Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Monteiro OP"'
Autor:
João Paulo Costa
Publikováno v:
Revista Portuguesa de Filosofia. 76:1785-1788
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9477fd49ad6973414f5f202798aee7aa
https://doi.org/10.17990/rpf/2020_76_4_1785
https://doi.org/10.17990/rpf/2020_76_4_1785
Autor:
Amado, Raul
Publikováno v:
Theologica; Vol 41 No 1 (2006): Olhares sobre a família; 211-211
Theologica; v. 41 n. 1 (2006): Olhares sobre a família; 211-211
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Theologica; v. 41 n. 1 (2006): Olhares sobre a família; 211-211
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Theologica, v. 41 n. 1 (2006): Olhares sobre a família
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112a2924d36f558889a6aabfd9abb631
Autor:
Fedorov, O, Lingard, H, Wells, C, Monteiro, OP, Picaud, S, Keates, T, Yapp, C, Philpott, M, Martin, SJ, Felletar, I, Marsden, BD, Filippakopoulos, P, Müller, S, Knapp, S, Brennan, PE
Publikováno v:
Journal of Medicinal Chemistry
Bromodomains are gaining increasing interest as drug targets. Commercially sourced and de novo synthesized substituted [1,2,4]triazolo[4,3-a]phthalazines are potent inhibitors of both the BET bromodomains such as BRD4 as well as bromodomains outside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::743d9b400d3d2c4d25a3a009d369870a
https://doi.org/10.1021/jm401568s
https://doi.org/10.1021/jm401568s
Autor:
Moustakim M; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK.; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK., Christott T; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK., Monteiro OP; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK., Bennett J; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK., Giroud C; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK., Ward J; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK., Rogers CM; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK., Smith P; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK., Panagakou I; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK., Díaz-Sáez L; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK., Felce SL; Structural Genomics Consortium & Botnar Research Centre, University of Oxford, Windmill Road, Oxford, OX3 7LD, UK., Gamble V; Structural Genomics Consortium & Botnar Research Centre, University of Oxford, Windmill Road, Oxford, OX3 7LD, UK., Gileadi C; Structural Genomics Consortium & Botnar Research Centre, University of Oxford, Windmill Road, Oxford, OX3 7LD, UK., Halidi N; Structural Genomics Consortium & Botnar Research Centre, University of Oxford, Windmill Road, Oxford, OX3 7LD, UK., Heidenreich D; Institute for Pharmaceutical Chemistry and Buchmann Institute for Life Sciences, Johann Wolfgang Goethe-University, 60438, Frankfurt am Main, Germany., Chaikuad A; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK.; Institute for Pharmaceutical Chemistry and Buchmann Institute for Life Sciences, Johann Wolfgang Goethe-University, 60438, Frankfurt am Main, Germany., Knapp S; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK.; Institute for Pharmaceutical Chemistry and Buchmann Institute for Life Sciences, Johann Wolfgang Goethe-University, 60438, Frankfurt am Main, Germany., Huber KVM; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK., Farnie G; Structural Genomics Consortium & Botnar Research Centre, University of Oxford, Windmill Road, Oxford, OX3 7LD, UK., Heer J; UCB Pharma Ltd, Slough, SL1 3WE, UK., Manevski N; UCB Pharma Ltd, Slough, SL1 3WE, UK., Poda G; Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, ON, Canada.; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada., Al-Awar R; Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada., Dixon DJ; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK., Brennan PE; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK.; Alzheimer's Research (UK) Oxford Drug Discovery Institute, Nuffield Department of Medicine, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7FZ, UK., Fedorov O; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDMRB, Old Road Campus, Oxford, OX3 7DQ &, OX3 7FZ, UK.
Publikováno v:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2018 Dec 10; Vol. 57 (50), pp. 16302-16307. Date of Electronic Publication: 2018 Nov 16.
