COVID-19 Causes Ciliary Dysfunction as Demonstrated by Human Intranasal Micro-Optical Coherence Tomography Imaging.

Autor: Vijaykumar, Kadambari, Hui Min Leung, Barrios, Amilcar, Fernandez-Petty, Courtney M., Solomon, George M., Hathorne, Heather Y., Wade, Justin D., Monroe, Kathryn, Slaten, Katie Brand, Qian Li, Leal Jr., Sixto M., Moates, Derek B., Pierce, Hannah M., Olson, Kristian R., Currier, Paul, Foster, Sam, Marsden, Doug, Tearney, Guillermo J., Rowe, Steven M.

Publikováno v: American Journal of Respiratory Cell & Molecular Biology; Nov2023, Vol. 69 Issue 5, p592-595, 16p

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Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

Autor: Logan, Todd, Simon, Matthew J., Rana, Anil, Cherf, Gerald M., Srivastava, Ankita, Davis, Sonnet S., Yoon Low, Ray Lieh, Chiu, Chi-Lu, Fang, Meng, Huang, Fen, Bhalla, Akhil, Llapashtica, Ceyda, Prorok, Rachel, Pizzo, Michelle E., Calvert, Meredith E.K., Sun, Elizabeth W., Hsiao-Nakamoto, Jennifer, Rajendra, Yashas, Lexa, Katrina W., Srivastava, Devendra B., van Lengerich, Bettina, Wang, Junhua, Robles-Colmenares, Yaneth, Kim, Do Jin, Duque, Joseph, Lenser, Melina, Earr, Timothy K., Nguyen, Hoang, Chau, Roni, Tsogtbaatar, Buyankhishig, Ravi, Ritesh, Skuja, Lukas L., Solanoy, Hilda, Rosen, Howard J., Boeve, Bradley F., Boxer, Adam L., Heuer, Hilary W., Dennis, Mark S., Kariolis, Mihalis S., Monroe, Kathryn M., Przybyla, Laralynne, Sanchez, Pascal E., Meisner, Rene, Diaz, Dolores, Henne, Kirk R., Watts, Ryan J., Henry, Anastasia G., Gunasekaran, Kannan, Astarita, Giuseppe, Suh, Jung H., Lewcock, Joseph W., DeVos, Sarah L., Di Paolo, Gilbert

Publikováno v: In Cell 14 March 2024 187(6):1565-1566

Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region

Autor: Schlepckow, Kai, Monroe, Kathryn M, Kleinberger, Gernot, Cantuti‐Castelvetri, Ludovico, Parhizkar, Samira, Xia, Dan, Willem, Michael, Werner, Georg, Pettkus, Nadine, Brunner, Bettina, Sülzen, Alice, Nuscher, Brigitte, Hampel, Heike, Xiang, Xianyuan, Feederle, Regina, Tahirovic, Sabina, Park, Joshua I, Prorok, Rachel, Mahon, Cathal, Liang, Chun‐Chi, Shi, Ju, Kim, Do Jin, Sabelström, Hanna, Huang, Fen, Di Paolo, Gilbert, Simons, Mikael, Lewcock, Joseph W, Haass, Christian

Publikováno v: EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 4, Pp n/a-n/a (2020)
EMBO molecular medicine 12(4), e11227 (2020). doi:10.15252/emmm.201911227

Triggering receptor expressed on myeloid cells 2 (TREM2) is essential for the transition of homeostatic microglia to a disease‐associated microglial state. To enhance TREM2 activity, we sought to selectively increase the full‐length protein on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d7ebb645fe4c519de33e22b891f35597
http://europepmc.org/articles/PMC7136959