Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation.

Autor: Ruggeri Barbaro N; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., Van Beusecum J; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., Xiao L; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., do Carmo L; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., Pitzer A; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., Loperena R; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Foss JD; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., Elijovich F; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., Laffer CL; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., Montaniel KR; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., Galindo CL; Division of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Chen W; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., Ao M; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., Mernaugh RL; Department of Biochemistry, Vanderbilt University, Nashville, TN, USA., Alsouqi A; Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Ikizler TA; Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Fogo AB; Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Moreno H; Department of Intern Medicine, Faculty of Medical Sciences, Cardiovascular Pharmacology Laboratory, University of Campinas, Campinas, Brazil., Zhao S; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Davies SS; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA., Harrison DG; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Kirabo A; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2021 Apr 23; Vol. 117 (5), pp. 1358-1371.

CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli.

Autor: Itani HA; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Xiao L; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Saleh MA; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Wu J; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Pilkinton MA; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Dale BL; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Barbaro NR; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Foss JD; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Kirabo A; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Montaniel KR; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Norlander AE; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Chen W; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Sato R; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Navar LG; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Mallal SA; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Madhur MS; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Bernstein KE; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA., Harrison DG; From the Division of Clinical Pharmacology, Department of Medicine (H.A.I., L.X., M.A.S., J.W., B.L.D., J.D.F., A.K., K.R.M., A.E.N., W.C., M.S.M., D.G.H.) and Division of Infectious Diseases (M.A.P., S.A.M.), Vanderbilt University Medical Center, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Laboratory of Cardiovascular Pharmacology, Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil (N.R.B.); Department of Physiology and Hypertension and Renal Center, School of Medicine, Tulane University, New Orleans, LA (R.S., L.G.N.); and Departments of Biomedical Sciences (K.E.B.) and Pathology and Laboratory Medicine (K.E.B.), Cedars-Sinai Medical Center, Los Angeles, CA. david.g.harrison@vanderbilt.edu.

Publikováno v: Circulation research [Circ Res] 2016 Apr 15; Vol. 118 (8), pp. 1233-43. Date of Electronic Publication: 2016 Mar 17.

Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension.

Autor: Wu J; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.)., Montaniel KR; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.)., Saleh MA; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.)., Xiao L; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.)., Chen W; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.)., Owens GK; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.)., Humphrey JD; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.)., Majesky MW; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.)., Paik DT; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.)., Hatzopoulos AK; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.)., Madhur MS; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.)., Harrison DG; From the Division of Clinical Pharmacology, Department of Medicine (J.W., K.R.C.M., M.A.S., L.X., W.C., M.S.M., D.G.H.), Department of Molecular Physiology and Biophysics (K.R.C.M., M.S.M., D.G.H.), Division of Cardiovascular Medicine, Department of Medicine (D.T.P., A.K.H.), and Department of Cell and Developmental Biology (D.T.P., A.K.H.), School of Medicine, Vanderbilt University, Nashville, TN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt (M.A.S.); Robert M. Berne Cardiovascular Research Center, Department of Physiology, University of Virginia, Charlottesville (G.K.O.); Department of Biomedical Engineering, Yale University, New Haven, CT (J.D.H.); Vascular Biology and Therapeutics Program, Yale School of Medicine, New Haven, CT (J.D.H.); Seattle Children's Research Institute, WA (M.W.M.). david.g.harrison@vanderbilt.edu.

Publikováno v: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2016 Feb; Vol. 67 (2), pp. 461-8. Date of Electronic Publication: 2015 Dec 22.

Phage-display-guided nanocarrier targeting to atheroprone vasculature.

Autor: Hofmeister LH; †Department of Biomedical Engineering, ‡Division of Clinical Pharmacology, §Center for Vascular Biology, and ∥Division of Cardiovascular Medicine, Vanderbilt University, Nashville, Tennessee 37235, United States., Lee SH; †Department of Biomedical Engineering, ‡Division of Clinical Pharmacology, §Center for Vascular Biology, and ∥Division of Cardiovascular Medicine, Vanderbilt University, Nashville, Tennessee 37235, United States., Norlander AE; †Department of Biomedical Engineering, ‡Division of Clinical Pharmacology, §Center for Vascular Biology, and ∥Division of Cardiovascular Medicine, Vanderbilt University, Nashville, Tennessee 37235, United States., Montaniel KR; †Department of Biomedical Engineering, ‡Division of Clinical Pharmacology, §Center for Vascular Biology, and ∥Division of Cardiovascular Medicine, Vanderbilt University, Nashville, Tennessee 37235, United States., Chen W; †Department of Biomedical Engineering, ‡Division of Clinical Pharmacology, §Center for Vascular Biology, and ∥Division of Cardiovascular Medicine, Vanderbilt University, Nashville, Tennessee 37235, United States., Harrison DG; †Department of Biomedical Engineering, ‡Division of Clinical Pharmacology, §Center for Vascular Biology, and ∥Division of Cardiovascular Medicine, Vanderbilt University, Nashville, Tennessee 37235, United States., Sung HJ; †Department of Biomedical Engineering, ‡Division of Clinical Pharmacology, §Center for Vascular Biology, and ∥Division of Cardiovascular Medicine, Vanderbilt University, Nashville, Tennessee 37235, United States.

Publikováno v: ACS nano [ACS Nano] 2015; Vol. 9 (4), pp. 4435-46. Date of Electronic Publication: 2015 Mar 23.

Vascular biomechanical properties in mice with smooth muscle specific deletion of Ndst1.

Autor: Adhikari N; Lillehei Heart Institute, Department of Medicine, University of Minnesota, 4-106 NHH, 312 Church St. SE, Minneapolis, MN, 55455, USA., Billaud M, Carlson M, Lake SP, Montaniel KR, Staggs R, Guan W, Walek D, Desir S, Isakson BE, Barocas VH, Hall JL

Publikováno v: Molecular and cellular biochemistry [Mol Cell Biochem] 2014 Jan; Vol. 385 (1-2), pp. 225-38. Date of Electronic Publication: 2013 Oct 08.