Výsledky vyhledávání

Connectomic-genetic signatures in the cerebral small vessel disease

Autor: Gutiérrez-Zúñiga R., Diez I., Bueichekú E., Kim C.-M., Orwig W., Montal V., Fuentes B., Díez-Tejedor E., Fernández M.G., Sepulcre J.

Publikováno v: NEUROBIOLOGY OF DISEASE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Small vessel disease (SVD) is a disorder that causes vascular lesions in the entire parenchyma of the human brain. At present, it is not well understood how primary and secondary damage interact to give rise to the complex scenario of white matter (W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::f216c6a75a565345f21033887f840cdd
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=10313

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Pathophysiological Underpinnings of Extra-Motor Neurodegeneration in Amyotrophic Lateral Sclerosis: New Insights From Biomarker Studies

Autor: Reyes-Leiva, D, Dols-Icardo, O, Sirisi, S, Cortes-Vicente, E, Turon-Sans, J, De Luna, N, Blesa, R, Belbin, O, Montal, V, Alcolea, D, Fortea, J, Lleo, A, Rojas-Garcia, R, Illan-Gala, I

Publikováno v: Frontiers in Neurology
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) lie at opposing ends of a clinical, genetic, and neuropathological continuum. In the last decade, it has become clear that cognitive and behavioral changes in patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::ff7edc47437b650a0c57f10c803d5d83
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=7693

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Metabolite Signature of Alzheimer's Disease in Adults with Down Syndrome

Autor: Montal, V, Barroeta, I, Bejanin, A, Pegueroles, J, Carmona-Iragui, M, Altuna, M, Benejam, B, Videla, L, Fernandez, S, Padilla, C, Aranha, MR, Iulita, MF, Vidal-Pineiro, D, Alcolea, D, Blesa, R, Lleo, A, Fortea, J

Publikováno v: ANNALS OF NEUROLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Objective The purpose of this study was to examine the Alzheimer's disease metabolite signature through magnetic resonance spectroscopy in adults with Down syndrome and its relation with Alzheimer's disease biomarkers and cortical thickness. Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::ed2ed9a3e77f290e7db9edc54adc6a7c
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=5480

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Multilingualism in semantic dementia: language-dependent lexical retrieval from degraded conceptual representations

Autor: Calabria, M, Jefferies, E, Sala, I, Morenas-Rodriguez, E, Illan-Gala, I, Montal, V, Fortea, J, Lleo, A, Costa, A

Publikováno v: APHASIOLOGY
r-IIB SANT PAU: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut dInvestigació Biomèdica Sant Pau (IIB Sant Pau)
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Background: Patients with the semantic variant of Primary Progressive Aphasia (svPPA) offer a unique opportunity to study the relationship between lexical retrieval and semantics, as they are characterised by progressive degradation of central semant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c4dd0c7c8fc896982ee064cd53c1b89b
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=1460

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Association of cortical microstructure with amyloid-beta and tau: impact on cognitive decline, neurodegeneration, and clinical progression in older adults

Autor: Rodriguez-Vieitez, E, Montal, V, Sepulcre, J, Lois, C, Hanseeuw, B, Vilaplana, E, Schultz, AP, Properzi, MJ, Scott, MR, Amariglio, R, Papp, KV, Marshall, GA, Fortea, J, Johnson, KA, Sperling, RA, Vannini, P

Publikováno v: MOLECULAR PSYCHIATRY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Noninvasive biomarkers of early neuronal injury may help identify cognitively normal individuals at risk of developing Alzheimer's disease (AD). A recent diffusion-weighted imaging (DWI) method allows assessing cortical microstructure via cortical me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::e5b73935bd3e75e9afce27e5afe1c76a
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4334

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Akademický článek

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APP-derived peptides reflect neurodegeneration in frontotemporal dementia

Autor: Illan-Gala, I, Pegueroles, J, Montal, V, Alcolea, D, Vilaplana, E, Bejanin, A, Borrego-Ecija, S, Sampedro, F, Subirana, A, Sanchez-Saudinos, MB, Rojas-Garcia, R, Vanderstichele, H, Blesa, R, Clarimon, J, Antonell, A, Llado, A, Sanchez-Valle, R, Fortea, J, Lleo, A

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Annals of Clinical and Translational Neurology
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Altres ajuts: The Catalan frontotemporal initiative (CATFI) is funded by the Health Department of the Government of Catalonia (grant PERIS SLT002/16/00408 to Alberto Lleó and Raquel Sánchez-Valle). This work was also supported by research grants fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::36113368d19563dc91ae3756a886dc45
https://ddd.uab.cat/record/222804

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CSF sAPP beta, YKL-40, and NfL along the ALS-FTD spectrum

Autor: Illan-Gala, I, Alcolea, D, Montal, V, Dols-Icardo, O, Munoz, L, de Luna, N, Turon-Sans, J, Cortes-Vicente, E, Sanchez-Saudinos, MB, Subirana, A, Sala, I, Blesa, R, Clarimon, J, Fortea, J, Rojas-Garcia, R, Lleo, A

Publikováno v: NEUROLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Objective To investigate the clinical utility of 3 CSF biomarkers along the clinical spectrum of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Methods We analyzed 3 CSF biomarkers: the soluble beta-fragment of amyloid precurs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::d4f1608d3166a59484ca20ed0e6c3068
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=3330

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Obesity and Alzheimer's disease, does the obesity paradox really exist? A magnetic resonance imaging study

Autor: Pegueroles J., Jiménez A., Vilaplana E., Montal V., Carmona-Iragui M., Pané A., Alcolea D., Videla L., Casajoana A., Clarimón J., Ortega E., Vidal J., Blesa R., Lleó A., Fortea J.

Publikováno v: Oncotarget
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Mid-life obesity is an established risk factor for Alzheimer's disease (AD) dementia,whereas late-life obesity has been proposed as a protective state. Weight loss, whichpredates cognitive decline, might explain this obesity paradox on AD risk. We ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::0d19ea04bdd5973900b4a4222e886f97
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=10185

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