Autor:
Moustakim M; Structural Genomics Consortium, University of Oxford, ORCRB, Old Road Campus, Headington, Oxford, Oxfordshire OX3 7DQ, UK; Target Discovery Institute, University of Oxford, NDM Research Building, Old Road Campus, Headington, Oxford, Oxfordshire OX3 7FZ, UK; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, UK., Riedel K; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians University, Munich 81377, Germany., Schuller M; Structural Genomics Consortium, University of Oxford, ORCRB, Old Road Campus, Headington, Oxford, Oxfordshire OX3 7DQ, UK; Target Discovery Institute, University of Oxford, NDM Research Building, Old Road Campus, Headington, Oxford, Oxfordshire OX3 7FZ, UK., Gehring AP; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians University, Munich 81377, Germany., Monteiro OP; Structural Genomics Consortium, University of Oxford, ORCRB, Old Road Campus, Headington, Oxford, Oxfordshire OX3 7DQ, UK; Target Discovery Institute, University of Oxford, NDM Research Building, Old Road Campus, Headington, Oxford, Oxfordshire OX3 7FZ, UK., Martin SP; Charles River, Chesterford Research Park, CB10 1XL, UK., Fedorov O; Structural Genomics Consortium, University of Oxford, ORCRB, Old Road Campus, Headington, Oxford, Oxfordshire OX3 7DQ, UK; Target Discovery Institute, University of Oxford, NDM Research Building, Old Road Campus, Headington, Oxford, Oxfordshire OX3 7FZ, UK., Heer J; UCB Pharma Ltd, Slough SL1 3WE, UK., Dixon DJ; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, UK., Elkins JM; Structural Genomics Consortium, University of Oxford, ORCRB, Old Road Campus, Headington, Oxford, Oxfordshire OX3 7DQ, UK; Structural Genomics Consortium, Universidade Estadual de Campinas, Cidade Universitária Zeferino Vaz, Campinas, SP 13083-886, Brazil., Knapp S; Johann Wolfgang Goethe-University, Institute for PharmaceuticalChemistry and Buchmann Institute for Life Sciences, Frankfurt am Main 60438, Germany; German Cancer Centre (DKFZ) and DKTK site Frankfurt/Mainz, 60590, Germany., Bracher F; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians University, Munich 81377, Germany. Electronic address: franz.bracher@cup.uni-muenchen.de., Brennan PE; Structural Genomics Consortium, University of Oxford, ORCRB, Old Road Campus, Headington, Oxford, Oxfordshire OX3 7DQ, UK; Target Discovery Institute, University of Oxford, NDM Research Building, Old Road Campus, Headington, Oxford, Oxfordshire OX3 7FZ, UK. Electronic address: paul.brennan@sgc.ox.ac.uk.
Publikováno v:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2018 Jul 15; Vol. 26 (11), pp. 2965-2972. Date of Electronic Publication: 2018 Mar 12.
Autor:
Moustakim M; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ, UK.; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK., Clark PG; Department of Chemistry, Simon Fraser University, Burnaby, V5A 1S6, Canada., Trulli L; Dipartimento di Chimica, Università degli Studi di Roma 'La Sapienza', Piazzale Aldo Moro 5, 00185, Roma, Italy., Fuentes de Arriba AL; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK., Ehebauer MT; ARUK Oxford Drug Discovery Institute, University of Oxford, Oxford, OX3 7FZ, UK., Chaikuad A; Johann Wolfgang Goethe-University, Institute for Pharmaceutical Chemistry and Buchmann Institute for Life Sciences, 60438, Frankfurt am Main, Germany., Murphy EJ; ARUK Oxford Drug Discovery Institute, University of Oxford, Oxford, OX3 7FZ, UK., Mendez-Johnson J; Promega Corporation, 2800 Woods Hollow Road, Madison, WI, 153611, USA., Daniels D; Promega Corporation, 2800 Woods Hollow Road, Madison, WI, 153611, USA., Hou CD; Structural Genomics Consortium, MaRS South Tower, Suite 732, 101 College Street, Toronto, Ontario, M5G 1LZ, Canada., Lin YH; Structural Genomics Consortium, MaRS South Tower, Suite 732, 101 College Street, Toronto, Ontario, M5G 1LZ, Canada., Walker JR; Structural Genomics Consortium, MaRS South Tower, Suite 732, 101 College Street, Toronto, Ontario, M5G 1LZ, Canada., Hui R; Structural Genomics Consortium, MaRS South Tower, Suite 732, 101 College Street, Toronto, Ontario, M5G 1LZ, Canada., Yang H; Nuffield Department of Medicine and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, OX3 7FZ, UK., Dorrell L; Nuffield Department of Medicine and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, OX3 7FZ, UK., Rogers CM; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ, UK., Monteiro OP; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ, UK., Fedorov O; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ, UK., Huber KV; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ, UK., Knapp S; Johann Wolfgang Goethe-University, Institute for Pharmaceutical Chemistry and Buchmann Institute for Life Sciences, 60438, Frankfurt am Main, Germany., Heer J; UCB Pharma Ltd, Slough, SL1 3WE, UK., Dixon DJ; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK., Brennan PE; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ, UK.; ARUK Oxford Drug Discovery Institute, University of Oxford, Oxford, OX3 7FZ, UK.
