Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Monique M.A. Verstegen"'
Autor:
Kimberley Ober, Floris J.M. Roos, Gilles S. van Tienderen, Kübra Köten, Annelot Klaassen, Wunan Mi, Luc J.W. van der Laan, Monique M.A. Verstegen
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102431- (2023)
Summary: Bile ducts are essential for bile transport and consist of complex branching tubular networks. Human patient-derived cholangiocyte develops a cystic rather than branching duct morphology. Here, we present a protocol to establish branching mo
Externí odkaz:
https://doaj.org/article/84a4580cad5643e5aaecc2b8f27e89c6
Autor:
Shaojun Shi, Henk P. Roest, Thierry P.P. van den Bosch, Marcel J.C. Bijvelds, Markus U. Boehnert, Jeroen de Jonge, Sven O. Dekker, Antoine A.F. de Vries, Hugo R. de Jonge, Monique M.A. Verstegen, Luc J.W. van der Laan
Publikováno v:
EBioMedicine, Vol 88, Iss , Pp 104431- (2023)
Summary: Background: Ischemia of the bile duct is a common feature in liver disease and transplantation, which represents a major cause of morbidity and mortality, especially after liver transplantation. Detailed knowledge of its pathogenesis remains
Externí odkaz:
https://doaj.org/article/fccca7c2c5564e5b9c23a18e37e160f2
Autor:
Shaojun Shi, Monique M.A. Verstegen, Henk P. Roest, Arif I. Ardisasmita, Wanlu Cao, Floris J.M. Roos, Petra E. de Ruiter, Marije Niemeijer, Qiuwei Pan, Jan N.M. IJzermans, Luc J.W. van der Laan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 541-564 (2022)
Background & Aims: Liver and bile duct diseases often are associated with extensive cell death of cholangiocytes. Necroptosis represents a common mode of programmed cell death in cholangiopathy, however, detailed mechanistic knowledge is limited owin
Externí odkaz:
https://doaj.org/article/2f4d610e4e7d4d40a0f49cbdf8749e04
Autor:
Manon de Krijger, Thijmen Visseren, Manon E. Wildenberg, Gerrit K.J. Hooijer, Monique M.A. Verstegen, Luc J.W. van der Laan, Wouter J. de Jonge, Joanne Verheij, Cyriel Y. Ponsioen
Publikováno v:
Journal of Translational Autoimmunity, Vol 3, Iss , Pp 100054- (2020)
Introduction: The co-occurrence of inflammatory bowel disease (IBD) in up to 80% of patients with primary sclerosing cholangitis (PSC) suggests a relation between the gut and the liver in patients with both PSC and IBD. One hypothesis suggests that a
Externí odkaz:
https://doaj.org/article/f51490094da7407b8520defb59c6b939
Autor:
Hedwig S. Kruitwagen, Loes A. Oosterhoff, Ingrid G.W.H. Vernooij, Ingrid M. Schrall, Monique E. van Wolferen, Farah Bannink, Camille Roesch, Lisa van Uden, Martijn R. Molenaar, J. Bernd Helms, Guy C.M. Grinwis, Monique M.A. Verstegen, Luc J.W. van der Laan, Meritxell Huch, Niels Geijsen, Robert G. Vries, Hans Clevers, Jan Rothuizen, Baukje A. Schotanus, Louis C. Penning, Bart Spee
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 822-830 (2017)
Summary: Hepatic steatosis is a highly prevalent liver disease, yet research is hampered by the lack of tractable cellular and animal models. Steatosis also occurs in cats, where it can cause severe hepatic failure. Previous studies demonstrate the p
Externí odkaz:
https://doaj.org/article/1b75311bbf3843328b88a26d9590e37a
Autor:
Gilles S. van Tienderen, Bas Groot Koerkamp, Jan N.M. IJzermans, Luc J.W. van der Laan, Monique M.A. Verstegen
Publikováno v:
Cancers, Vol 11, Iss 11, p 1706 (2019)
Primary liver cancer, consisting predominantly of hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), remains one of the most lethal malignancies worldwide. This high malignancy is related to the complex and dynamic interactions between tumo
Externí odkaz:
https://doaj.org/article/a057fb0049f54f34bbfe3cbb0687abde
Publikováno v:
Bioengineering, Vol 6, Iss 4, p 96 (2019)
Since the first in-man liver transplantation was performed by Starzl et al [...]
Externí odkaz:
https://doaj.org/article/07e9532cd0f647b6bb9d604410a4caaa
Autor:
Floris J.M. Roos, Gilles S. van Tienderen, Haoyu Wu, Ignacio Bordeu, Dina Vinke, Laura Muñoz Albarinos, Kathryn Monfils, Sabrah Niesten, Ron Smits, Jorke Willemse, Oskar Rosmark, Gunilla Westergren-Thorsson, Daniel J. Kunz, Maurice de Wit, Pim J. French, Ludovic Vallier, Jan N.M. IJzermans, Richard Bartfai, Hendrik Marks, Ben D. Simons, Martin E. van Royen, Monique M.A. Verstegen, Luc J.W. van der Laan
Publikováno v:
Cell Stem Cell, 29, 5, pp. 776-794
Cell Stem Cell, 29(5), 776-794.e13. Cell Press
Cell Stem Cell, 29, 776-794
Cell Stem Cell, 29(5), 776-794.e13. Cell Press
Cell Stem Cell, 29, 776-794
Human cholangiocyte organoids show great promise for regenerative therapies and in vitro modeling of bile duct development and diseases. However, the cystic organoids lack the branching morphology of intrahepatic bile ducts (IHBDs). Here, we report e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4a78da49405cec33445247405f73c2
Autor:
Gilles S. van Tienderen, James Conboy, Iain Muntz, Jorke Willemse, Jantine Tieleman, Kathryn Monfils, Ivo J. Schurink, Jeroen A.A. Demmers, Michail Doukas, Gijsje H. Koenderink, Luc J.W. van der Laan, Monique M.A. Verstegen
Publikováno v:
Biomaterials Advances, 146
Biomaterials Advances, 146:213289. Elsevier Ltd.
Biomaterials Advances, 146:213289. Elsevier Ltd.
Tumor initiation and progression are critically dependent on interaction of cancer cells with their cellular and extracellular microenvironment. Alterations in the composition, integrity, and mechanical properties of the extracellular matrix (ECM) di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798ce8e4500b3bb0d820f3e58075b01d
http://resolver.tudelft.nl/uuid:57a7a46f-b889-4ee4-acf1-c5910d81eee4
http://resolver.tudelft.nl/uuid:57a7a46f-b889-4ee4-acf1-c5910d81eee4
Autor:
Gilles S. van Tienderen, Ling Li, Laura Broutier, Yoshimasa Saito, Patricia Inacio, Meritxell Huch, Florin M. Selaru, Luc J.W. van der Laan, Monique M.A. Verstegen
Publikováno v:
Cancer Cell, 40(3), 226-230. Cell Press
Reliable establishment of tumor organoids is paramount to advance applications of organoid technology for personalized medicine. Here, we share our multi-center experience on initiation and tumorigenic confirmation of hepatobiliary cancer organoids.