NBS1 binds directly to TOPBP1 via disparate interactions between the NBS1 BRCT1 domain and the TOPBP1 BRCT1 and BRCT2 domains

Autor: Huynh, Oanh, Ruis, Kenna, Montales, Katrina, Michael, W. Matthew

Publikováno v: In DNA Repair March 2023 123

Biochemical analysis of TOPBP1 oligomerization

Autor: Kim, Ahhyun, Montales, Katrina, Ruis, Kenna, Senebandith, Holly, Gasparyan, Hovik, Cowan, Quinn, Michael, W. Matthew ^*

Publikováno v: In DNA Repair December 2020 96

MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks.

Autor: Montales, Katrina¹ (AUTHOR), Ruis, Kenna¹ (AUTHOR), Lindsay, Howard² (AUTHOR), Michael, W. Matthew¹ (AUTHOR) mattm@usc.edu

Publikováno v: PLoS ONE. 8/2/2022, Vol. 17 Issue 8, p1-18. 18p.

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The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis.

Autor: Acevedo A; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, USA., Jones AE; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, USA., Danna BT; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, USA., Turner R; School of Agriculture and Food Science, University College Dublin, Dublin, Ireland., Montales KP; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Benincá C; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Reue K; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Shirihai OS; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Stiles L; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Wallace M; School of Agriculture and Food Science, University College Dublin, Dublin, Ireland., Wang Y; DukeNUS School of Medicine, Signature Research Program in Cardiovascular and Metabolic Diseases, 8 College Road, Mail Code 169857, Singapore., Bertholet AM; Department of Physiology, University of California, Los Angeles, Los Angeles, CA, USA., Divakaruni AS; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, USA.; Lead contact.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Aug 16. Date of Electronic Publication: 2023 Aug 16.