Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Monocytes/ metabolism"'
Autor:
Pairo-Castineira, Erola, Rawlik, Konrad, Bretherick, Andrew D, Qi, Ting, Wu, Yang, Nassiri, Isar, McConkey, Glenn A., Zechner, Marie, Klaric, Lucija, Griffiths, Fiona, Oosthuyzen, Wilna, Kousathanas, Athanasios, Richmond , Anne, Millar, Jonathan, Russell, Clark D, Malinauskas, Tomas, Thwaites, Ryan, Morrice, Kirstie, Keating, Sean, Maslove, David M, Nichol, Alistair D, Semple, Malcolm Gracie, Knight, Julian, Shankar-Hari, Manu, Summers, Charlotte, Hinds , Charles, Horby, Peter, Ling, Lowell, McAuley, Danny F., Montgomery, Hugh, Openshaw, Peter J.M., Begg, Colin, Walsh, Timothy S., Tenesa, Albert, Flores, Carlos, Riancho, Jose A., Rojas-Martinez, Augusto, Lapunzina, Pablo, Yang, Jian, Ponting, Chris P, Wilson, James F, Vitart, Veronique, Abedalthagafi, Malak S, Luchessi, Andre, Parra, Esteban J, Cruz, Raquel, Carracedo, Angel, Fawkes, Angie, Murphy, Lee, Rowan, Kathy, Pereira, Alexandre C, Law, Andy, Fairfax, Benjamin P, Clohisey Hendry, Sara, Baillie, J Kenneth
Publikováno v:
Pairo-Castineira, E, Rawlik, K, Bretherick, A D, Qi, T, Wu, Y, Nassiri, I, McConkey, G A, Zechner, M, Klaric, L, Griffiths, F, Oosthuyzen, W, Kousathanas, A, Richmond, A, Millar, J, Russell, C D, Malinauskas, T, Thwaites, R, Morrice, K, Keating, S, Maslove, D M, Nichol, A D, Semple, M G, Knight, J, Shankar-Hari, M, Summers, C, Hinds, C, Horby, P, Ling, L, McAuley, D F, Montgomery, H, Openshaw, P J M, Begg, C, Walsh, T S, Tenesa, A, Flores, C, Riancho, J A, Rojas-Martinez, A, Lapunzina, P, Yang, J, Ponting, C P, Wilson, J F, Vitart, V, Abedalthagafi, M S, Luchessi, A, Parra, E J, Cruz, R, Carracedo, A, Fawkes, A, Murphy, L, Rowan, K, Pereira, A C, Law, A, Fairfax, B P, Clohisey Hendry, S & Baillie, J K 2023, ' GWAS and meta-analysis identifies 49 genetic variants underlying critical Covid-19 ', Nature, vol. 617, no. 7962, pp. 764-768 . https://doi.org/10.1038/s41586-023-06034-3
Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype that we have previously shown 1 to be highly efficient for discovery of genetic associations 2. Despite the advanced stage of illness at presentation, we have sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::43b7f0a3242c0f8452c02737c7d09b92
https://www.pure.ed.ac.uk/ws/files/348133266/s41586_023_06034_3.pdf
https://www.pure.ed.ac.uk/ws/files/348133266/s41586_023_06034_3.pdf
Autor:
Scott, Nicholas A, Pearmain, Laurence, Knight, Sean B, Brand, Oliver, Morgan, David J, Jagger, Christopher, Harbach, Sarah, Khan, Saba, Shuwa, Halima A, Franklin, Miriam, Kästele, Verena, Williams, Thomas, Prise, Ian, McClure, Flora A, Hackney, Pamela, Smith, Lara, Menon, Madhvi, Konkel, Joanne E, Lawless, Criag, Wilson, James, Mathioudakis, Aleaxander G, Stanel, Stefan C, Ustianowski, Andrew, Lindergard, Gabriella, Brij, Seema, Diar Bakerly, Nawar, Dark, Paul, Brightling, Christopher, Rivera-Ortega, Pilar, Lord, Graham M, Horsley, Alex, Piper Hanley, Karen, Felton, Timothy, Simpson, Angela, Grainger, John R, Hussell, Tracy, Mann, Elizabeth R
Publikováno v:
CIRCO 2023, ' Monocyte migration profiles define disease severity in acute COVID-19 and unique features of long COVID ', The European respiratory journal, vol. 61, no. 5 . https://doi.org/10.1183/13993003.02226-2022
CIRCO, Scott, N A, Pearmain, L, Knight, S B, Brand, O, Morgan, D J, Jagger, C, Harbach, S, Khan, S, Shuwa, H A, Franklin, M, Kästele, V, Williams, T, Prise, I, McClure, F A, Hackney, P, Smith, L, Menon, M, Konkel, J E, Lawless, C, Wilson, J, Mathioudakis, A G, Stanel, S C, Ustianowski, A, Lindergard, G, Brij, S, Diar Bakerly, N, Dark, P, Brightling, C, Rivera-Ortega, P, Lord, G M, Horsley, A, Piper Hanley, K, Felton, T, Simpson, A, Grainger, J R, Hussell, T & Mann, E R 2023, ' Monocyte migration profiles define disease severity in acute COVID-19 and unique features of long COVID ', The European respiratory journal, vol. 61, no. 5, 2202226 . https://doi.org/10.1183/13993003.02226-2022
