Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Monique Rijnkels"'
Autor:
Steven W. Wall, Lilia Sanchez, Kelly Scribner Tuttle, Scott J. Pearson, Shivatheja Soma, Garhett L. Wyatt, Hannah N. Carter, Ramsey M. Jenschke, Lin Tan, Sara A. Martinez, Philip L. Lorenzi, Vishal M. Gohil, Monique Rijnkels, Weston W. Porter
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 5, Pp 1046-1063 (2023)
Abstract Dysregulation of cellular metabolism is a hallmark of breast cancer progression and is associated with metastasis and therapeutic resistance. Here, we show that the breast tumor suppressor gene SIM2 promotes mitochondrial oxidative phosphory
Externí odkaz:
https://doaj.org/article/053db100e0644f5393e7cef5cb54595e
Autor:
Scott J. Pearson, Jessica Elswood, Rola Barhoumi, Brittini Ming-Whitfield, Monique Rijnkels, Weston W. Porter
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-14 (2019)
Abstract Background Mutations in genes associated with homologous recombination (HR) increase an individual’s risk of developing triple-negative breast cancer (TNBC). Although known for their role in repairing dsDNA breaks, HR repair elements also
Externí odkaz:
https://doaj.org/article/1fd0c61af2304bf5b0389420b309c047
Autor:
Xin Fang, Nan Ni, Xiaofang Wang, Yanan Tian, Ivan Ivanov, Monique Rijnkels, Kayla J. Bayless, John P. Lydon, Qinglei Li
Publikováno v:
Cells, Vol 11, Iss 5, p 909 (2022)
Enhancer of zeste homolog 2 (EZH2), a core component of polycomb repressive complex 2, plays an important role in cancer development. As both oncogenic and tumor suppressive functions of EZH2 have been documented in the literature, the objective of t
Externí odkaz:
https://doaj.org/article/414fcc2f32924f1bb4e0ecd8014c1061
Autor:
Monique Rijnkels, Courtneay Freeman-Zadrowski, Joseph Hernandez, Vani Potluri, Liguo Wang, Wei Li, Danielle G Lemay
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53270 (2013)
Unlike other tissues, development and differentiation of the mammary gland occur mostly after birth. The roles of systemic hormones and local growth factors important for this development and functional differentiation are well-studied. In other tiss
Externí odkaz:
https://doaj.org/article/d574b2551bcb4103b2a865fa92c51fd6
Autor:
Danielle G Lemay, Katherine S Pollard, William F Martin, Courtneay Freeman Zadrowski, Joseph Hernandez, Ian Korf, J Bruce German, Monique Rijnkels
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75030 (2013)
Even in genomes lacking operons, a gene's position in the genome influences its potential for expression. The mechanisms by which adjacent genes are co-expressed are still not completely understood. Using lactation and the mammary gland as a model sy
Externí odkaz:
https://doaj.org/article/dbb36288d2934c8bac4ef94d42fbb2e2
Autor:
Lilia Sanchez, Jessica Epps, Steven Wall, Cole McQueen, Scott J. Pearson, Kelly Scribner, Elizabeth A. Wellberg, Erin D. Giles, Monique Rijnkels, Weston W. Porter
Publikováno v:
Cell Death & Differentiation.
The functionally differentiated mammary gland adapts to extreme levels of stress from increased demand for energy by activating specific protective mechanisms to support neonatal health. Here, we identify the breast tumor suppressor gene, single-mind
Autor:
Hamid Beiki, Brenda M. Murdoch, Carissa A. Park, Chandlar Kern, Denise Kontechy, Gabrielle Becker, Gonzalo Rincon, Honglin Jiang, Huaijun Zhou, Jacob Thorne, James E. Koltes, Jennifer J. Michal, Kimberly Davenport, Monique Rijnkels, Pablo J. Ross, Rui Hu, Sarah Corum, Stephanie McKay, Timothy P.L. Smith, Wansheng Liu, Wenzhi Ma, Xiaohui Zhang, Xiaoqing Xu, Xuelei Han, Zhihua Jiang, Zhi-Liang Hu, James M. Reecy
Functional annotation of the bovine genome was performed by characterizing the spectrum of RNA transcription using a multi-omics approach, combining long- and short-read transcript sequencing and orthogonal data to identify promoters and enhancers an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7b4747156cf34b38d37814a2f818a39
https://doi.org/10.1101/2022.10.05.510963
https://doi.org/10.1101/2022.10.05.510963
Autor:
Monique Rijnkels, Weston Porter, Scott J. Pearson, Jessica Elswood, Rola Barhoumi, H. Ross Payne
Publikováno v:
Autophagy
Mitochondria operate as a central hub for many metabolic processes by sensing and responding to the cellular environment. Developmental cues from the environment have been implicated in selective autophagy, or mitophagy, of mitochondria during cell d
Autor:
Monique Rijnkels, Scott J. Pearson, Jessica Elswood, Weston Porter, Rola Barhoumi, Brittini Ming-Whitfield
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-14 (2019)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Background Mutations in genes associated with homologous recombination (HR) increase an individual’s risk of developing triple-negative breast cancer (TNBC). Although known for their role in repairing dsDNA breaks, HR repair elements also stabilize
Publikováno v:
Am J Pathol
Normal proliferation and differentiation of uterine epithelial cells are critical for uterine development and function. Enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2), a core component of polycomb repressive complexes 2, possesses h