Posttraumatic Stress Disorder, Obesity, and Accelerated Epigenetic Aging Among US Military Veterans.

Autor: Fischer IC; US Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, VA Connecticut Healthcare System, West Haven.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut., Na PJ; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.; VA Connecticut Healthcare System, West Haven, Connecticut., Nagamatsu ST; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.; VA Connecticut Healthcare System, West Haven, Connecticut., Jeste DV; Global Research Network on Social Determinants of Mental Health and Exposomics, La Jolla, California., Cabrera-Mendoza B; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.; VA Connecticut Healthcare System, West Haven, Connecticut., Montalvo-Ortiz JL; US Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, VA Connecticut Healthcare System, West Haven.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut., Krystal JH; US Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, VA Connecticut Healthcare System, West Haven.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut., Polimanti R; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.; VA Connecticut Healthcare System, West Haven, Connecticut., Gelernter J; US Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, VA Connecticut Healthcare System, West Haven.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut., Pietrzak RH; US Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, VA Connecticut Healthcare System, West Haven.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.; Department of Social and Behavioral Sciences, Yale School of Public Health, New Haven, Connecticut.

Publikováno v: JAMA psychiatry [JAMA Psychiatry] 2024 Oct 30. Date of Electronic Publication: 2024 Oct 30.

Multi-omics profiling of DNA methylation and gene expression alterations in human cocaine use disorder.

Autor: Zillich E; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Belschner H; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Avetyan D; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Andrade-Brito D; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; VA CT Healthcare Center, West Haven, CT, USA., Martínez-Magaña JJ; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; VA CT Healthcare Center, West Haven, CT, USA., Frank J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Mechawar N; McGill Group for Suicide Studies, Douglas Mental Health University Institute, Montreal, QC, Canada.; Department of Psychiatry, McGill University, Montreal, QC, Canada., Turecki G; McGill Group for Suicide Studies, Douglas Mental Health University Institute, Montreal, QC, Canada.; Department of Psychiatry, McGill University, Montreal, QC, Canada., Cabana-Domínguez J; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain., Fernàndez-Castillo N; Department de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, and Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Catalonia, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Institut de Recerca Sant Joan de Déu (IR-SJD), Esplugues de Llobregat, Barcelona, Catalonia, Spain., Cormand B; Department de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, and Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Catalonia, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Institut de Recerca Sant Joan de Déu (IR-SJD), Esplugues de Llobregat, Barcelona, Catalonia, Spain., Montalvo-Ortiz JL; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; VA CT Healthcare Center, West Haven, CT, USA.; US Department of Veterans Affairs National Center of Posttraumatic Stress Disorder, Clinical Neurosciences Division, West Haven, CT, USA., Nöthen MM; Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany., Hansson AC; Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Rietschel M; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Spanagel R; Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Center for Mental Health (DZPG), partner site Mannheim/Heidelberg/Ulm, Mannheim, Germany., Witt SH; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. stephanie.witt@zi-mannheim.de.; German Center for Mental Health (DZPG), partner site Mannheim/Heidelberg/Ulm, Mannheim, Germany. stephanie.witt@zi-mannheim.de.; Center for Innovative Psychiatric and Psychotherapeutic Research, Biobank, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. stephanie.witt@zi-mannheim.de., Zillich L; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; German Center for Mental Health (DZPG), partner site Mannheim/Heidelberg/Ulm, Mannheim, Germany.; HITBR Hector Institute for Translational Brain Research gGmbH, Mannheim, Germany.

Publikováno v: Translational psychiatry [Transl Psychiatry] 2024 Oct 09; Vol. 14 (1), pp. 428. Date of Electronic Publication: 2024 Oct 09.

Towards a Novel Frontier in the Use of Epigenetic Clocks in Epidemiology.

Autor: Martínez-Magaña JJ; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; U.S. Department of Veterans Affairs National Center for Post-Traumatic Stress Disorder, Clinical Neuroscience Division, West Haven, CT, USA; VA Connecticut Healthcare System, West Haven, CT, USA., Hurtado-Soriano J; Dirección de Investigación, Instituto Nacional de Geriatría, Mexico City, Mexico., Rivero-Segura NA; Dirección de Investigación, Instituto Nacional de Geriatría, Mexico City, Mexico., Montalvo-Ortiz JL; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; U.S. Department of Veterans Affairs National Center for Post-Traumatic Stress Disorder, Clinical Neuroscience Division, West Haven, CT, USA; VA Connecticut Healthcare System, West Haven, CT, USA., Garcia-delaTorre P; Unidad de Investigación Epidemiológica y en Servicios de Salud, Área de Envejecimiento, Centro Médico Nacional, Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Becerril-Rojas K; Dirección de Investigación, Instituto Nacional de Geriatría, Mexico City, Mexico., Gomez-Verjan JC; Dirección de Investigación, Instituto Nacional de Geriatría, Mexico City, Mexico. Electronic address: jverjan@inger.gob.mx.

Publikováno v: Archives of medical research [Arch Med Res] 2024 Jul; Vol. 55 (5), pp. 103033. Date of Electronic Publication: 2024 Jul 01.

Neuronal-specific methylome and hydroxymethylome analysis reveal significant loci associated with alcohol use disorder.

Autor: Andrade-Brito DE; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States.; National Center of Post-Traumatic Stress Disorder, VA CT Healthcare, West Haven, CT, United States., Núñez-Ríos DL; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States.; National Center of Post-Traumatic Stress Disorder, VA CT Healthcare, West Haven, CT, United States., Martínez-Magaña JJ; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States.; National Center of Post-Traumatic Stress Disorder, VA CT Healthcare, West Haven, CT, United States., Nagamatsu ST; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States.; National Center of Post-Traumatic Stress Disorder, VA CT Healthcare, West Haven, CT, United States., Rompala G; Icahn School of Medicine at Mount Sinai, New York City, NY, United States., Zillich L; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Witt SH; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Clark SL; Department of Psychiatry and Behavioral Sciences, Texas A&M University, College Station, TX, United States., Lattig MC; Facultad de Ciencias, Universidad de los Andes, Bogotá, Colombia., Montalvo-Ortiz JL; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States.; National Center of Post-Traumatic Stress Disorder, VA CT Healthcare, West Haven, CT, United States.

Publikováno v: Frontiers in genetics [Front Genet] 2024 Apr 03; Vol. 15, pp. 1345410. Date of Electronic Publication: 2024 Apr 03 (Print Publication: 2024).

Psychosocial moderators of polygenic risk scores of inflammatory biomarkers in relation to GrimAge.

Autor: Tamman AJF; Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA. amanda.tamman@bcm.edu., Koller D; Division of Human Genetics, Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Nagamatsu S; Division of Human Genetics, Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Cabrera-Mendoza B; Division of Human Genetics, Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Abdallah C; Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Krystal JH; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; U.S. Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, CT, USA., Gelernter J; Division of Human Genetics, Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; U.S. Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, CT, USA., Montalvo-Ortiz JL; Division of Human Genetics, Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; U.S. Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, CT, USA., Polimanti R; Division of Human Genetics, Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Pietrzak RH; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; U.S. Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, CT, USA.; Department of Social and Behavioral Sciences, Yale School of Public Health, New Haven, CT, USA.

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2024 Mar; Vol. 49 (4), pp. 699-708. Date of Electronic Publication: 2023 Oct 17.