Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Monique Willart"'
Autor:
Jonathan Maelfait, Kenny Roose, Lars Vereecke, Conor Mc Guire, Mozes Sze, Martijn J Schuijs, Monique Willart, Lorena Itati Ibañez, Hamida Hammad, Bart N Lambrecht, Rudi Beyaert, Xavier Saelens, Geert van Loo
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005410 (2016)
A20 negatively regulates multiple inflammatory signalling pathways. We here addressed the role of A20 in club cells (also known as Clara cells) of the bronchial epithelium in their response to influenza A virus infection. Club cells provide a niche f
Externí odkaz:
https://doaj.org/article/b353388aaad34cc2808b975704730a7d
Autor:
Muriel Smet, Monique Willart, Jan-Ake Gustafsson, Ans De Beuckelaer, Johan Grooten, Thomas Naessens, Karl Vergote, Seppe Vander Beken, Lien Van Hoecke, Knut R. Steffensen, Bart N. Lambrecht
Publikováno v:
Immunity, Inflammation and Disease. 4:350-361
Introduction Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c13538b72cb7fa021f244f43c734c2e8
https://doi.org/10.1002/iid3.118
https://doi.org/10.1002/iid3.118
Autor:
Hamida Hammad, Sofie Vandevyver, F. Van Hauwermeiren, K. De Bosscher, Karen Dendoncker, Johan Grooten, Lien Dejager, Claude Libert, Thomas Naessens, Jolien Souffriau, E. Van Wonterghem, Mieke Eggermont, Monique Willart, Marlies Ballegeer, Bart N. Lambrecht
Publikováno v:
Mucosal Immunology, 8(6), 1212-1225. Nature Publishing Group
Asthma is a heterogeneous disorder, evidenced by distinct types of inflammation resulting in different responsiveness to therapy with glucocorticoids (GCs). Tumor necrosis factor alpha (TNF alpha) is involved in asthma pathogenesis, but anti-TNF alph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66728241e4b27de4b574b731b847f24
https://doi.org/10.1038/mi.2015.12
https://doi.org/10.1038/mi.2015.12
Autor:
Hamida Hammad, Monique Willart, Kim Deswarte, Pascal Chanez, Markus J. Ege, Karl Vergote, Delphine Gras, Erika von Mutius, Geert van Loo, Rudi Beyaert, Franz Bracher, Filipe Branco Madeira, Bart N. Lambrecht, Martijn J. Schuijs
Publikováno v:
Science, 349(6252), 1106-1110. American Association for the Advancement of Science
How farming protects against allergies People who grow up on dairy farms only rarely develop asthma or allergies. This is probably because as children, they breathe air containing bacterial components, which reduce the overall reactivity of the immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f66b11159ba551616a38e955c10eab
https://doi.org/10.1126/science.aac6623
https://doi.org/10.1126/science.aac6623
Autor:
Pieter Bogaert, Kim Deswarte, Xavier Saelens, B. G. De Geest, Johan Grooten, L. Van Hoecke, Bart N. Lambrecht, A. De Beuckelaer, Kenny Roose, Monique Willart, S. De Koker, Thomas Naessens
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
SCIENTIFIC REPORTS
Scientific Reports
SCIENTIFIC REPORTS
Due to their capacity to skew T cell responses towards Th1 oriented immunity, oligonucleotides containing unmethylated CpG motifs (CpG) have emerged as interesting adjuvants for vaccination. Whereas the signalling pathways in response to CpG mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f638d46a9045c0f77bd541d9139e8bb
https://doi.org/10.1038/s41598-017-06236-6
https://doi.org/10.1038/s41598-017-06236-6
Autor:
Hamida Hammad, Melissa Dullaers, Kaat Fierens, Martijn J. Schuijs, Justine Van Moorleghem, Monique Willart, Bart N. Lambrecht
Publikováno v:
Journal of Allergy and Clinical Immunology, 140(1), 76-+. Mosby Inc.
