Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Monique Monnot"'
Publikováno v:
Journal of Biological Chemistry. 270:17502-17507
Results are presented on a peptide fragment (1013-1056) from human DNA topoisomerase II alpha. This was selected using the procedure of Lupas et al. (Lupas, A., Van Dyke, M., and Stock, J. (1991) Science 252, 1162-1164) for its potential to adopt a s
Autor:
Odile Convert, Serge Fermandjian, Olivier Mauffret, Said El Antri, Patrick Bittoun, Monique Monnot, Elie Lescot
Publikováno v:
Biochemistry. 32:7079-7088
We examined the structural properties of six octanucleotide duplexes d(TGACGTCA), d(ACTGCAGT), d(CTTCGAAG), d(CATCGATG), d(GTACGTAC), and d(CATGCATG). Circular dichroism (CD) and 2D 31P and 1H NMR spectroscopies were used in conjunction. Although of
Publikováno v:
European Journal of Biochemistry. 204:1035-1039
Circular dichroism was applied to the analysis of drug-DNA associations. With the octanucleotide d(TGACGTCA) (octanucleotide I), which is the cAMP-responsive element (CRE) in gene promoters and its reverse d(ACTGCAGT) (octanucleotide II), it was demo
Autor:
Bernard Psaume, Serge Fermandjian, Monique Monnot, Jean Belehradek, Elie Lescot, Olivier Mauffret, Jean-Marie Saucier, Valérie Simon
Publikováno v:
FEBS Letters. 273:71-74
UV-absorption and circular dichroism (CD) experiments showed that ellipticine derivatives may interact with DNA according to 3 possible binding modes depending on their structure and concentration. The first mode concerned intercalation of 1-methyl-9
Publikováno v:
Electrophoresis
Electrophoresis, Wiley-VCH Verlag, 2002, 23 (7-8), pp.1013-20. ⟨10.1002/1522-2683(200204)23:7/83.0.CO;2-B⟩
Electrophoresis, Wiley-VCH Verlag, 2002, 23 (7-8), pp.1013-20. ⟨10.1002/1522-2683(200204)23:7/83.0.CO;2-B⟩
International audience; In order to identify possible signatures of the most typical structures adopted by guanine-rich oligonucleotides, we submitted them to the crossed fire of circular dichroism (CD) and electrophoresis. These signatures show up i
A DNA hairpin with a single residue loop closed by a strongly distorted Watson-Crick G x C base-pair
Autor:
C. El Amri, Serge Fermandjian, Olivier Mauffret, G. Tevanian, Horea Porumb, Elie Lescot, Monique Monnot
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 1999, 294 (2), pp.427-42. ⟨10.1006/jmbi.1999.3270⟩
Journal of Molecular Biology, Elsevier, 1999, 294 (2), pp.427-42. ⟨10.1006/jmbi.1999.3270⟩
International audience; Our previous NMR and modeling studies have shown that the single-stranded 19mer oligonucleotides d(AGCTTATC-ATC-GATAA GCT) -ATC- and d(AGCTTATC-GAT-GATAAGCT) -GAT- encompassing the strongest topoisomerase II cleavage site in p
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 1999, 27 (24), pp.4759-67
Nucleic Acids Research, Oxford University Press, 1999, 27 (24), pp.4759-67
International audience; In a previous NMR study we detected the presence of particular motions and hydration properties within the DNA fragment d(CTACTGCTTTAG).d(CTAAAGCAGTAG). Now, we report on an NMR and molecular modelling analysis of this sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c04a422380f03537bf46fa405f67fe
https://hal.archives-ouvertes.fr/hal-00284930
https://hal.archives-ouvertes.fr/hal-00284930
Autor:
Arsia Amir-Aslani, Serge Fermandjian, Elie Lescot, Monique Monnot, Richard G. Maroun, Olivier Mauffret
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 1998, 283 (3), pp.643-55. ⟨10.1006/jmbi.1998.2095⟩
Journal of Molecular Biology, Elsevier, 1998, 283 (3), pp.643-55. ⟨10.1006/jmbi.1998.2095⟩
International audience; The structural analysis of two single-stranded DNAs d(AGCTTATCATCGATAAGCT) (ATC-19) and d(AGCTTATCGATGATAAGCT) (GAT-19) was performed by NMR and restrained molecular dynamics. These oligonucleotides reproduce the 15-33 segment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678024145cc2cf946d05ee6b15304f24
https://hal.archives-ouvertes.fr/hal-00284934
https://hal.archives-ouvertes.fr/hal-00284934
Transcription factors are modular entities built up of discrete domains, some devoted to DNA binding and others permitting transcriptional modulation. The structure of DNA binding domains has been thoroughly investigated and structural classes clearl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec88529dfc82de374e4810cf3188ee8e
https://europepmc.org/articles/PMC147095/
https://europepmc.org/articles/PMC147095/
Publikováno v:
Nucleic acids research. 23(19)
In our previous works we have shown that the oligonucleotides 5'-GGGGAGGGGGAGG-3' and 5'-GGAGGGGGAGGGG-3' give very stable and specific triplexes with their target double stranded DNAs [Svinarchuk, F., Bertrand, J.-R. and Malvy, C. (1994) Nucleic Aci