Výsledky vyhledávání - "Monique Saunier"

Use of bispectral index to monitor the depth of sedation in mechanically ventilated patients in the prehospital setting

Autor: Sonja Curac, Monique Saunier, Jean Mantz, Tobias Gauss, Béatrice Larroque, Julien Josseaume, François-Xavier Duchateau, Estelle Wojciechowski-Bonnal

Publikováno v: Emergency Medicine Journal. 31:669-672

Sedative drug administration is a challenging aspect of the management of mechanically ventilated patients in the out-of-hospital critical care medicine. We hypothesised that the bispectral index of the EEG (BIS) could be a helpful tool in evaluating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90588369dd13eab4e64310a24f089245
https://doi.org/10.1136/emermed-2012-202238

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Purification by cobalamin-Sepharose affinity chromatography and intrinsic factor-binding activity of an extramembrane proteolytic product from pig ileal mucosa

Autor: Jean-Louis Guéant, Amal Safi, Monique Saunier, Jean-Claude Michalski, Isabelle Gastin, Alibada Yerima

Publikováno v: Biochemical Journal. 313:675-681

We have purified a cobalamin-binding protein obtained by papain digestion of pig intestine by cobalamin-AH-Sepharose affinity chromatography, with a purification factor of 17300, a yield of 63% and a cobalamin-binding activity of 11260 pmol/mg of pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7784a5831d9419aeff62f80a211170
https://doi.org/10.1042/bj3130675

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Decreased activity of intestinal and urinary intrinsic factor in Gräsbeck-Imerslund disease

Autor: Bernard Duclos, Jean-Louis Guéant, Isabelle Gastin, Ralph Gräsbeck, Marc André Bigard, Amal Safi, Thierry Lamireau, Monique Saunier

Publikováno v: Gastroenterology. 108:1622-1628

Background/Aims: The pathogenesis of inherited intestinal cobalamin malabsorption (Grasbeck-Imerslund disease) remains unknown. The authors studied whether the disease corresponds to a defective expression and/or function of the intrinsic factor-coba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec1aa335722a59cd2b4234b932b52574
https://doi.org/10.1016/0016-5085(95)90122-1

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Activities of extracts from saponin-containing plants on sheep erythrocytes, Tetrahymena pyriformis and Rumen protozoa

Autor: David Guilet, Pierre Chicoteau, Monique Saunier, Alexandre Budan, M. Wident, Denis Bellenot, Pascal Richomme

Publikováno v: International Congress on Natural Products Research on Global Change, Natural Products and Human Health/8th Joint Meeting of AFERP, ASP, GA, PSE and SIF
International Congress on Natural Products Research on Global Change, Natural Products and Human Health/8th Joint Meeting of AFERP, ASP, GA, PSE and SIF, 2012, New-York, United States. Planta Medica, 78 (11), 2012, ⟨10.1055/s-0032-1321063⟩

International audience; As the effects of saponins in the rumen are due to their membrane-disrupting ability on protozoa, the activities of extracts from saponin containing plants were determined on erythrocytes, Tetrahymena pyriformis and rumen prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f912edfc128ec13100d2442d1a3023
https://doi.org/10.1055/s-0032-1321063

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Intrinsic factor receptor during fetal development of the human intestine

Autor: H. Schohn, Monique Saunier, Jean-Louis Guéant, B. Leheup, G. Grignon, Jean-Pierre Nicolas

Publikováno v: Biochemical Journal. 286:153-156

Intrinsic factor receptor activity was observed in mucosal homogenates from whole small intestine and colon of 10-19-week fetuses, whereas it was only detected in the distal part of the small intestine of a 25-week fetus. The receptor-intrinsic facto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a483ac5cf5b65bf96029c612fe4d78
https://doi.org/10.1042/bj2860153

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Receptor-mediated endocytosis of the intrinsic factor-cobalamin complex in HT 29, a human colon carcinoma cell line

Autor: Jean-Louis Guéant, M. Girr, C. Masson, H. Schohn, Monique Saunier, Jean-Pierre Nicolas

Publikováno v: FEBS Letters. 297:229-232

A HT 29 cell line derived from human colonic carcinoma was shown to express the intrinsic factor receptor, with about 5000 binding sites per cell and an association constant of 20 x 10(9) 1/mol at pH 7.4 and 4 degrees C. The number of binding sites i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5747cef3e3421da8df5d55b6140f248
https://doi.org/10.1016/0014-5793(92)80544-q

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Binding assay and physicochemical characteristics of solubilized intrinsic factor receptor in ileal mucosal homogenates using phenyl-Sepharose to separate the saturated receptor from free intrinsic factor

Autor: H. Brulé, Jean-Louis Guéant, H. Schohn, Jean-Pierre Nicolas, Ralph Gräsbeck, Monique Saunier

Publikováno v: Biochimica et Biophysica Acta (BBA) - General Subjects. 1073:614-618

A radioisotopic assay was set to determine the physicochemical properties of the solubilized intrinsic factor receptor in pig mucosal extracts. In this assay, phenyl-Sepharose was used to separate the receptor-intrinsic factor-labelled cobalamin comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed4c47a254c17367a2a6269873ab302
https://doi.org/10.1016/0304-4165(91)90238-c

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Neurosphere-derived neural cells show region-specific behaviour in vitro

Autor: Chantal Ripoll, Jean-Philippe Hugnot, Lionel Simonneau, Monique Saunier, Sylvain Armando, Aurore Lebrun

Publikováno v: Neuroreport. 18(15)

Neurosphere cultures provide a useful model to study neural stem/progenitor cells (NSC/NPCs). The degree to which neurospheres (NS) retain their regional identity in vitro has, however, been questioned. Here, NS obtained from mouse embryonic cortex,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80639514e750c265f1f7e784f1391e2
https://pubmed.ncbi.nlm.nih.gov/17885597

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Exogenous and fibroblast growth factor 2/epidermal growth factor-regulated endogenous cytokines regulate neural precursor cell growth and differentiation

Autor: Vanessa Fritz, Alain Privat, Christophe Tran Van Ba, Cecile Dromard, Jean-Philippe Hugnot, Jean-Charles Sabourin, Loic P. Deleyrolle, Monique Saunier, Sophie Marchal-Victorion

Publikováno v: Stem cells (Dayton, Ohio). 24(3)

Neurospheres (NSs) are clonal cellular aggregates composed of neural stem cells and progenitors. A comprehensive description of their proliferation and differentiation regulation is an essential prerequisite for their use in biotherapies. Cytokines a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a8765f52da896d82ca3be93d6a7466
https://pubmed.ncbi.nlm.nih.gov/16166253

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