Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Monique Verhaegen"'
Autor:
Richard R. Neubig, Elizabeth R. Lawlor, Monique Verhaegen, Scott D. Larsen, Melanie A. Krook, Merlin Airik, Cheryl E. Rockwell, Jessica L. Bell, Susan M. Wade, Yajing Ji, Sean A. Misek, Erika M. Lisabeth, Kathryn M. Appleton, Andrew J. Haak
To show that MRTF-A localization was dependent on F-actin dynamics, we stimulated SK-Mel-19 cells with 20% FBS to induce stress fiber formation which induced MRTF-A nuclear localization. We also treated SK-Mel-147 cells with latrunculin B which inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1117c9e2a1495f7253941a73c0d5452d
https://doi.org/10.1158/1535-7163.22508319
https://doi.org/10.1158/1535-7163.22508319
Autor:
Richard R. Neubig, Elizabeth R. Lawlor, Monique Verhaegen, Scott D. Larsen, Melanie A. Krook, Merlin Airik, Cheryl E. Rockwell, Jessica L. Bell, Susan M. Wade, Yajing Ji, Sean A. Misek, Erika M. Lisabeth, Kathryn M. Appleton, Andrew J. Haak
The Cancer Genome Atlas (TCGA) cutaneous melanoma dataset was stratified into quartiles based upon expression of indicated genes. Kaplan-Meier plots were generated from the highest (grey) and lowest (black) expressing quartiles. Survival curves were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412fad174ba69ff2635cf96a88d4e660
https://doi.org/10.1158/1535-7163.22508322.v1
https://doi.org/10.1158/1535-7163.22508322.v1
Autor:
María S. Soengas, Scott W. Lowe, Anthony W. Opipari, Philipp Steiner, Jenny L. Rush, Thomas P. Miller, Monique Verhaegen, Yolanda Fernández
Supplementary Figures 1-6 from Differential Regulation of Noxa in Normal Melanocytes and Melanoma Cells by Proteasome Inhibition: Therapeutic Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e20a6c029aa98acfe3bb34be197c99
https://doi.org/10.1158/0008-5472.22363731.v1
https://doi.org/10.1158/0008-5472.22363731.v1
Autor:
María S. Soengas, Scott W. Lowe, Anthony W. Opipari, Philipp Steiner, Jenny L. Rush, Thomas P. Miller, Monique Verhaegen, Yolanda Fernández
Melanoma is the most aggressive form of skin cancer and advanced stages are invariably resistant to conventional therapeutic agents. Using bortezomib as a prototypic proteasome inhibitor, we have identified a novel and critical role of the proteasome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5185bd36acd00e2f9bc9c982dc96a617
https://doi.org/10.1158/0008-5472.c.6493857.v1
https://doi.org/10.1158/0008-5472.c.6493857.v1
Constitutive activation of the mitogen-activated protein kinase (MAPK) pathway is implicated in the development and progression of many human cancers, including melanoma. Mutually exclusive activating mutations in NRAS or BRAF have been identified in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64cb1ccd3a6d0f61564e6c8c9f38ddb8
https://doi.org/10.1158/0008-5472.c.6499695.v1
https://doi.org/10.1158/0008-5472.c.6499695.v1
Autor:
María S. Soengas, Shaomeng Wang, Carol R. Bradford, Thomas E. Carey, Matt Van Brocklin, James T. Elder, Rajan Nair, Audrey Bengtson, Zaneta Nikolovska-Coleska, J. Chadwick Brenner, Keith G. Wolter, Guoping Wang, Cristina Martín de la Vega, Joshua A. Bauer, Monique Verhaegen
Supplementary Figures 1-5 from A Novel BH3 Mimetic Reveals a Mitogen-Activated Protein Kinase–Dependent Mechanism of Melanoma Cell Death Controlled by p53 and Reactive Oxygen Species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65bb6e82596a38c226aef142a000a5c7
https://doi.org/10.1158/0008-5472.22367103.v1
https://doi.org/10.1158/0008-5472.22367103.v1
Autor:
María S. Soengas, Shaomeng Wang, Carol R. Bradford, Thomas E. Carey, Matt Van Brocklin, James T. Elder, Rajan Nair, Audrey Bengtson, Zaneta Nikolovska-Coleska, J. Chadwick Brenner, Keith G. Wolter, Guoping Wang, Cristina Martín de la Vega, Joshua A. Bauer, Monique Verhaegen
The RAS/BRAF/MEK/ERK mitogen-activated protein kinase (MAPK) pathway is emerging as a key modulator of melanoma initiation and progression. However, a variety of clinical studies indicate that inhibiting the MAPK pathway is insufficient per se to eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c4c60b75f19831beb1a6d18659d6f0
https://doi.org/10.1158/0008-5472.c.6495426
https://doi.org/10.1158/0008-5472.c.6495426
Autor:
María S. Soengas, Scott W. Lowe, Anthony W. Opipari, Philipp Steiner, Jenny L. Rush, Thomas P. Miller, Monique Verhaegen, Yolanda Fernández
Supplementary Information from Differential Regulation of Noxa in Normal Melanocytes and Melanoma Cells by Proteasome Inhibition: Therapeutic Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9eb42a360b013e62024458ed7b388d
https://doi.org/10.1158/0008-5472.22363728.v1
https://doi.org/10.1158/0008-5472.22363728.v1
Autor:
María S. Soengas, Shaomeng Wang, Carol R. Bradford, Thomas E. Carey, Matt Van Brocklin, James T. Elder, Rajan Nair, Audrey Bengtson, Zaneta Nikolovska-Coleska, J. Chadwick Brenner, Keith G. Wolter, Guoping Wang, Cristina Martín de la Vega, Joshua A. Bauer, Monique Verhaegen
Supplementary Materials, Methods and Figure Legends 1-5 from A Novel BH3 Mimetic Reveals a Mitogen-Activated Protein Kinase–Dependent Mechanism of Melanoma Cell Death Controlled by p53 and Reactive Oxygen Species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2272495c178f08c83ca6edf04e6072cd
https://doi.org/10.1158/0008-5472.22367100
https://doi.org/10.1158/0008-5472.22367100