Decline in corepressor CNOT1 in the pregnant myometrium near term impairs progesterone receptor function and increases contractile gene expression.

Autor: Kwak YT; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas, USA., Montalbano AP; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, Texas, USA., Kelleher AM; Department of Obstetrics & Gynecology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA; Laboratory of Signaling and Gene Regulation, The University of Texas Southwestern Medical Center, Dallas, Texas, USA; Cecil H. and Ida Green Center for Reproductive Biology Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Obstetrics, Gynecology, and Women's Health, University of Missouri, Columbia, Missouri, USA., Colon-Caraballo M; Department of Obstetrics & Gynecology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA; Cecil H. and Ida Green Center for Reproductive Biology Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas, USA., Kraus WL; Laboratory of Signaling and Gene Regulation, The University of Texas Southwestern Medical Center, Dallas, Texas, USA; Cecil H. and Ida Green Center for Reproductive Biology Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas, USA., Mahendroo M; Department of Obstetrics & Gynecology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA; Cecil H. and Ida Green Center for Reproductive Biology Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas, USA. Electronic address: mala.mahendroo@utsouthwestern.edu., Mendelson CR; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Obstetrics & Gynecology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA; Cecil H. and Ida Green Center for Reproductive Biology Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas, USA; North Texas March of Dimes Birth Defects Center, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 Jul; Vol. 300 (7), pp. 107484. Date of Electronic Publication: 2024 Jun 18.

Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome.

Autor: Chu H; Center for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.)., Sacharidou A; Center for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.)., Nguyen A; Center for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.)., Li C; Center for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.)., Chambliss KL; Center for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.)., Salmon JE; Medicine, Hospital for Special Surgery, Weill Cornell Medical College, New York (J.E.S.)., Shen YM; Internal Medicine (Y.-M.S., D.K.M.), University of Texas Southwestern Medical Center, Dallas., Lo J; Obstetrics and Gynecology (J.L.), University of Texas Southwestern Medical Center, Dallas., Leone GW; Froedtert-Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, Milwaukee (G.W.L.)., Herz J; Molecular Genetics (J.H.), University of Texas Southwestern Medical Center, Dallas., Hui DY; Pathology, University of Cincinnati College of Medicine (D.Y.H.)., Marciano DK; Internal Medicine (Y.-M.S., D.K.M.), University of Texas Southwestern Medical Center, Dallas.; Cell Biology (D.K.M., C.M.), University of Texas Southwestern Medical Center, Dallas., Abrahams VM; Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, New Haven, CT (V.M.A.)., Natale BV; Obstetrics, Gynecology & Reproductive Science, University of California San Diego, La Jolla (B.V.N., D.R.N.).; Obstetrics and Gynaecology, School of Medicine, Queen's University, Ontario, Canada (B.V.N., D.R.N.)., Montalbano AP; Biochemistry and Obstetrics and Gynecology (A.P.M.), University of Texas Southwestern Medical Center, Dallas., Xiao X; Population and Data Sciences and Pediatrics (X.X., L.X.), University of Texas Southwestern Medical Center, Dallas., Xu L; Population and Data Sciences and Pediatrics (X.X., L.X.), University of Texas Southwestern Medical Center, Dallas., Natale DR; Obstetrics, Gynecology & Reproductive Science, University of California San Diego, La Jolla (B.V.N., D.R.N.).; Obstetrics and Gynaecology, School of Medicine, Queen's University, Ontario, Canada (B.V.N., D.R.N.)., Shaul PW; Center for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.)., Mineo C; Center for Pulmonary and Vascular Biology, Pediatrics (H.C., A.S., A.N., C.L., K.L.C., P.W.S., C.M.).; Cell Biology (D.K.M., C.M.), University of Texas Southwestern Medical Center, Dallas.

Publikováno v: Circulation research [Circ Res] 2021 Sep 17; Vol. 129 (7), pp. 735-750. Date of Electronic Publication: 2021 Aug 18.

The transcriptional repressor GATAD2B mediates progesterone receptor suppression of myometrial contractile gene expression.

Autor: Chen CC; Department of Biochemistry and the Department of Obstetrics and Gynecology, North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038., Montalbano AP; Department of Biochemistry and the Department of Obstetrics and Gynecology, North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038., Hussain I; Department of Biochemistry and the Department of Obstetrics and Gynecology, North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038., Lee WR; Department of Biochemistry and the Department of Obstetrics and Gynecology, North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038., Mendelson CR; Department of Biochemistry and the Department of Obstetrics and Gynecology, North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038. Electronic address: carole.mendelson@utsouthwestern.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2017 Jul 28; Vol. 292 (30), pp. 12560-12576. Date of Electronic Publication: 2017 Jun 02.

Molecular Regulation of Parturition: A Myometrial Perspective.

Autor: Renthal NE; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038., Williams KC; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038., Montalbano AP; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038., Chen CC; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038., Gao L; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038., Mendelson CR; Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038 Department of Obstetrics-Gynecology, North Texas March of Dimes Birth Defects Center, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038.

Publikováno v: Cold Spring Harbor perspectives in medicine [Cold Spring Harb Perspect Med] 2015 Sep 03; Vol. 5 (11). Date of Electronic Publication: 2015 Sep 03.