Hepatoma Derived Growth Factor Enhances Oligodendrocyte Genesis from Subventricular Zone Precursor Cells

Autor: Yutong Li, Nicole Leanne Dittmann, Adrianne Eve Scovil Watson, Monique Marylin Alves de Almeida, Tim Footz, Anastassia Voronova

Publikováno v: ASN Neuro, Vol 14 (2022)

Oligodendrocytes, the myelinating cells of the central nervous system (CNS), perform vital functions in neural protection and communication, as well as cognition. Enhanced production of oligodendrocytes has been identified as a therapeutic approach f

Externí odkaz: https://doaj.org/article/cdc38c2d6d964b4aa2a3a3489bc4b715

Amburana cearensis: Pharmacological and Neuroprotective Effects of Its Compounds

Autor: Juliana Helena Castro e Silva, Rafael Short Ferreira, Erica Patricia Pereira, Suzana Braga-de-Souza, Monique Marylin Alves de Almeida, Cleonice Creusa dos Santos, Arthur Morgan Butt, Elisabetta Caiazzo, Raffaele Capasso, Victor Diogenes Amaral da Silva, Silvia Lima Costa

Publikováno v: Molecules, Vol 25, Iss 15, p 3394 (2020)

Amburana cearensis A.C. Smith is an endemic tree from Northeastern Brazil used in folk medicine as teas, decocts and syrups for the treatment of various respiratory and inflammatory diseases, since therapeutic properties have been attributed to compo

Externí odkaz: https://doaj.org/article/8aeb49701fbb4d9db9098072bb1b212c

Amburana cearensis seed extract stimulates astrocyte glutamate homeostatic mechanisms in hippocampal brain slices and protects oligodendrocytes against ischemia

Autor: Rafael Short Ferreira, Paulo Roberto Ribeiro, Juliana Helena Castro e Silva, Juliana Bender Hoppe, Monique Marylin Alves de Almeida, Beatriz Correia de Lima Ferreira, Gustavo Borges Andrade, Suzana Braga de Souza, Luzimar Gonzaga Ferdandez, Maria de Fátima Dias Costa, Christianne Gazzana Salbego, Andrea Domenico Rivera, Aline Longoni, Adriano Martimbianco de Assis, Francesca Pieropan, José Cláudio Fonseca Moreira, Silvia Lima Costa, Arthur Morgan Butt, Victor Diogenes Amaral da Silva

Background Stroke is a leading cause of death and disability worldwide. A major factor in brain damage following ischemia is excitotoxicity caused by elevated levels of the neurotransmitter glutamate. In the brain, glutamate homeostasis is a primary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510889885cd5c1c36fe3f30a072d3a5a
https://doi.org/10.21203/rs.3.rs-2109136/v1

The flavonoid agathisflavone modulates the microglial neuroinflammatory response and enhances remyelination

Autor: Manoelito Coelho dos Santos Junior, Francesca Pieropan, Arthur M. Butt, Juceni P. David, Larissa de Mattos Oliveira, Cleide dos Santos Souza, Victor Diogenes Amaral da Silva, Monique Marylin Alves de Almeida, Jorge Mauricio David, Silvia Lima Costa

Publikováno v: Almeida, M M A D, Pieropan, F, de Mattos Oliveira, L, dos Santos Junior, M C, David, J M, David, J P, da Silva, V D A, dos Santos Souza, C, Lima Costa, S & Butt, A 2020, ' The flavonoid agathisflavone modulates the microglial neuroinflammatory response and enhances remyelination ', Pharmacological Research, vol. 159, 104997 . https://doi.org/10.1016/j.phrs.2020.104997
Pharmacological Research

Graphical abstract
Highlights • Agathisflavone enhances remyelination through modulating neuroinflammation. • Agathisflavone induces a polarization in microglia from an M1 to an M2-like phenotype. • Agathisflavone interacts with the nuclea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e251c838fbe8258967007b8151031770
https://researchportal.port.ac.uk/ws/files/21482002/The_flavonoid_agathisflavone_modulates.pdf

Phytoestrogen agathisflavone ameliorates neuroinflammation-induced by LPS and IL-1β and protects neurons in cocultures of glia/neurons

Autor: Cleide dos Santos Souza, Juceni P. David, Alessandra Bispo da Silva, Naiara Silva Dourado, Rafael Short Ferreira, Victor Diogenes Amaral da Silva, Arthur M. Butt, Jorge Mauricio David, Maria de Fátima Dias Costa, Monique Marylin Alves de Almeida, Silvia Lima Costa

Publikováno v: de Almeida, M M A, Souza, C D S, Dourado, N S, da Silva, A B, Ferreira, R S, David, J M, David, J P, Costa, M D F D, da Silva, V D A, Butt, A M & Costa, S L 2020, ' Phytoestrogen agathisflavone ameliorates neuroinflammation-induced by LPS and IL-1β and protects neurons in cocultures of glia/neurons ', Biomolecules, vol. 10, no. 4, 562 . https://doi.org/10.3390/biom10040562
Biomolecules
Biomolecules, Vol 10, Iss 562, p 562 (2020)
Volume 10
Issue 4

Inflammation and oxidative stress are common aspects of most neurodegenerative diseases in the central nervous system. In this context, microglia and astrocytes are central to mediating the balance between neuroprotective and neurodestructive mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d0ee6f8cff72558f704783dbceedf7
https://researchportal.port.ac.uk/portal/en/publications/phytoestrogen-agathisflavone-ameliorates-neuroinflammationinduced-by-lps-and-il1-and-protects-neurons-in-cocultures-of-glianeurons(87de353d-f476-4b78-abef-c8516523a5f9).html