havulinna AS; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine Finland, FIMM-HiLIFE, Helsinki, Finland., Hopewell JC; Clinical Trial Service and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Hyacinth HI; Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Inouye M; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Cambridge Baker Systems Genomics Initiative, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK., Jacob MA; Department of Neurology, Donders Center for Medical Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands., Jeon CE; Los Angeles County Department of Public Health, Los Angeles, CA, USA., Jern C; Institute of Biomedicine, Department of Laboratory Medicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden., Kamouchi M; Department of Health Care Administration and Management, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Keene KL; Department of Biology, Brody School of Medicine Center for Health Disparities, East Carolina University, Greenville, NC, USA., Kitazono T; Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Kittner SJ; Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Neurology and Geriatric Research and Education Clinical Center, VA Maryland Health Care System, Baltimore, MD, USA., Konuma T; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan., Kumar A; Rajendra Institute of Medical Sciences, Ranchi, India., Lacaze P; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Launer LJ; Intramural Research Program, National Institute on Aging, NIH, Baltimore, MD, USA., Lee KJ; Department of Neurology, Korea University Guro Hospital, Seoul, Republic of Korea., Lepik K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; University Center for Primary Care and Public Health, Lausanne, Switzerland., Li J; Department of Molecular and Functional Genomics, Weis Center for Research, Geisinger Health System, Danville, VA, USA., Li L; Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China., Manichaikul A; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Markus HS; Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Marston NA; TIMI Study Group, Boston, MA, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Meitinger T; Institute of Human Genetics, Technical University of Munich, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Mitchell BD; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA., Montellano FA; Institute of Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany.; Department of Neurology, University Hospital Würzburg, Würzburg, Germany., Morisaki T; Division of Molecular Pathology, Institute of Medical Sciences, The University of Tokyo, Tokyo, Japan., Mosley TH; The MIND Center, University of Mississippi Medical Center, Jackson, MS, USA., Nalls MA; Center for Alzheimer's and Related Dementias, National Institutes of Health, Bethesda, MD, USA.; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA., Nordestgaard BG; Department of Clinical Biochemistry, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., O'Donnell MJ; College of Medicine Nursing and Health Science, NUI Galway, Galway, Ireland., Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan.; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Japan.; Center for Infectious Disease Education and Research (CiDER), Osaka University, Suita, Japan., Onland-Moret NC; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Ovbiagele B; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Peters A; Institute of Epidemiology, Helmholtz Zentrum München,, German Research Center for Environmental Health, Neuherberg, Germany.; Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig Maximilian University Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Munich, Munich, Germany., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Rosand J; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA.; McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, USA., Sabatine MS; TIMI Study Group, Boston, MA, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Sacco RL; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.; Evelyn F. McKnight Brain Institute, Gainesville, FL, USA., Saleheen D; Division of Cardiology, Department of Medicine, Columbia University, New York, NY, USA., Sandset EC; Stroke Unit, Department of Neurology, Oslo University Hospital, Oslo, Norway.; Research and Development, The Norwegian Air Ambulance Foundation, Oslo, Norway., Salomaa V; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Sargurupremraj M; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, USA., Sasaki M; Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan., Satizabal CL; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, USA.; Framingham Heart Study, Framingham, MA, USA., Schmidt CO; University Medicine Greifswald, Institute for Community Medicine, SHIP/KEF, Greifswald, Germany., Shimizu A; 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Publikováno v: Nature [Nature] 2022 Dec; Vol. 612 (7938), pp. E7.