Publikováno v:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2017 Jan 16; Vol. 56 (3), pp. 827-831. Date of Electronic Publication: 2016 Dec 14.
Autor:
Sutherell CL; Department of Chemistry, University of Cambridge , Lensfield Road, Cambridge, CB2 1EW, U.K.; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, CB2 0RE, U.K., Tallant C; The Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, U.K.; Target Discovery Institute, University of Oxford , NDM Research Building, Roosevelt Drive, Headington, Oxford OX3 7FZ, U.K., Monteiro OP; The Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, U.K.; Target Discovery Institute, University of Oxford , NDM Research Building, Roosevelt Drive, Headington, Oxford OX3 7FZ, U.K., Yapp C; The Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, U.K.; Target Discovery Institute, University of Oxford , NDM Research Building, Roosevelt Drive, Headington, Oxford OX3 7FZ, U.K., Fuchs JE; Department of Chemistry, University of Cambridge , Lensfield Road, Cambridge, CB2 1EW, U.K., Fedorov O; The Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, U.K.; Target Discovery Institute, University of Oxford , NDM Research Building, Roosevelt Drive, Headington, Oxford OX3 7FZ, U.K., Siejka P; The Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, U.K.; Target Discovery Institute, University of Oxford , NDM Research Building, Roosevelt Drive, Headington, Oxford OX3 7FZ, U.K., Müller S; The Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, U.K.; Target Discovery Institute, University of Oxford , NDM Research Building, Roosevelt Drive, Headington, Oxford OX3 7FZ, U.K., Knapp S; The Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, U.K.; Target Discovery Institute, University of Oxford , NDM Research Building, Roosevelt Drive, Headington, Oxford OX3 7FZ, U.K.; Department of Pharmaceutical Chemistry and Buchmann Institute for Life Sciences, Goethe University Frankfurt , 60438 Frankfurt am Main, Germany., Brenton JD; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, CB2 0RE, U.K., Brennan PE; The Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, U.K.; Target Discovery Institute, University of Oxford , NDM Research Building, Roosevelt Drive, Headington, Oxford OX3 7FZ, U.K., Ley SV; Department of Chemistry, University of Cambridge , Lensfield Road, Cambridge, CB2 1EW, U.K.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2016 May 26; Vol. 59 (10), pp. 5095-101. Date of Electronic Publication: 2016 May 11.
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Autor:
Clark PG; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK)., Vieira LC; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK)., Tallant C; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK)., Fedorov O; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK)., Singleton DC; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK)., Rogers CM; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK)., Monteiro OP; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK)., Bennett JM; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK)., Baronio R; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK)., Müller S; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK)., Daniels DL; Promega Corporation, 2800 Woods Hollow Road, Madison, W153611 (USA)., Méndez J; Promega Corporation, 2800 Woods Hollow Road, Madison, W153611 (USA)., Knapp S; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK)., Brennan PE; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK)., Dixon DJ; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK).
Publikováno v:
Angewandte Chemie (Weinheim an der Bergstrasse, Germany) [Angew Chem Weinheim Bergstr Ger] 2015 May 18; Vol. 127 (21), pp. 6315-6319. Date of Electronic Publication: 2015 Apr 13.
Autor:
Wang, Shuai1 (AUTHOR) wang.shuai@gene.com, Argikar, Upendra A.2 (AUTHOR), Cheruzel, Lionel1 (AUTHOR), Cho, Sungjoon1 (AUTHOR), Crouch, Rachel D.3 (AUTHOR), Dhaware, Deepika4 (AUTHOR), Heck, Carley J. S.5 (AUTHOR), Johnson, Kevin M.6 (AUTHOR), Kalgutkar, Amit S.7 (AUTHOR), King, Lloyd8 (AUTHOR), Liu, Joyce1 (AUTHOR), Ma, Bin1 (AUTHOR), Maw, Hlaing9 (AUTHOR), Miller, Grover P.10 (AUTHOR), Seneviratne, Herana Kamal11 (AUTHOR), Takahashi, Ryan H.12 (AUTHOR), Wei, Cong13 (AUTHOR), Khojasteh, S. Cyrus1 (AUTHOR) pars@gene.com, Lang, D. (AUTHOR), Schulz, S. (AUTHOR)
Publikováno v:
Drug Metabolism Reviews. Nov2023, Vol. 55 Issue 4, p267-300. 34p.