Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Monroe S. Glitzer"'
Autor:
Frederick W. Holly, Ruth F. Nutt, Marylou Torchiana, William J. Paleveda, Richard Saperstein, Monroe S. Glitzer, Susan J. Bergstrand, Daniel F. Veber, Ralph Hirschmann
Publikováno v:
Proceedings of the National Academy of Sciences. 75:2636-2640
A model for a biologically active conformation of somatostatin is proposed. This model is based primarily on the biological results obtained with novel bicyclic somatostatin analogs having a covalent bridge replacing the side chains of residues 5 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22cd03c998bd02c6ab03307b4e499e86
https://doi.org/10.1073/pnas.75.6.2636
https://doi.org/10.1073/pnas.75.6.2636
Autor:
Mitree M. Ponpipom, T. Y. Shen, Monroe S. Glitzer, Robert L. Bugianesi, Philippe L. Durette, Howard M. Katzen, Margaret A. Cascieri
Publikováno v:
Journal of Medicinal Chemistry. 21:854-859
A number of alkyl, aryl, and aralkyl glycosides (mono- and disaccharides) substituted in the aglycon with a primary amino group have been found to exert insulin-like activity on rat adipocytes in vitro. Systematic variations in the saccharide configu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f2def7705618c46e7866663c68c7de
https://doi.org/10.1021/jm00207a003
https://doi.org/10.1021/jm00207a003
Publikováno v:
Steroids. 18:129-139
6,16α-Dimethyl-4, 6-pregnadiene-11β, 17, 21-triol-20-one phenylpyrazole-21-acetate and its 21-desoxy derivative were evaluated in animals and in man for glucocorticoid activity. These compounds did not exhibit a significant separation of the biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9abb8951c16171b187ff42b849d5c985
https://doi.org/10.1016/0039-128x(71)90020-1
https://doi.org/10.1016/0039-128x(71)90020-1
Autor:
Monroe S. Glitzer, Sanford L. Steelman
Publikováno v:
Experimental Biology and Medicine. 120:364-367
SummaryN-amidino-3-amino-6-chloropy-razinecarboxamide (ACP) was found to: 1) antagonize the renal actions of exogenously administered aldosterone, DCA and hydrocortisone in the adrenalectomized rat, 2) reverse the action of endogenously produced aldo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ecdc9c0b3af14b2d5399fbf12d0ff2
https://doi.org/10.3181/00379727-120-30538
https://doi.org/10.3181/00379727-120-30538
Autor:
Ruth F. Nutt, Ralph Hisrschmann, Stephen F. Brady, Richard Saperstein, D. F. Veber, Monroe S. Glitzer, Frederick W. Holly, Susan J. Bergstrand
Publikováno v:
Nature. 280:512-514
THE biological activity of an organic compound represents the sum of several properties, including solubility, absorption, transport, plasma protein binding, metabolism and receptor binding. The degree of molecular flexibility may affect these proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7606cb0cd7b3a73a7920104f9f429b2a
https://doi.org/10.1038/280512a0
https://doi.org/10.1038/280512a0
Autor:
Ruth F. Nutt, Debra S. Perlow, Daniel F. Veber, William J. Paleveda, Richard Saperstein, Carl F. Homnick, Robert G. Strachan, Byron H. Arison, Hirschmann Ralph F, Monroe S. Glitzer, Frederick W. Holly, Freidlinger Rm, W.C. Randall
Publikováno v:
Nature. 292(5818)
Conformational analysis has resulted in the design and synthesis of somatostatin analogues which show increased duration of action1–3. The introduction of covalent conformational constraints and elimination of amino acids that are not required led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729e01f9ed89bd0ab559337ad94c426b
https://pubmed.ncbi.nlm.nih.gov/6116194
https://pubmed.ncbi.nlm.nih.gov/6116194
Autor:
Monroe S. Glitzer, Sanford L. Steelman
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 138(2)
Mueller and Reed (1) have reported that the implantation of S. mansonoides spargana in normally growing rats did not enhance body weight gain. This was in contrast to their findings of marked weight gain in normal mice, hamsters, and hypothyroid and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bfa4f6cc8eb4914ca8b44adc7735274
https://pubmed.ncbi.nlm.nih.gov/5118474
https://pubmed.ncbi.nlm.nih.gov/5118474
Publisher Summary This chapter presents a comparative study of the properties of sparganum growth factor (SGF) and growth hormone. Tapeworms of the genus Spirometra are of medical interest, in that the larval form is occasionally found as a tissue pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb71a10ed6146a6c31a5c3ee06745306
https://doi.org/10.1016/b978-0-12-571127-2.50027-4
https://doi.org/10.1016/b978-0-12-571127-2.50027-4
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 133(1)
SummaryThe subcutaneous implantation of Spirometra mansonoides spargana into hypophysectomized rats produced a striking increase in body weight and tibial cartilage width comparable to that noted with growth hormone. Other tissue responses confirmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83e28ba936c1df08d8d4d953de4f038
https://pubmed.ncbi.nlm.nih.gov/5412344
https://pubmed.ncbi.nlm.nih.gov/5412344