Activation State of α4β1 Integrin on Sickle Red Blood Cells Is Linked to the Duffy Antigen Receptor for Chemokines (DARC) Expression

Autor: Marie-Dominique Hardy-Dessources, Monique Decastel, Jacques Elion, Wassim El Nemer, Julien Picot, Marie-Claude Durpès, Nathalie Lemonne

Publikováno v: Journal of Biological Chemistry. 286:3057-3064

In sickle cell anemia, reticulocytes express enhanced levels of α4β1 integrin that interact mainly with vascular cell adhesion molecule-1 and fibronectin, promoting vaso-occlusion. These interactions are known to be highly sensitive to the inflamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522cac7ed29aed688fead50cf7c2114f
https://doi.org/10.1074/jbc.m110.173229

Colorectal cancer in patients seen at the teaching hospitals of Guadeloupe and Martinique: discrepancies, similarities in clinicopathological features, and p53 status

Autor: Marc Lubeth, Benoit Tressières, Anne-Marie Andrea, Jacqueline Deloumeaux, Juliette Smith-ravin, Monique Decastel, Jacqueline Veronique-Baudin, Marlene Ossondo

Publikováno v: BMC Clinical Pathology
BMC Clinical Pathology, BioMed Central, 2014, 14 (1), pp.12. ⟨10.1186/1472-6890-14-12⟩
BMC Clinical Pathology, BioMed Central, 2014, 14 (1), ⟨10.1186/1472-6890-14-12⟩

International audience; BACKGROUND: In Guadeloupe and Martinique, two French Overseas Departments, colorectal cancer (CRC) has become an essential public health issue. However, little is known about CRC characteristics and the p53 status in these pop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e9a03daae92e232094963713182ed8
https://www.hal.inserm.fr/inserm-00971313

Morphological features of the human umbilical vein in normal, sickle cell trait, and sickle cell disease pregnancies

Autor: Yannick Leborgne-Samuel, Camille Berchel, Laure Alexandre, Guy Merault, Monique Decastel

Publikováno v: Human Pathology. 30:13-20

Pathological changes often occur in the placenta of women with sickle cell disease (SCD). These alterations are caused by sickling of erythrocytes and vasoocclusion in the placental circulation, leading to regional hypoxia. However, the morphological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e85029d17c01d9e85c74e89347aa188
https://doi.org/10.1016/s0046-8177(99)90294-0

Effect of interleukin-8 and RANTES on the Gardos channel activity in sickle human red blood cells: role of the Duffy antigen receptor for chemokines

Autor: Marie-Dominique Hardy-Dessources, Pierre Couespel du Mesnil, Monique Decastel, Danitza Nebor, Jacques Elion, Marie-Claude Durpès, Danièle Mougenel

Publikováno v: Blood cells, moleculesdiseases. 44(4)

We investigated the effects of the chemokines IL-8 and RANTES on the activity of the Gardos channel (GC) of sickle red blood cells (SSRBCs). SSRBCs expressing the Duffy antigen receptor for chemokines (DARC) incubated under oxygenated conditions exhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43df25fa81d361fb980a5bf3d1ee463e
https://pubmed.ncbi.nlm.nih.gov/20199879

Organization of the endoplasmic reticulum-Golgi system is related to the state of enterocytic differentiation of human HT-29 cells

Autor: Michèle Aubery, Monique Decastel, Bénédicte Chazaud, Marie-Paule Muriel

Publikováno v: Differentiation; research in biological diversity. 60(3)

The organization of the endoplasmic reticulum (ER)-intermediate compartment (IC)-Golgi system was studied in tumoral HT-29 cells. Depending on the culture conditions, these cells are either undifferentiated or exhibit enterocytic differentiation afte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ca8c20cead9e01904c83884dcdfffd
https://pubmed.ncbi.nlm.nih.gov/8766597