Zobrazeno 1 - 10
of 3 596
pro vyhledávání: '"Monoamine transporter"'
Autor:
Ruiyue Zhao, Jinhua Chen, Ting Ye, Jianmin Chu, Jingwen Li, Yan Zhang, Siran Xu, Shaoyu Liu, Ling Chen, Karl Ploessl, David Alexoff, Hank F. Kung, Lin Zhu, Xinlu Wang
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Background In the central nervous system, type 2 vesicular monoamine transporters (VMAT2) are responsible for the reuptake of monoamines from synaptic junction back to pre-synaptic terminal vesicles. These transporters are functionally cruci
Externí odkaz:
https://doaj.org/article/c1d4787de487454aa9d814fece62d92d
Autor:
Yujie Yang, Xinyi Li, Jiaying Lu, Jingjie Ge, Mingjia Chen, Ruixin Yao, Mei Tian, Jian Wang, Fengtao Liu, Chuantao Zuo
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 1, Pp 93-106 (2023)
Nowadays, presynaptic dopaminergic positron emission tomography, which assesses deficiencies in dopamine synthesis, storage, and transport, is widely utilized for early diagnosis and differential diagnosis of parkinsonism. This review provides a comp
Externí odkaz:
https://doaj.org/article/453ee8b3183a42a8ae720e78594ab532
Autor:
Bianca Vlcek, Sylvie Dumas, Sara Ekmark-Lewén, Eleonora Rubino, Martin Ingelsson, Åsa Wallén-Mackenzie
Publikováno v:
Exploration of Neuroprotective Therapy, Vol 3, Iss 5, Pp 299-327 (2023)
Aim: Parkinson’s disease (PD) is characterized by degeneration of midbrain dopamine neurons and synucleinopathy [aggregated alpha-synuclein protein (αSyn)]. The correlation between αSyn pathology and dopamine neuron degeneration remains to be ful
Externí odkaz:
https://doaj.org/article/63b8257196c94393814fe8426fe8ee40
Autor:
Malik Alwindi, Ariege Bizanti
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e22413- (2023)
Vesicular monoamine transporters (VMATs) are key regulators of neurotransmitter release responsible for controlling numerous physiological, cognitive, emotional, and behavioral functions. They represent important therapeutic targets for numerous path
Externí odkaz:
https://doaj.org/article/1df0d0680c9141e7bf790568afab8e92
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17112 (2023)
All resolved high-resolution structures of the transporters in the neurotransmitter sodium symporter (NSS) family revealed that the NSS members share common structural and mechanistic features for substrate and ion binding and transport. However, a r
Externí odkaz:
https://doaj.org/article/60c7b52c3cf84db2a0ddf1f1191b2baf
Autor:
WANG Xixi, WAN Xinhua
Publikováno v:
Xiehe Yixue Zazhi, Vol 13, Iss 4, Pp 644-651 (2022)
Tardive dyskinesia(TD) is a kind of disabling movement disorder characterized by involuntary movements of the face, neck, extremities or trunk that results from long-term use of dopamine receptor blocking agents.The most common reason is the use of a
Externí odkaz:
https://doaj.org/article/68c35b0af2e5462ebbb7f5658a2f099a
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 4, Pp 104572- (2023)
The development of technetium-99m-labelled dihydrotetrabenazine (DTBZ) derivative for vesicular monoamine transporter 2 (VMAT2) tracing could be a benefit for single photon emission computed tomography (SPECT) imaging due to easy labelling chemistry
Externí odkaz:
https://doaj.org/article/afccd912248a451184f4021f449308e5
Autor:
Hyomin Ahn, Kichul Park, Dongyoung Kim, Sung-Gil Chi, Kee-Hyun Choi, Seo-Jung Han, Chiman Song
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2846 (2023)
Monoamine transporters, including dopamine, norepinephrine, and serotonin transporters (DAT, NET, and SERT, respectively), are important therapeutic targets due to their essential roles in the brain. To overcome the slow action of selective monoamine
Externí odkaz:
https://doaj.org/article/994692cf78634bf1a827887f379e9027
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Akademický článek
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