Pharmacokinetics of once-daily darunavir/ritonavir in second-line treatment in African children with HIV.

Autor: Tsirizani L; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.; Training and Research Unit of Excellence, Kamuzu University of Health Sciences, Blantyre, Malawi., Mohsenian Naghani S; Department of Pharmacy, Radboudumc Research Institute for Medical Innovation (RIMI), Radboud University Medical Center, Nijmegen, The Netherlands., Waalewijn H; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.; Department of Pharmacy, Radboudumc Research Institute for Medical Innovation (RIMI), Radboud University Medical Center, Nijmegen, The Netherlands., Szubert A; Medical Research Council Clinical Trials Unit at University College London, London, UK., Mulenga V; Department University Teaching Hospital, University of Lusaka, Lusaka, Zambia., Chabala C; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.; Department University Teaching Hospital, University of Lusaka, Lusaka, Zambia., Bwakura-Dangarembizi M; Department of Paediatrics and Child Health, Clinical Research Centre, University of Zimbabwe, Faculty of Medicine and Health Sciences, Harare, Zimbabwe.; Department of Child, Adolescent and Women's Health, University of Zimbabwe Faculty of Medicine and Health Sciences, Harare, Zimbabwe., Chitsamatanga M; Department of Paediatrics and Child Health, Clinical Research Centre, University of Zimbabwe, Faculty of Medicine and Health Sciences, Harare, Zimbabwe., Rutebarika DA; Department of Paediatrics, Joint Clinical Research Centre, Kampala, Uganda., Musiime V; Department of Paediatrics, Joint Clinical Research Centre, Kampala, Uganda.; Department of Paediatrics and Child Health, Makerere University, College of Health Sciences, School of Medicine, Kampala, Uganda., Kasozi M; Department of HIV Reasearch, Joint Clinical Research Centre, Mbarara, Uganda., Lugemwa A; Department of HIV Reasearch, Joint Clinical Research Centre, Mbarara, Uganda., Monkiewicz LN; Medical Research Council Clinical Trials Unit at University College London, London, UK., McIlleron HM; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.; Wellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Burger DM; Department of Pharmacy, Radboudumc Research Institute for Medical Innovation (RIMI), Radboud University Medical Center, Nijmegen, The Netherlands., Gibb DM; Medical Research Council Clinical Trials Unit at University College London, London, UK., Denti P; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Wasmann RE; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Colbers A; Department of Pharmacy, Radboudumc Research Institute for Medical Innovation (RIMI), Radboud University Medical Center, Nijmegen, The Netherlands.

Publikováno v: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2024 Nov 04; Vol. 79 (11), pp. 2990-2998.

First Pharmacokinetic Data of Tenofovir Alafenamide Fumarate and Tenofovir With Dolutegravir or Boosted Protease Inhibitors in African Children: A Substudy of the CHAPAS-4 Trial.

Autor: Waalewijn H; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands.; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, South Africa., Szubert AJ; Medical Research Council Clinical Trials Unit, University College London, United Kingdom., Wasmann RE; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, South Africa., Wiesner L; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, South Africa., Chabala C; Department of Paediatrics and Child Health, School of Medicine, University of Zambia.; Children's Hospital, University Teaching Hospital, Lusaka, Zambia., Bwakura-Dangarembizi M; University of Zimbabwe Clinical Research Centre, Harare., Makumbi S; Joint Clinical Research Centre, Mbarara Regional Centre of Excellence, Mbarara, Uganda., Nangiya J; Joint Clinical Research Centre, Research Department, Kampala, Uganda., Mumbiro V; University of Zimbabwe Clinical Research Centre, Harare., Mulenga V; Children's Hospital, University Teaching Hospital, Lusaka, Zambia., Musiime V; Joint Clinical Research Centre, Research Department, Kampala, Uganda.; Department of Paediatrics and Child Health, Makerere University, Kampala, Uganda., Monkiewicz LN; Medical Research Council Clinical Trials Unit, University College London, United Kingdom., Griffiths AL; Medical Research Council Clinical Trials Unit, University College London, United Kingdom., Bamford A; Medical Research Council Clinical Trials Unit, University College London, United Kingdom.; Infection, Immunity & Inflammation Department, UCL Great Ormond Street Institute of Child Health, London, United Kingdom., Doerholt K; Medical Research Council Clinical Trials Unit, University College London, United Kingdom.; Paediatric Infectious Diseases Unit, St George's University Hospital, London, United Kingdom., Denti P; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, South Africa., Burger DM; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands., Gibb DM; Medical Research Council Clinical Trials Unit, University College London, United Kingdom., McIlleron HM; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, South Africa.; Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa., Colbers A; Department of Pharmacy, Research Institute for Medical Innovation, Radboud University Medical Center, Nijmegen, The Netherlands.

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2023 Sep 18; Vol. 77 (6), pp. 875-882.