Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Monique Murawsky"'
Publikováno v:
Brain Research. 930:53-57
The wobbler mutant mouse displays a recessively inherited neurological disease with degeneration of motoneurons and is considered to be an animal model for human motoneuron diseases. Mutant mice can be clinically recognised at about 3-4 weeks of age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00ca3aa7cf4e95895afa43ac81bd572
https://doi.org/10.1016/s0006-8993(01)03405-9
https://doi.org/10.1016/s0006-8993(01)03405-9
Publikováno v:
Neuroscience Letters. 305:202-206
In neurodegenerative diseases, such as Alzheimer's disease or HIV encephalitis, neuronal DNA fragmentation has been observed at unexpected high frequencies, without definitive evidence for activation of an irreversible apoptotic pathway. The wobbler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea15459d7c6522bacf914d7f982f348
https://doi.org/10.1016/s0304-3940(01)01741-4
https://doi.org/10.1016/s0304-3940(01)01741-4
Autor:
A. Aït-Ikhlef, Monique Murawsky, François Rieger, Brigitte Blondet, Qiao Yan, Linxi Li, Lucien J. Houenou
Publikováno v:
Journal of the Neurological Sciences. 153:20-24
Several new neurotrophic factors have been recently identified and shown to prevent motoneuron death in vitro and in vivo. One such agent is brain-derived neurotrophic factor (BDNF). In this study, we tested BDNF on an animal model of early-onset mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5e991dbbe966bf40344bbabca046f4
https://doi.org/10.1016/s0022-510x(97)00171-8
https://doi.org/10.1016/s0022-510x(97)00171-8
Autor:
Monique Murawsky, François Rieger, A. Aït-Ikhlef, Brigitte Blondet, J.C. Martinou, D. Hantaz-Ambroise
Publikováno v:
Neuroscience Letters. 199:163-166
The wobbler mouse mutation, an autosomal recessive mutation, leads to motoneuron degeneration in early post-natal development. Transgenic mice in which neurons overexpress human bcl2 transgene have been generated: the overexpression of bcl2 reduces t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6137c2ee75e4a53f36cd632f8e006ecb
https://doi.org/10.1016/0304-3940(95)12061-8
https://doi.org/10.1016/0304-3940(95)12061-8
Autor:
C. Lagord, J.L. Vaught, Mohammed Akaaboune, François Rieger, Brigitte Blondet, Lucien J. Houenou, Monique Murawsky, Daniel Hantaï, Barry W. Festoff
Publikováno v:
Journal of the Neurological Sciences. 129:122-126
Recombinant human insulin-like growth factor-I (IGF-I) is being considered as a possible therapeutic agent for the treatment of motoneuron diseases like amyotrophic lateral sclerosis. The neurological mutant mouse wobbler, carries an autosomal recess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac154637e18cd9a84c26314270c7a5dc
https://doi.org/10.1016/0022-510x(95)00081-c
https://doi.org/10.1016/0022-510x(95)00081-c
Autor:
Monique Murawsky, Brigitte Blondet, D. Hantaz-Ambroise, François Rieger, A. Aït-Ikhlef, Danièle Cambier
Publikováno v:
Neuroscience Letters. 183:179-182
Mice affected by the wobbler mutation are characterized by a muscular atrophy associated with motoneuron degeneration. As soon as the first clinical signs of the disease appear, reactive astrocytes, strongly glial fibrillary acidic protein (GFAP)-pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280e12879273059416012c65bffbb164
https://doi.org/10.1016/0304-3940(94)11145-9
https://doi.org/10.1016/0304-3940(94)11145-9
Publikováno v:
Developmental Biology. 149:381-394
The expression of cytotactin, an extracellular matrix glycoprotein involved in morphogenesis and regeneration, was determined in the normal and regenerating neuromuscular system of the frog Rana temporaria. Cytotactin was expressed in adult brain and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bcbea17bbf18559082eb8a17ca0ba3
https://doi.org/10.1016/0012-1606(92)90293-p
https://doi.org/10.1016/0012-1606(92)90293-p
Publikováno v:
Journal of neurocytology. 23(3)
The wobbler mutation is inherited as an autosomal recessive trait and displays a muscular atrophy associated with motoneuron degeneration in early postnatal development. It has been shown that the level of glial fibrillary acidic protein (GFAP) is gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375c5fd20302665a5dd4a1308b722f9d
https://pubmed.ncbi.nlm.nih.gov/8006678
https://pubmed.ncbi.nlm.nih.gov/8006678
Autor:
Martine Pinçon-Raymond, Monique Murawsky, Marc Nicolet, François Rieger, Giovanni Levi, Gerald M. Edelman
Publikováno v:
The Journal of Cell Biology
The neural cell adhesion molecule (N-CAM) is a membrane glycoprotein involved in neuron-neuron and neuron-muscle adhesion. It can be synthesized in various forms by both nerve and muscle and it becomes concentrated at the motor endplate. Biochemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88e3f5c2ab4e43ec1a3be63f4f9dec9
https://doi.org/10.1083/jcb.107.2.707
https://doi.org/10.1083/jcb.107.2.707
Publikováno v:
Developmental Biology. 124:259-268
In the muscular dysgenic ( mdg mdg ) mouse embryo, both muscle and nerve are affected early during embryogenesis, from Embryonic Day 13 (E13). We now find that the mutation affects not only the degree of differentiation of the muscle and the pattern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65348a3444860d39a7740c1a244036d7
https://doi.org/10.1016/0012-1606(87)90477-5
https://doi.org/10.1016/0012-1606(87)90477-5