Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Monique Semichon"'
Autor:
Laura Inés Salazar-Fontana, Sophie Faure, Jérôme Delon, Ronald N. Germain, Georges Bismuth, Victor L. J. Tybulewicz, Monique Semichon, Alain Trautmann
Publikováno v:
Nature Immunology. 5:272-279
During activation, T cells associate with antigen-presenting cells, a dynamic process that involves the formation of a broad area of intimate membrane contact known as the immunological synapse. The molecular intermediates that link initial antigen r
Autor:
Christine Denoyelle, Nicolas Cagnard, Vladimir Lazar, Anne Dubart-Kupperschmitt, Georges Bismuth, Stéphanie Fabre, Florent Carrette, David A. Fruman, Marianne Mangeney, Valérie Lang, Jing Chen, Monique Semichon
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 181 (5), pp.2980-9
Journal of Immunology, 2008, 181 (5), pp.2980-9
Scopus-Elsevier
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 181 (5), pp.2980-9
Journal of Immunology, 2008, 181 (5), pp.2980-9
Scopus-Elsevier
In T cells, the PI3K pathway promotes proliferation and survival induced by Ag or growth factors, in part by inactivating the FOXO transcription factor 1. We now report that FOXO1 controls the expression of L-selectin, an essential homing molecule, i
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 170(9)
Physiologically, Ag detection by T cells occurs at the immunological synapse (IS) formed at the interface with an APC. CD5 is considered as an inhibitory molecule for Ag receptor-mediated signals in T cells. However, the influence of CD5 at the IS on
Publikováno v:
European journal of immunology. 27(12)
Sam68 has been initially described as a substrate of src kinases during mitosis in fibroblasts. Recent evidence suggests that in T lymphocytes Sam68 may act as an adaptor protein and participate in the early biochemical cascade triggered after CD3 st
Autor:
Hélène Merle-Béral, Florence Cymbalista, Monique Semichon, Michel Ticchioni, Frederic Davi, Rémi Letestu, Magali Le Garff-Tavernier, Martine Brissard, Françoise Vuillier
Publikováno v:
Blood. 104:4771-4771
Background : Expression of ZAP-70 protein has been shown to be correlated with mutational status of immunoglobulin heavy-chain variable region (IgVH) genes, a major prognostic factor in CLL. We investigated whether the detection of ZAP-70 protein by