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pro vyhledávání: '"Monteiro, Pedro T."'
Autor:
Cury, José E. R., Roxo, Patrícia Tenera, Manquinho, Vasco, Chaouiya, Claudine, Monteiro, Pedro T.
Boolean networks constitute relevant mathematical models to study the behaviours of genetic and signalling networks. These networks define regulatory influences between molecular nodes, each being associated to a Boolean variable and a regulatory (lo
Externí odkaz:
http://arxiv.org/abs/2407.01337
Publikováno v:
Journal of Theoretical Biology 109 (2022)
Computational models of biological processes provide one of the most powerful methods for a detailed analysis of the mechanisms that drive the behavior of complex systems. Logic-based modeling has enhanced our understanding and interpretation of thos
Externí odkaz:
http://arxiv.org/abs/2104.01279
Logical models have been successfully used to describe regulatory and signaling networks without requiring quantitative data. However, existing data is insufficient to adequately define a unique model, rendering the parametrization of a given model a
Externí odkaz:
http://arxiv.org/abs/1901.07623
Publikováno v:
In BioSystems September 2021 207
Publikováno v:
In Computer Methods and Programs in Biomedicine August 2020 192
Akademický článek
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Motivation: Models of discrete concurrent systems often lead to huge and complex state transition graphs that represent their dynamics. This makes difficult to analyse dynamical properties. In particular, for logical models of biological regulatory n
Externí odkaz:
http://arxiv.org/abs/1411.3539
Autor:
Chaouiya, Claudine, Berenguier, Duncan, Keating, Sarah M, Naldi, Aurelien, van Iersel, Martijn P., Rodriguez, Nicolas, Dräger, Andreas, Büchel, Finja, Cokelaer, Thomas, Kowal, Bryan, Wicks, Benjamin, Gonçalves, Emanuel, Dorier, Julien, Page, Michel, Monteiro, Pedro T., von Kamp, Axel, Xenarios, Ioannis, de Jong, Hidde, Hucka, Michael, Klamt, Steffen, Thieffry, Denis, Novère, Nicolas Le, Saez-Rodriguez, Julio, Helikar, Tomáš
Background: Qualitative frameworks, especially those based on the logical discrete formalism, are increasingly used to model regulatory and signalling networks. A major advantage of these frameworks is that they do not require precise quantitative da
Externí odkaz:
http://arxiv.org/abs/1309.1910
Publikováno v:
In IFAC PapersOnLine 2019 52(26):38-44
Publikováno v:
In Operations Research Perspectives 2019 6