CIRCO, Scott, N A, Pearmain, L, Knight, S B, Brand, O, Morgan, D J, Jagger, C, Harbach, S, Khan, S, Shuwa, H A, Franklin, M, Kästele, V, Williams, T, Prise, I, McClure, F A, Hackney, P, Smith, L, Menon, M, Konkel, J E, Lawless, C, Wilson, J, Mathioudakis, A G, Stanel, S C, Ustianowski, A, Lindergard, G, Brij, S, Diar Bakerly, N, Dark, P, Brightling, C, Rivera-Ortega, P, Lord, G M, Horsley, A, Piper Hanley, K, Felton, T, Simpson, A, Grainger, J R, Hussell, T & Mann, E R 2023, ' Monocyte migration profiles define disease severity in acute COVID-19 and unique features of long COVID ', The European respiratory journal, vol. 61, no. 5, 2202226 . https://doi.org/10.1183/13993003.02226-2022
BackgroundCOVID-19 is associated with a dysregulated immune response but it is unclear how immune dysfunction contributes to the chronic morbidity persisting in many COVID-19 patients during convalescence (long COVID).MethodsWe assessed phenotypical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c6b277a3f263f05db5519a491ef8da
https://research.manchester.ac.uk/en/publications/05869d52-b6e6-4b6a-a75b-53bf65f47e49
https://research.manchester.ac.uk/en/publications/05869d52-b6e6-4b6a-a75b-53bf65f47e49
Autor:
Máté Kiss, Els Lebegge, Aleksandar Murgaski, Helena Van Damme, Daliya Kancheva, Jan Brughmans, Isabelle Scheyltjens, Ali Talebi, Robin Maximilian Awad, Yvon Elkrim, Pauline M. R. Bardet, Sana M. Arnouk, Cleo Goyvaerts, Johan Swinnen, Frank Aboubakar Nana, Jo A. Van Ginderachter, Damya Laoui
Publikováno v:
Frontiers in immunology, Vol. 13, p. 1003975 (2022)
Máté Kiss
Máté Kiss
Junctional adhesion molecule-A (JAM-A), expressed on the surface of myeloid cells, is required for extravasation at sites of inflammation and may also modulate myeloid cell activation. Infiltration of myeloid cells is a common feature of tumors that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ce99f458cc212139567168893c2bf8
https://lirias.kuleuven.be/handle/20.500.12942/711752
https://lirias.kuleuven.be/handle/20.500.12942/711752
Publikováno v:
Scientific Reports. 12(1)
Coronary artery disease (CAD) is a long-lasting inflammatory disease characterized by monocyte migration into the vessel wall leading to clinical events like myocardial infarction (MI). However, the role of monocyte subsets, especially their miRNA-dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::085d51aa473d385cc20b57529de26d90
https://doi.org/10.1038/s41598-022-08600-7
https://doi.org/10.1038/s41598-022-08600-7
Autor:
Witten, Anika, Martens, Leonie, Schäfer, Ann-Christin, Troidl, Christian, Pankuweit, Sabine, Vlacil, Ann-Kathrin, Oberoi, Raghav, Schieffer, Bernhard, Grote, Karsten, Stoll, Monika, Markus, Birgit
Publikováno v:
Scientific Reports, 12(1):5589. Nature Publishing Group
Coronary artery disease (CAD) is a long-lasting inflammatory disease characterized by monocyte migration into the vessel wall leading to clinical events like myocardial infarction (MI). However, the role of monocyte subsets, especially their miRNA-dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::7eb7eff442d3ec6fa22a63645b60f465
https://cris.maastrichtuniversity.nl/en/publications/3982a2b9-3697-4629-9d1a-9562fac5d8d4
https://cris.maastrichtuniversity.nl/en/publications/3982a2b9-3697-4629-9d1a-9562fac5d8d4
Autor:
Stefan G.C. Mestrum, Eline M.P. Cremers, Norbert C.J. de Wit, Roosmarie J.M. Drent, Frans C.S. Ramaekers, Anton H.N. Hopman, Math P.G. Leers
Publikováno v:
Leukemia Research, 113
Leukemia Research, 113:106789. Elsevier Limited
