HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells.

Autor: Tessa D Nauta, Monique C A Duyndam, Ester M Weijers, Victor M W van Hinsbergh, Pieter Koolwijk

Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0160700 (2016)

During short-term hypoxia, Hypoxia Inducible Factors (particular their subunits HIF-1α and HIF-2α) regulate the expression of many genes including the potent angiogenesis stimulator VEGF. However, in some pathological conditions chronic hypoxia occ

Externí odkaz: https://doaj.org/article/64a9546ae5e0470da414d4893da81869

HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells

Autor: Monique C. A. Duyndam, Ester M. Weijers, Victor W.M. van Hinsbergh, Pieter Koolwijk, Tessa D. Nauta

Publikováno v: Nauta, T D, Duyndam, M C A, Weijers, E M, van Hinsbergh, V W M & Koolwijk, P 2016, ' Correction : HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells ', PLoS ONE, vol. 11, no. 9, e0163840 . https://doi.org/10.1371/journal.pone.0163840
PLoS ONE, 11(9):e0163840. Public Library of Science
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0163840 (2016)

During short-term hypoxia, Hypoxia Inducible Factors (particular their subunits HIF-1α and HIF-2α) regulate the expression of many genes including the potent angiogenesis stimulator VEGF. However, in some pathological conditions chronic hypoxia occ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368ab4cc3cdd8b33a5955fc2033de66c
https://research.vumc.nl/en/publications/a6d45d74-752d-4d3a-900c-a83b934d123c

CD13/Aminopeptidase N overexpression by basic fibroblast growth factor mediates enhanced invasiveness of 1F6 human melanoma cells

Autor: M P A van Berkel, Linda H. Shapiro, Monique C. A. Duyndam, Epie Boven, Herbert M. Pinedo, Dennis Fontijn, Henk J. Broxterman, Yuana Yuana

Publikováno v: British Journal of Cancer

CD13/Aminopeptidase N (CD13) is known to play an important role in tumour cell invasion. We examined whether basic fibroblast growth factor (bFGF) is involved in the regulation of CD13 expression in human melanoma cells. 1F6 human melanoma cells were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e66ac4f35865a06c629dce502cbf5dc

Basic fibroblast growth factor (bFGF) in melanoma cells can upregulate vascular endothelial growth factor (VEGF) and CD13/aminopeptidase N, which is associated with accelerated growth, invasion and vascularization

Autor: Henk J. Broxterman, Epie Boven, M. Gallegoz Ruiz, Yuana Yuana, Herbert M. Pinedo, M P A van Berkel, Linda J.W. Bosch, Dennis Fontijn, Monique C. A. Duyndam, Linda H. Shapiro

Publikováno v: Melanoma Research. 16:S51

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44ec6e752cc2841e6a3cbb1a2ca18f83
https://doi.org/10.1097/00008390-200609001-00091