Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Monique Laberge"'
Autor:
Carol Buettger, Pan Chen, Jane M. Vanderkooi, Ramakanth Sarabu, Bogumil Zelent, Monique Laberge, Joseph Grimsby, Franz M. Matschinsky, Stella Odili, Dorothy Zelent, Joseph Bass, Deborah Fenner, Charles A. Stanley
Publikováno v:
Biochemical Journal. 440:203-215
GK (glucokinase) is activated by glucose binding to its substrate site, is inhibited by GKRP (GK regulatory protein) and stimulated by GKAs (GK activator drugs). To explore further the mechanisms of these processes we studied pure recombinant human G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad59fd5f28248484f134f0ad96cd6825
https://doi.org/10.1042/bj20110440
https://doi.org/10.1042/bj20110440
Publikováno v:
Journal of Raman Spectroscopy. 39:1848-1858
We measured the low-wavenumber polarized resonance Raman spectra of horse heart (hhc), chicken (chc) and yeastC102T (yc) ferrocytochromes c with Soret excitation. We examined the out-of-plane (oop) deformations of the heme groups by virtue of relativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea420e486f6c2f4564de62f4c38ce802
https://doi.org/10.1002/jrs.2050
https://doi.org/10.1002/jrs.2050
Autor:
Monique Laberge, Takashi Yonetani
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1784:1146-1158
Bohr, Hasselbalch, and Krogh discovered homotropic and heterotropic allosteric behaviors of hemoglobin (Hb) in 1903/1904. A chronological description since then of selected principal models of the allosteric mechanism of Hb, such as the Adair scheme,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e3587a9a7b527d446b6e623d3ad46e
https://doi.org/10.1016/j.bbapap.2008.04.025
https://doi.org/10.1016/j.bbapap.2008.04.025
Publikováno v:
Journal of Medicinal Chemistry. 51:3081-3093
We report results of 12 ns, all-atom molecular dynamics simulation (MDS) and Poisson-Boltzmann free energy calculations (PBFE) on calmodulin (CaM) bound to two molecules of trifluoperazine (TFP) and of N-(3,3, diphenylpropyl)- N'-[1- R-(3,4-bis-butox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416bc8f64e2a211db60f73ecdd5fa2a1
https://doi.org/10.1021/jm701406e
https://doi.org/10.1021/jm701406e
Publikováno v:
Biophysical Journal. 92(5):1709-1716
A 3-ns molecular dynamics simulation in explicit solvent was performed to examine the inter- and intradomain motions of the two-domain enzyme yeast phosphoglycerate kinase without the presence of substrates. To elucidate contributions from individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f61911ef862e093b97f5ae64cb30a30
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1764:516-521
The molecular details of the mechanism of action of allosteric effectors on hemoglobin oxygen affinity are not clearly understood. The global allostery model proposed by Yonetani et al. suggests that the binding of allosteric effectors can take place
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63614e89fa5b83be5b4fd1e8f2466529
https://doi.org/10.1016/j.bbapap.2005.12.002
https://doi.org/10.1016/j.bbapap.2005.12.002
Publikováno v:
Biopolymers. 72:241-248
Resonance Raman spectroscopy is used to probe the effect of calcium depletion on the heme group of horseradish peroxidase C at pH 8. Polarized Raman spectra are recorded with an argon ion laser at eight different wavelengths to provide a sound databa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d1e66953dbb4c170e59f6ac4d79104
https://doi.org/10.1002/bip.10417
https://doi.org/10.1002/bip.10417
Publikováno v:
Langmuir. 19:146-153
The effect of trehalose on the interaction of human serum albumin (HSA) with neutral and negatively charged small unilamellar vesicles (SUVs) composed of 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC) or of mixtures of DMPC (19:1 w/w) with 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99806f191627422fa44dd415c36cd5df
https://doi.org/10.1021/la026166q
https://doi.org/10.1021/la026166q
Publikováno v:
Biochemistry. 40:9226-9237
Horseradish peroxidase C binds a wide variety of small H-donor compounds such as benzohydroxamic acid (BHA) and 2-naphthohydroxamic acid (NHA). In this work, we use the Mg(II)-mesoporphyrin prosthetic group derivative as a spectroscopic probe of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a705a29ea18820cc3f722940d66d3e
https://doi.org/10.1021/bi002938a
https://doi.org/10.1021/bi002938a
Publikováno v:
International Journal of Quantum Chemistry. 84:290-301
Horseradish peroxidase C is an oxidoreductase which catalyzes in plant roots the oxidation of a remarkably wide variety of aromatic compounds by H2O2. The recently available X-ray structures of the enzyme bound to aromatic substrates are not indicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9503882b6f00e0ff927593ff800e3e7e
https://doi.org/10.1002/qua.1334
https://doi.org/10.1002/qua.1334