Leukemia Research, 113:106789. Elsevier Limited
Contains fulltext : 251730.pdf (Publisher’s version ) (Open Access) BACKGROUND: Although flow cytometric detection of myelodysplastic syndrome (MDS) with the Ogata score has a high specificity, its sensitivity for low-grade MDS is low. Additional m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6aadf1b4272ed517c87a67ed33f3d1
https://doi.org/10.1016/j.leukres.2022.106789
https://doi.org/10.1016/j.leukres.2022.106789
Autor:
Elena Gardey, Fabian H. Sobotta, Stefanie Quickert, Tony Bruns, Johannes C. Brendel, Andreas Stallmach
Publikováno v:
Macromolecular bioscience : MBS 22(4), 2100482 (2022). doi:10.1002/mabi.202100482
Macromolecular Bioscience, 22(4):2100482. Wiley-VCH Verlag
Macromolecular Bioscience, 22(4):2100482. Wiley-VCH Verlag
Macromolecular bioscience : MBS 22(4), 2100482 (2022). doi:10.1002/mabi.202100482
Published by Wiley-VCH, Weinheim
Published by Wiley-VCH, Weinheim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1633f007472cd2f11b241ee721e4fd0
Autor:
Reijrink, M, van Ark, J, Lexis, C P H, Visser, L.M., Lodewijk, M E, van der Horst, I C C, Zeebregts, C J, van Goor, H, de Jager, S C A, Pasterkamp, G, Wolffenbuttel, B H R, Hillebrands, J L
Publikováno v:
Cardiovascular Diabetology, 21:72. BioMed Central Ltd.
Cardiovascular Diabetology, 21(1):72. BioMed Central Ltd
Cardiovascular Diabetology, 21(1):72. BioMed Central Ltd
Background Individuals with type 2 diabetes mellitus (T2DM) have an increased risk for developing macrovascular disease (MVD) manifested by atherosclerosis. Phenotypically and functionally different monocyte subsets (classical; CD14++CD16−, non-cla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcdf7ce6f0c7c7de65c44e44a7e1ab6e
https://pubmed.ncbi.nlm.nih.gov/35549955
https://pubmed.ncbi.nlm.nih.gov/35549955
Autor:
Eli Schwartz, Yoav Peleg, Alicia Rojas, Ariel Rudik, Hila Ben Ami Pilo, Ana Claudia Torrecilhas, Ziv Porat, Netta Nir, Or-Yam Revach, Dror Avni, Tal Havkin-Solomon, Abel Cruz Camacho, Thomas Zillinger, Andrew G. Bowie, Carmit Levy, Ron Rotkopf, Aryeh Solomon, Tal Block Tamin, Antonella Di Pizio, Paula Abou Karam, Reinat Nevo, Edo Kiper, Esther N. M. Nolte-‘t Hoen, Gunther Hartmann, Motti Gerlic, Rivka Dikstein, Anna Rivkin, Neils B. Quashie, Yifat Ofir-Birin, Neta Regev-Rudzki
Publikováno v:
Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Pathogens are thought to use host molecular cues to control when to initiate life-cycle transitions, but these signals are mostly unknown, particularly for the parasitic disease malaria caused by Plasmodium falciparum. The chemokine CXCL10 is present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1064e45a182dff5f26e2cfecc1f47d
https://dspace.library.uu.nl/handle/1874/416422
https://dspace.library.uu.nl/handle/1874/416422
Autor:
Peter Libby, Vanessa Frodermann, Friedrich Felix Hoyer, Christoph J. Binder, Christopher T. Chan, Annemijn F. Gregory, Yoshiko Iwamoto, Anne Vassalli, Cameron S. McAlpine, Matthias Nahrendorf, Atsushi Anzai, Filip K. Swirski, Thomas E. Scammell, Shun He, Florian Kahles, Wolfram C. Poller, Ashley M. Fenn, Mehdi Tafti, John E. Mindur, Colin Valet, Sara Rattik, Lennard Halle, M. Kiss
Publikováno v:
Nature
Nature, vol. 566, no. 7744, pp. 383-387
Nature, vol. 566, no. 7744, pp. 383-387
Sleep is integral to life 1 . Although insufficient or disrupted sleep increases the risk of multiple pathological conditions, including cardiovascular disease 2 , we know little about the cellular and molecular mechanisms by which sleep maintains ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce735b02272ecc0fdf0ecec71fd5eaa
http://europepmc.org/articles/PMC6442744
http://europepmc.org/articles/PMC6442744