Apple procyanidins decrease cholesterol esterification and lipoprotein secretion in Caco-2/TC7 enterocytes

Autor: Romain Vidal, Sandra Hernandez-Vallejo, Thomas Pauquai, Odile Texier, Monique Rousset, Jean Chambaz, Sylvie Demignot, Jean-Marc Lacorte

Publikováno v: Journal of Lipid Research, Vol 46, Iss 2, Pp 258-268 (2005)

Decrease of plasma lipid levels by polyphenols was linked to impairment of hepatic lipoprotein secretion. However, the intestine is the first epithelium that faces dietary compounds, and it contributes to lipid homeostasis by secreting triglyceride-r

Externí odkaz: https://doaj.org/article/f669b0fbe7b34781bf664956f7567826

Sensing of dietary lipids by enterocytes: a new role for SR-BI/CLA-1.

Autor: Olivier Béaslas, Carine Cueille, François Delers, Danielle Chateau, Jean Chambaz, Monique Rousset, Véronique Carrière

Publikováno v: PLoS ONE, Vol 4, Iss 1, p e4278 (2009)

BACKGROUND: The intestine is responsible for absorbing dietary lipids and delivering them to the organism as triglyceride-rich lipoproteins (TRL). It is important to determine how this process is regulated in enterocytes, the absorptive cells of the

Externí odkaz: https://doaj.org/article/4e103f2371e04384866cbcae8327531c

The cellular prion protein PrP(c) is involved in the proliferation of epithelial cells and in the distribution of junction-associated proteins.

Autor: Etienne Morel, Stéphane Fouquet, Carine Strup-Perrot, Cathy Pichol Thievend, Constance Petit, Damarys Loew, Anne-Marie Faussat, Lucile Yvernault, Martine Pinçon-Raymond, Jean Chambaz, Monique Rousset, Sophie Thenet, Caroline Clair

Publikováno v: PLoS ONE, Vol 3, Iss 8, p e3000 (2008)

BACKGROUND: The physiological function of the ubiquitous cellular prion protein, PrP(c), is still under debate. It was essentially studied in nervous system, but poorly investigated in epithelial cells. We previously reported that PrP(c) is targeted

Externí odkaz: https://doaj.org/article/aee078e6e9b748c8aec06d84aa1a3193

Short Term Palmitate Supply Impairs Intestinal Insulin Signaling via Ceramide Production

Autor: Armelle Leturque, Agnieszka Blachnio-Zabielska, Véronique Carrière, Sylvie Demignot, Eric Hajduch, Jean-Paul Pais de Barros, Pascal Ferré, Bárbara Graziela Postal, Agnès Ribeiro, Céline Osinski, Monique Rousset, Thi Thu Trang Tran

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (31), pp.16328-16338. 〈10.1074/jbc.M115.709626〉
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (31), pp.16328-16338. ⟨10.1074/jbc.M115.709626⟩
Journal of Biological Chemistry, 2016, 291 (31), pp.16328-16338. ⟨10.1074/jbc.M115.709626⟩

International audience; The worldwide prevalence of metabolic diseases is increasing, and there are global recommendations to limit consumption of certain nutrients, especially saturated lipids. Insulin resistance, a common trait occurring in obesity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16b94c3669790f4d644cbf832e39cd98
https://doi.org/10.1074/jbc.m115.709626

Glucose Tolerance Is Improved in Mice Invalidated for the Nuclear Receptor HNF-4γ: A Critical Role for Enteroendocrine Cell Lineage

Autor: Ghislaine Guillemain, Monique Rousset, Michel Lacasa, Philippe Cardot, Patricia Serradas, Floriane Baraille, Agnès Ribeiro, Céline Osinski, B. Blondeau, Véronique Carrière, Kevin Garbin, Sami Ayari

Publikováno v: Diabetes. 64:2744-2756

Intestine contributes to energy homeostasis through the absorption, metabolism, and transfer of nutrients to the organism. We demonstrated previously that hepatocyte nuclear receptor-4α (HNF-4α) controls intestinal epithelium homeostasis and intest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78ba596c16c8598eb0ecca502d057f5
https://doi.org/10.2337/db14-0993