Background Allergic asthma is a CD4 T H 2-lymphocyte driven disease characterized by airway hyperresponsiveness and eosinophilia. B cells can present antigens to CD4 T cells and produce IgE immunoglobulins that arm effector cells; however, mouse mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98eacd2deb9fffef35ff124e7edbd9f1
https://pure.eur.nl/en/publications/013cc746-0cc8-4840-8ae9-f97924229ea2
https://pure.eur.nl/en/publications/013cc746-0cc8-4840-8ae9-f97924229ea2
Autor:
Martijn J. Schuijs, Rudi Beyaert, Ismé de Kleer, Monique Willart, Mirjam Kool, Padraic G. Fallon, Justine Van Moorleghem, Hamida Hammad, Emily Hams, Maud Plantinga, Marjolein J. W. de Bruijn, Bart N. Lambrecht, Rudi W. Hendriks
Publikováno v:
Immunity, 45(6), 1285-1298. Cell Press
Allergic disease originates in early life and polymorphisms in interleukin-33 gene (IL33) and IL1RL1, coding for IL-33R and decoy receptor sST2, confer allergy risk. Early life T helper 2 (Th2) cell skewing and allergy susceptibility are often seen a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5622601e94ee8983c923c000a4d91d3d
https://pubmed.ncbi.nlm.nih.gov/28044058
https://pubmed.ncbi.nlm.nih.gov/28044058
Autor:
Monique Willart, A. J. M. Van Oosterhout, Hamida Hammad, Gesine Hansen, Tim Sparwasser, S. Shirinbak, Martijn C. Nawijn, Abdul Mannan Baru, Hadi Maazi, Bart N. Lambrecht, Louis Boon, Venkateswaran Ganesh, M. Cabanski
Publikováno v:
Clinical and Experimental Allergy, 42(10), 1519-1528. Wiley
Clinical & Experimental Allergy, 42(10), 1519-1528. Wiley-Blackwell Publishing Ltd
Clinical & Experimental Allergy, 42(10), 1519-1528. Wiley-Blackwell Publishing Ltd
Background Allergen-specific immunotherapy (SIT) has been used since 1911, yet its mechanism of action remains to be elucidated. There is evidence indicating that CD4+FOXP3+ regulatory T cells (Treg cells) are induced during SIT in allergic patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e531b5be988ba1a0eaddf101cb93775
https://doi.org/10.1111/j.1365-2222.2012.04064.x
https://doi.org/10.1111/j.1365-2222.2012.04064.x
Autor:
Jean Paul Remon, Monique Willart, Johan Grooten, Chris Vervaet, Stefaan De Koker, Xavier Saelens, Pieter Bogaert, Marina De Filette, Bart N. Lambrecht, Hamida Hammad, Charlotte Pollard, Bruno G. De Geest
Publikováno v:
ACS Nano. 6:2136-2149
Recombinant antigens hold high potential to develop vaccines against lethal intracellular pathogens and cancer. However, they are poorly immunogenic and fail to induce potent cellular immunity. In this paper, we demonstrate that polymeric multilayer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0d0323257eea22b0be7900c7040acf
https://doi.org/10.1021/nn205099c
https://doi.org/10.1021/nn205099c
Autor:
Monique Willart, Philippe Pouliot, Hamida Hammad, Bart N. Lambrecht, Rudi Beyaert, Harald Braun, Kim Deswarte
Publikováno v:
Journal of Experimental Medicine, 209(8), 1505-1517. Rockefeller University Press
The Journal of Experimental Medicine
The Journal of Experimental Medicine
IL-1α promotes a cascade of cytokine production from epithelial cells culminating in Th2 immunity to house dust mite allergens.
House dust mite (HDM) is one of the most common allergens worldwide. In this study, we have addressed the involvemen
House dust mite (HDM) is one of the most common allergens worldwide. In this study, we have addressed the involvemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a598cef43d613304c50c98d35e16ddde
https://pure.eur.nl/en/publications/ee6a87df-6bff-459f-837a-593a1589b4ab
https://pure.eur.nl/en/publications/ee6a87df-6bff-459f-837a-593a1589b4ab